Structure analysis

Structure of human MAIT A-F7 TCR in complex with human MR1-Pyridoxal-5'-phosphate

X-ray diffraction
2Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 4 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
PDBe Complex ID: PDB-CPX-281649
Assembly 2
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Multimeric state: hetero tetramer
PDBe Complex ID: PDB-CPX-281649

Macromolecules

Chains: A, C
Length: 271 amino acids
Theoretical weight: 31.94 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q95460 (Residues: 23-292; Coverage: 85%)
Gene name: MR1
Pfam:

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Chains: B, F
Length: 100 amino acids
Theoretical weight: 11.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Pfam: Immunoglobulin C1-set domain

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Chains: D, G
Length: 204 amino acids
Theoretical weight: 22.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q6P4G7 (Residues: 6-213; Coverage: 78%)
Gene name: TRA@
Pfam:

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Chains: E, H
Length: 246 amino acids
Theoretical weight: 27.68 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli

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