Proteasome-associated ATPase

Gene:

mpa

Organism:

Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)

Uniprot:

P9WQN5go to UniProt

Biological function:

ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key ... [show more]go to UniProt

Representative structure for UniProt P9WQN5

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PDB 8d6y chain A (observed residues)
PDB 8d6y chain A (observed residues)
PDB 8d6y chain A (observed residues)
PDB 8d6y chain A (observed residues)
PDB 8d6y chain A (observed residues)
PDB 8d6y chain A (observed residues)

PDB chain shown: 8d6y A go to PDBe

UniProt residues 1 - 609

Coverage: 79%

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16
Structures

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3
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3
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222
Similarity

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71
Publications

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