Function and Biology Details
Reaction catalysed:
Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-Casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec; and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetradecamer (preferred)
Assembly name:
ATP-dependent Clp protease proteolytic subunit (preferred)
PDBe Complex ID:
PDB-CPX-242121 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
ATP-dependent Clp protease proteolytic subunit
Molecule details ›
Chains: A, B, C, D, E, F, G
Length: 210 amino acids
Theoretical weight: 22.63 KDa
Source organism: Streptomyces hawaiiensis
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Clp protease
Length: 210 amino acids
Theoretical weight: 22.63 KDa
Source organism: Streptomyces hawaiiensis
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
A0A5B9BGY8 (Residues: 31-219; Coverage: 86%)
Sequence domains: Clp protease
ATP-dependent Clp protease proteolytic subunit
Molecule details ›
Chains: H, I, J, K, L, M, N
Length: 220 amino acids
Theoretical weight: 24.04 KDa
Source organism: Streptomyces hawaiiensis
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Clp protease
Length: 220 amino acids
Theoretical weight: 24.04 KDa
Source organism: Streptomyces hawaiiensis
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: A0A5B9BIX9 (Residues: 52-235; Coverage: 78%)
Sequence domains: Clp protease
