Function and Biology

Cryo-EM structure of MPL bound to TPO

Source organism: Mus musculus
Biochemical function: cytokine receptor activity
Biological process: cell population proliferation
Cellular component: membrane

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF09067
Domain description: Erythropoietin receptor, ligand binding
Occurring in:
  1. Thrombopoietin receptor
The deposited structure of PDB entry 8vu5 contains 2 copies of Pfam domain PF09067 (Erythropoietin receptor, ligand binding) in Thrombopoietin receptor. Showing 1 copy in chain C.

PF00758
Domain description: Erythropoietin/thrombopoietin
Occurring in:
  1. Thrombopoietin
The deposited structure of PDB entry 8vu5 contains 1 copy of Pfam domain PF00758 (Erythropoietin/thrombopoietin) in Thrombopoietin. Showing 1 copy in chain A.