› 9cf0

Electron Microscopy
3.47Å resolution

Parasitella parasitica Fanzor (PpFz) State 1

Released:
DOI: 10.2210/pdb9cf0/pdb
PDB entry 9cf0 coloured by chain, front view.
PDB entry 9cf0 coloured by chain, side view.
PDB entry 9cf0 coloured by chain, top view.
Source organisms:
Primary publication:
Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Xu P, Saito M, Faure G, Maguire S, Chau-Duy-Tam Vo S, Wilkinson ME, Kuang H, Wang B, Rice WJ, Macrae RK, Zhang F
Cell (2024)
PMID: 39208796
Related structures: EMD-45525

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero pentamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-493102 (preferred)
Entry contents:
2 distinct polypeptide molecules
2 distinct DNA molecules
1 distinct RNA molecule
Macromolecules (5 distinct):
Peptidyl-prolyl cis-trans isomerase Chain: C
Molecule details ›
Chain: C
Length: 162 amino acids
Theoretical weight: 17.41 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P14832 (Residues: 1-162; Coverage: 100%)
Gene names: CPH1, CPR1, CYP1, SCC1, YD8358.10C, YDR155C
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Maltose/maltodextrin-binding periplasmic protein Chain: P
Molecule details ›
Chain: P
Length: 1259 amino acids
Theoretical weight: 144.41 KDa
Source organisms: Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P0AEX9 (Residues: 27-392; Coverage: 99%)
  • Canonical: A0A0B7NJM7 (Residues: 2-849; Coverage: 100%)
Gene names: JW3994, PARPA_09356.1 scaffold 36248, b4034, malE
Sequence domains: Bacterial extracellular solute-binding protein
DNA non-target strand Chain: N
Molecule details ›
Chain: N
Length: 57 nucleotides
Theoretical weight: 17.45 KDa
DNA target strand Chain: T
Molecule details ›
Chain: T
Length: 57 nucleotides
Theoretical weight: 17.68 KDa
Parasitella parasitica Fanzor 1 omegaRNA Chain: W
Molecule details ›
Chain: W
Length: 61 nucleotides
Theoretical weight: 19.51 KDa

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Resolution: 3.47Å
Relevant EMDB volumes: EMD-45525
Expression system: Saccharomyces cerevisiae

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