Target of rapamycin complex subunit LST8

Gene:

MLST8

Organism:

Homo sapiens (Human)

Synonyms:

GBL, LST8

Uniprot:

Q9BVC4go to UniProt

Biological function:

Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals (PubMed:12718876, PubMed:15268862, PubMed:15467718, PubMed:24403073, PubMed:28489822). mTORC1 is activated in response to growth factors or amino acids (PubMed:12718876, PubMed:15268862, [show more]go to UniProt

Representative structure for UniProt Q9BVC4

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PDB 8era chain C (observed residues)
PDB 8era chain C (observed residues)
PDB 8era chain C (observed residues)
PDB 8era chain C (observed residues)

PDB chain shown: 8era C go to PDBe

UniProt residues 1 - 326

Coverage: 94%

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32
Structures

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17
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3
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246
Similarity

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359
Publications

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