Zinc finger and BTB domain-containing protein 17

Gene:

ZBTB17

Organism:

Homo sapiens (Human)

Synonyms:

MIZ1, ZNF151, ZNF60

Uniprot:

Q13105go to UniProt

Biological function:

Transcription factor that can function as an activator or repressor depending on its binding partners, and by targeting negative regulators of cell cycle progression. Plays a critical role in early lymphocyte development, where it is essential to prevent apoptosis in lymphoid precursors, allowing them to survive in response to IL7 and undergo proper lineage commitment. Has been shown to bind ... [show more]go to UniProt

Representative structures for UniProt Q13105

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PDB 7azw chain B (observed residues)
PDB 7azw chain B (observed residues)
PDB 2n26 chain A (observed residues)
PDB 2n26 chain A (observed residues)
PDB 2m0f chain A (observed residues)
PDB 2m0f chain A (observed residues)
PDB 7mc2 chain A (observed residues)
PDB 7mc2 chain A (observed residues)
PDB 5ion chain A (observed residues)
PDB 5ion chain A (observed residues)

PDB chain shown: 7azw B go to PDBe

UniProt residues 1 - 115

Coverage: 15%

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19
Structures

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5
Ligands

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2
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6
Similarity

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27
Publications

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