› 8xoa

Electron Microscopy
3.03Å resolution

VMAT2 complex with MPP+

Released:
DOI: 10.2210/pdb8xoa/pdb
PDB entry 8xoa coloured by chain, front view.
PDB entry 8xoa coloured by chain, side view.
PDB entry 8xoa coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Jiang DH, Wu D
Related structures: EMD-38524

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-233030 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Synaptic vesicular amine transporter Chain: A
Molecule details ›
Chain: A
Length: 573 amino acids
Theoretical weight: 61.93 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05940 (Residues: 18-474; Coverage: 89%)
Gene names: SLC18A2, SVMT, VMAT2
Sequence domains: Major Facilitator Superfamily

Ligands and Environments

1 bound ligand:
Ligand WRF 1 x WRF
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.03Å
Relevant EMDB volumes: EMD-38524
Expression system: Homo sapiens

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