9bdp

Electron Microscopy
3.7Å resolution

80S ribosome bound with angiogenin and complex of eEF1A and Ala-tRNAAla

Released:

Function and Biology Details

Reaction catalysed:
The C-O-P bond 3' to the apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero 86-mer (preferred)
PDBe Complex ID:
PDB-CPX-268547 (preferred)
Entry contents:
78 distinct polypeptide molecules
7 distinct RNA molecules
Macromolecules (85 distinct):
Large ribosomal subunit protein uL2 Chain: AL02
Molecule details ›
Chain: AL02
Length: 248 amino acids
Theoretical weight: 27 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TT27 (Residues: 2-249; Coverage: 97%)
Gene name: RPL8
Sequence domains:
Large ribosomal subunit protein uL3 Chain: AL03
Molecule details ›
Chain: AL03
Length: 394 amino acids
Theoretical weight: 45.12 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: G1TL06 (Residues: 2-395; Coverage: 98%)
Gene name: RPL3
Sequence domains: Ribosomal protein L3
Large ribosomal subunit protein uL4 Chain: AL04
Large ribosomal subunit protein uL18 Chain: AL05
Large ribosomal subunit protein eL6 Chain: AL06
Large ribosomal subunit protein uL30 Chain: AL07
Large ribosomal subunit protein eL8 Chain: AL08
Large ribosomal subunit protein uL6 Chain: AL09
Large ribosomal subunit protein uL16 Chain: AL10
Large ribosomal subunit protein uL5 Chain: AL11
Large ribosomal subunit protein uL11 Chain: AL12
Large ribosomal subunit protein eL13 Chain: AL13
Large ribosomal subunit protein eL14 Chain: AL14
Large ribosomal subunit protein eL15 Chain: AL15
Large ribosomal subunit protein uL13 Chain: AL16
Large ribosomal subunit protein uL22 Chain: AL17
Large ribosomal subunit protein eL18 Chain: AL18
Large ribosomal subunit protein eL19 Chain: AL19
Large ribosomal subunit protein eL20 Chain: AL20
Large ribosomal subunit protein eL21 Chain: AL21
Large ribosomal subunit protein eL22 Chain: AL22
Large ribosomal subunit protein uL14 Chain: AL23
Large ribosomal subunit protein eL24 Chain: AL24
Large ribosomal subunit protein uL23 Chain: AL25
Large ribosomal subunit protein uL24 Chain: AL26
Large ribosomal subunit protein eL27 Chain: AL27
Large ribosomal subunit protein uL15 Chain: AL28
Large ribosomal subunit protein eL29 Chain: AL29
Large ribosomal subunit protein eL30 Chain: AL30
Large ribosomal subunit protein eL31 Chain: AL31
Large ribosomal subunit protein eL32 Chain: AL32
Large ribosomal subunit protein eL33 Chain: AL33
Large ribosomal subunit protein eL34 Chain: AL34
Large ribosomal subunit protein uL29 Chain: AL35
Large ribosomal subunit protein eL36 Chain: AL36
Large ribosomal subunit protein eL37 Chain: AL37
Large ribosomal subunit protein eL38 Chain: AL38
Large ribosomal subunit protein eL39 Chain: AL39
Large ribosomal subunit protein eL40 Chain: AL40
Small ribosomal subunit protein eS32 Chain: AL41
Ribosomal protein L36a Chain: AL42
Large ribosomal subunit protein eL43 Chain: AL43
Large ribosomal subunit protein eL28 Chain: ALNW
Large ribosomal subunit protein uL10 Chain: ALP0
Angiogenin Chain: ANG
Small ribosomal subunit protein RACK1 Chain: ARAC
40S ribosomal protein SA Chain: AS00
Small ribosomal subunit protein eS1 Chain: AS01
Small ribosomal subunit protein uS5 Chain: AS02
Small ribosomal subunit protein uS3 Chain: AS03
40S ribosomal protein S4 Chain: AS04
Small ribosomal subunit protein uS7 Chain: AS05
Small ribosomal subunit protein eS6 Chain: AS06
Small ribosomal subunit protein eS7 Chain: AS07
Small ribosomal subunit protein eS8 Chain: AS08
Small ribosomal subunit protein uS4 Chain: AS09
Small ribosomal subunit protein eS10 Chain: AS10
Small ribosomal subunit protein uS17 Chain: AS11
Small ribosomal subunit protein eS12 Chain: AS12
Small ribosomal subunit protein uS15 Chain: AS13
Small ribosomal subunit protein uS11 Chain: AS14
Small ribosomal subunit protein uS19 Chain: AS15
Small ribosomal subunit protein uS9 Chain: AS16
Small ribosomal subunit protein eS17 Chain: AS17
Small ribosomal subunit protein uS13 Chain: AS18
Small ribosomal subunit protein eS19 Chain: AS19
Small ribosomal subunit protein uS10 Chain: AS20
Small ribosomal subunit protein eS21 Chain: AS21
Small ribosomal subunit protein uS8 Chain: AS22
Small ribosomal subunit protein uS12 Chain: AS23
40S ribosomal protein S24 Chain: AS24
40S ribosomal protein S25 Chain: AS25
Small ribosomal subunit protein eS26 Chain: AS26
Small ribosomal subunit protein eS27 Chain: AS27
Small ribosomal subunit protein eS28 Chain: AS28
Small ribosomal subunit protein uS14 Chain: AS29
Small ribosomal subunit protein eS30 Chain: AS30
Elongation factor 1-alpha Chain: EF1A
18S Ribosomal RNA Chain: A18S
28S ribosomal RNA Chain: A28S
5.8S ribosomal RNA Chain: A58S
5S ribosomal RNA Chain: A5S
tRNAfMet Chains: ETRN, PTRN
Messenger RNA Chain: MRNA
tRNAAla Chain: TIRN

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.7Å
Relevant EMDB volumes: EMD-44464
Expression system: Escherichia coli