› 8wye

Electron Microscopy
2.49Å resolution

Cryo-EM structure of DSR2-DSAD1 (partial) complex

Released:
DOI: 10.2210/pdb8wye/pdb
PDB entry 8wye coloured by chain, front view.
PDB entry 8wye coloured by chain, side view.
PDB entry 8wye coloured by chain, top view.
Source organisms:
Primary publication:
Structural basis for phage-mediated activation and repression of bacterial DSR2 anti-phage defense system.
Zhang JT, Liu XY, Li Z, Wei XY, Song XY, Cui N, Zhong J, Li H, Jia N
OpenAccess logo Nat Commun 15 2797 (2024)
PMID: 38555355
Related structures: EMD-37925

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-246243 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SIR2-like domain-containing protein Chains: A, B, D, E
Molecule details ›
Chains: A, B, D, E
Length: 1005 amino acids
Theoretical weight: 118.64 KDa
Source organism: Bacillus subtilis
Expression system: Escherichia coli
UniProt:
  • Canonical: D4G637 (Residues: 1-1005; Coverage: 100%)
Gene name: BSNT_07056
Sequence domains: SIR2-like domain
Bacillus phage SPbeta DSAD1 protein Chain: C
Molecule details ›
Chain: C
Length: 146 amino acids
Theoretical weight: 16.59 KDa
Source organism: Bacillus phage SPBc2
Expression system: Escherichia coli
UniProt:
  • Canonical: O64191 (Residues: 1-120; Coverage: 100%)
Gene name: yotI

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 2.49Å
Relevant EMDB volumes: EMD-37925
Expression system: Escherichia coli

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