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Human EBP complexed with compound 1

Electron Microscopy
2.8Å resolution
PDB entry 8w0r coloured by chain, front view.
PDB entry 8w0r coloured by chain, side view.
PDB entry 8w0r coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
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Multimeric state: homo dimer
Accessible surface area: 19509.02 Å2
Buried surface area: 3487.54 Å2
Dissociation area: 1,743.77 Å2
Dissociation energy (ΔGdiss): 22.01 kcal/mol
Dissociation entropy (TΔSdiss): 13.18 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-172224

Macromolecules

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
Chains: A, B
Length: 238 amino acids
Theoretical weight: 27.42 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q15125 (Residues: 2-230; Coverage: 100%)
Gene name: EBP
Pfam: EXPERA (EXPanded EBP superfamily)
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase in PDB entry 8w0r, assembly 1, front view.
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase in PDB entry 8w0r, assembly 1, side view.
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase in PDB entry 8w0r, assembly 1, top view.
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