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Angiotensin-converting enzyme 2
Mus musculus (Mouse)
Q8R0I0go to UniProt
Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin I to angiotensin 1-9, a nine-amino acid peptide with anti-hypertrophic effects in cardiomyocytes, and angiotensin II to angiotensin 1-7, which then acts as a beneficial vasodilator and anti-proliferation agent, counterbalancing the actions of the vasoconstrictor ... [show more]go to UniProt
Representative structure for UniProt Q8R0I0
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PDB chain shown: 8dma B go to PDBe
UniProt residues 1 - 615
Coverage: 74%