Troponin T, cardiac muscle

Gene:

TNNT2 Disease Cardiomyopathy, familial hypertrophic, 2: A hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain... [click for more]

Organism:

Homo sapiens (Human)

Uniprot:

P45379go to UniProt

Biological function:

Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activitygo to UniProt

Representative structure for UniProt P45379

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PDB 7utl chain EA (observed residues)
PDB 7utl chain EA (observed residues)

PDB chain shown: 7utl EA go to PDBe

UniProt residues 1 - 298

Coverage: 21%

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15
Structures

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4
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5
Similarity

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166
Publications

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