› › Structure analysis

Crystal structure of human secretory glutaminyl cyclase in complex with (S)-1-(1H-benzo[d]imidazol-5-yl)-5-(4-propoxyphenyl)imidazolidin-2-one

X-ray diffraction
3.24Å resolution
PDB entry 8xgb coloured by chain, front view.
PDB entry 8xgb coloured by chain, side view.
PDB entry 8xgb coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Glutaminyl-peptide cyclotransferase
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 13974.75 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-172570

Macromolecules

Glutaminyl-peptide cyclotransferase
Chain: B
Length: 331 amino acids
Theoretical weight: 37.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16769 (Residues: 32-361; Coverage: 99%)
Gene name: QPCT
Pfam: Peptidase family M28
Glutaminyl-peptide cyclotransferase in PDB entry 8xgb, assembly 1, front view.
Glutaminyl-peptide cyclotransferase in PDB entry 8xgb, assembly 1, side view.
Glutaminyl-peptide cyclotransferase in PDB entry 8xgb, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links