› 8sym

Electron Microscopy
3.2Å resolution

Human VPS29/VPS35L Complex (Locally refined map)

Released:
DOI: 10.2210/pdb8sym/pdb
PDB entry 8sym coloured by chain, front view.
PDB entry 8sym coloured by chain, side view.
PDB entry 8sym coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Structural organization of the retriever-CCC endosomal recycling complex.
Boesch DJ, Singla A, Han Y, Kramer DA, Liu Q, Suzuki K, Juneja P, Zhao X, Long X, Medlyn MJ, Billadeau DD, Chen Z, Chen B, Burstein E
Nat Struct Mol Biol (2023)
PMID: 38062209
Related structures: EMD-40884

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-234831 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
VPS35 endosomal protein-sorting factor-like Chain: A
Molecule details ›
Chain: A
Length: 963 amino acids
Theoretical weight: 109.7 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q7Z3J2 (Residues: 1-963; Coverage: 100%)
Gene names: 101F10.2, C16orf62, VPS35L
Vacuolar protein sorting-associated protein 29 Chain: B
Molecule details ›
Chain: B
Length: 205 amino acids
Theoretical weight: 23.04 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9UBQ0 (Residues: 2-182; Coverage: 100%)
  • Best match: Q9UBQ0-2 (Residues: 1-186)
Gene names: DC15, DC7, MDS007, VPS29
Sequence domains: Calcineurin-like phosphoesterase superfamily domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.2Å
Relevant EMDB volumes: EMD-40884
Expression system: Spodoptera frugiperda

Quick links

Citations

2 citation in other articles

Monocytic Differentiation of Human Acute Myeloid Leukemia Cells: A Proteomic and Phosphoproteomic Comparison of FAB-M4/M5 Patients with and without Nucleophosmin 1 Mutations.
Selheim et al. (2024)
1 more

2 mentions without citation

Structural Organization of the Retriever-CCC Endosomal Recycling Complex.
Boesch et al. (2023)
1 more