Function and Biology

Transporter associated with antigen processing (TAP) bound to the 9-mer peptide QYDDAVYKL

Source organisms:
Biochemical function: peptide transmembrane transporter activity
Biological process: transmembrane transport
Cellular component: TAP complex

EC 7.4.2.14: ABC-type antigen peptide transporter

Reaction catalysed:
ATP + H(2)O + antigen peptide(Side 1) = ADP + phosphate + antigen peptide(Side 2)
Systematic name:
ATP phosphohydrolase (ABC-type, antigen peptide-exporting)

Sequence families

Pfam Protein families (Pfam)
PF00005
Domain description: ABC transporter
Occurring in:
  1. Antigen peptide transporter 1
  2. Antigen peptide transporter 2
The deposited structure of PDB entry 8t4g contains 1 copy of Pfam domain PF00005 (ABC transporter) in Antigen peptide transporter 1. Showing 1 copy in chain A.
The deposited structure of PDB entry 8t4g contains 1 copy of Pfam domain PF00005 (ABC transporter) in Antigen peptide transporter 2. Showing 1 copy in chain B.

PF00664
Domain description: ABC transporter transmembrane region
Occurring in:
  1. Antigen peptide transporter 1
  2. Antigen peptide transporter 2
The deposited structure of PDB entry 8t4g contains 1 copy of Pfam domain PF00664 (ABC transporter transmembrane region) in Antigen peptide transporter 1. Showing 1 copy in chain A.
The deposited structure of PDB entry 8t4g contains 1 copy of Pfam domain PF00664 (ABC transporter transmembrane region) in Antigen peptide transporter 2. Showing 1 copy in chain B.