Function and Biology Details
Reaction catalysed:
Angiotensin II + H(2)O = angiotensin-(1-7) + L-phenylalanine
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144662 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (5 distinct):
Spike glycoprotein
Molecule details ›
Chains: A, B, C
Length: 1245 amino acids
Theoretical weight: 138.06 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
Sequence domains:
Length: 1245 amino acids
Theoretical weight: 138.06 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
- Canonical:
P0DTC2 (Residues: 12-1210; Coverage: 95%)
Sequence domains:
Processed angiotensin-converting enzyme 2
Molecule details ›
Chain: D
Length: 608 amino acids
Theoretical weight: 70.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Sequence domains: Angiotensin-converting enzyme
Length: 608 amino acids
Theoretical weight: 70.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q9BYF1 (Residues: 19-617; Coverage: 76%)
Sequence domains: Angiotensin-converting enzyme
Ligands and Environments
1 bound ligand:
No modified residues
