9brr

Electron Microscopy
4.5Å resolution

Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O + 4 H(+)(Side 1) = ADP + phosphate + 4 H(+)(Side 2)

Structure analysis Details

Assembly composition:
hetero 32-mer (preferred)
PDBe Complex ID:
PDB-CPX-273834 (preferred)
Entry contents:
16 distinct polypeptide molecules
Macromolecules (16 distinct):
V-type proton ATPase 21 kDa proteolipid subunit c'' Chain: b
Molecule details ›
Chain: b
Length: 205 amino acids
Theoretical weight: 21.62 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q91V37 (Residues: 1-205; Coverage: 100%)
Gene names: Atp6f, Atp6v0b
Sequence domains: ATP synthase subunit C
V-type proton ATPase 16 kDa proteolipid subunit c Chains: g, h, i, j, k, l, m, n, o
Molecule details ›
Chains: g, h, i, j, k, l, m, n, o
Length: 155 amino acids
Theoretical weight: 15.82 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P63082 (Residues: 1-155; Coverage: 100%)
Gene names: Atp6c, Atp6l, Atp6v0c, Atpl, Mvp
Sequence domains: ATP synthase subunit C
V-type proton ATPase catalytic subunit A Chains: 0, 1, 2
V-type proton ATPase subunit B, brain isoform Chains: 3, 4, 5
V-type proton ATPase subunit D Chain: 7
V-type proton ATPase subunit E 1 Chains: 8, 9, Q
V-type proton ATPase subunit G 2 Chains: R, T, V
V-type proton ATPase subunit F Chain: X
V-type proton ATPase subunit C 1 Chain: 6
V-type proton ATPase subunit H Chain: U
V-type proton ATPase subunit d 1 Chain: d
V-type proton ATPase 116 kDa subunit a 1 Chain: a
V-type proton ATPase subunit e 2 Chain: e
Ribonuclease kappa Chain: f
V-type proton ATPase subunit S1 Chain: c
Renin receptor Chain: p

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 4.5Å
Relevant EMDB volumes: EMD-44841