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VMAT2 complex with MPP+

Electron Microscopy
3.03Å resolution
PDB entry 8xoa coloured by chain, front view.
PDB entry 8xoa coloured by chain, side view.
PDB entry 8xoa coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Synaptic vesicular amine transporter
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Multimeric state: monomeric
Accessible surface area: 15752.02 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-233030

Macromolecules

Synaptic vesicular amine transporter
Chain: A
Length: 573 amino acids
Theoretical weight: 61.93 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05940 (Residues: 18-474; Coverage: 89%)
Gene names: SLC18A2, SVMT, VMAT2
Pfam: Major Facilitator Superfamily
Synaptic vesicular amine transporter in PDB entry 8xoa, assembly 1, front view.
Synaptic vesicular amine transporter in PDB entry 8xoa, assembly 1, side view.
Synaptic vesicular amine transporter in PDB entry 8xoa, assembly 1, top view.
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