› › Structure analysis

Ubiquitin variant i53 mutant L67R bound to 53BP1 Tudor Domain

X-ray diffraction
1.16Å resolution
PDB entry 8svh coloured by chain, front view.
PDB entry 8svh coloured by chain, side view.
PDB entry 8svh coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Ubiquitin-like domain-containing protein and TP53-binding protein 1
hide full assembly name
Multimeric state: hetero dimer
Accessible surface area: 10299.12 Å2
Buried surface area: 1387.47 Å2
Dissociation area: 693.73 Å2
Dissociation energy (ΔGdiss): -0.06 kcal/mol
Dissociation entropy (TΔSdiss): 10.52 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-269994

Macromolecules

TP53-binding protein 1
Chain: A
Length: 124 amino acids
Theoretical weight: 13.92 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q12888 (Residues: 1484-1603; Coverage: 6%)
Gene name: TP53BP1
Pfam: Tumour suppressor p53-binding protein-1 Tudor
BRCT domain-containing protein in PDB entry 8svh, assembly 1, front view.
BRCT domain-containing protein in PDB entry 8svh, assembly 1, side view.
BRCT domain-containing protein in PDB entry 8svh, assembly 1, top view.
PDBe-KB: UniProt Coverage View: Q12888  
1124102030405060708090100110120
 
50100GPGSNSFVGLRVVAKWSSNGYFYSGKITRDVGAGKYKLLFDDGYECDVLGKDILLCDPIPLDTEVTALSEDEYFSAGVVKGHRKESGELYYSIEKEGQRKWYKRMAVILSLEQGNRLREQYGLG
UniProt
Q12888
Chains
Secondary structure
Interaction interfaces
Sequence conservation
Molecule details ›

Search similar proteins

Ubiquitin-like domain-containing protein
Chain: B
Length: 78 amino acids
Theoretical weight: 8.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: B4DV12 (Residues: 75-150; Coverage: 50%)
Gene name: UBB
Pfam: Ubiquitin family
Ubiquitin variant i53: mutant L67R in PDB entry 8svh, assembly 1, front view.
Ubiquitin variant i53: mutant L67R in PDB entry 8svh, assembly 1, side view.
Ubiquitin variant i53: mutant L67R in PDB entry 8svh, assembly 1, top view.
PDBe-KB: UniProt Coverage View: B4DV12  
17810203040506070
 
204060GPGSMLIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLAFAGKSLEDGRTLSDYNILKDSKRHPLLRLR
UniProt
B4DV12
Chains
Secondary structure
Interaction interfaces
Sequence conservation
Molecule details ›

Search similar proteins

Quick links