Assemblies
Assembly Name:
SARS-CoV-2 uncleaved Spike protein complex and Processed angiotensin-converting enzyme 2
Multimeric state:
hetero tetramer
Accessible surface area:
170332.58 Å2
Buried surface area:
39962.72 Å2
Dissociation area:
809.07
Å2
Dissociation energy (ΔGdiss):
-10.26
kcal/mol
Dissociation entropy (TΔSdiss):
15.8
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-144662
Macromolecules
Chains: A, B, C
Length: 1245 amino acids
Theoretical weight: 138.06 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
Pfam:
Length: 1245 amino acids
Theoretical weight: 138.06 KDa
Source organism: Severe acute respiratory syndrome coronavirus 2
Expression system: Homo sapiens
UniProt:
- Canonical:
P0DTC2 (Residues: 12-1210; Coverage: 95%)
Pfam:
Chain: D
Length: 608 amino acids
Theoretical weight: 70.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Pfam: Angiotensin-converting enzyme
Length: 608 amino acids
Theoretical weight: 70.49 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical:
Q9BYF1 (Residues: 19-617; Coverage: 76%)
Pfam: Angiotensin-converting enzyme