Featured Structure Articles
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Structure of a left-handed DNA G-quadruplex.
PDB entry: 4u5m The iconic double helical structure of B-form DNA needs no introduction, but DNA can take on several different structures too. G-quadruplex DNA is formed from guanine-rich DNA sequences which are found in the telomeres. |
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Structure of an allergen from surgical gloves
PDB 4wp4: |
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Cryo-EM structure of the Dark apoptosome.
EMDB EMD-2871: The apoptosome, which comprises 16 molecules of the Dark protein, facilitates autocatalytic activation of caspase, which starts the process of apoptosis, or cell death. |
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FGFR1 with an inhibitor
PDB 4ux0: Fibroblast growth factor receptors (FGFRs) are recognized therapeutic targets in cancer. Structures released on 25th February describe insights underpinning the impact of mutations on these proteins on drug efficacy. |
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Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Ramp2 Response Element.
PDB 4cn2: |