part of PF06971

homologous to the MarR-like family in the DNA-binding region but dimerizes differently through the N- and C-terminal helical extensions to the common fold; Pfam assigns its WHD in the ArsR family (PF01022)

PF01399

overlaps with PF01022; the N- and C-terminal helical extensions to the common fold form the dimer interface

no Pfam; contains long helix in the C-terminal extension, forms dimer similar to the RTP and LysR dimers

PF00392

PF14947; contains long helix in the C-terminal extension, forms dimer similar to the RTP and LysR dimers

PF01978; The N- and C-terminal helical extensions to the common fold form the dimer interface, distinct from other known families

PF01628 for the C-terminal domain; similar domain organization to the transcriptional regulator IclR

PF09114; the N- and C-terminal helical extensions to the common fold form the dimer interface (distinct from that of ArsR-like family)

duplication: tandem repeat of two winged helix domains arranged with the pseudo twofold symmetry

PF10075

duplication: tandem repeat of two winged-helix domains

follows the extended AAA-ATPase domain

NULL

PF02082

CD: PF14544 (DUF4443)

PF04703

PF12976 ((DUF3860)

homologous to the MarR-like family in the DNA-binding region but has a different dimerisation subdomain

PF07515 (DUF1528), the wing hairpin, linker between helices 1 and 2 and the C-terminal tail together form an open beta-sheet barrel

no Pfam; probable biological unit is a homohexamer

PF04337, DUF480, duplication: two winged helix domains are tightly packed back-to-back about pseudo twofold axis

PF11625 (DUF3253)

contains extra N-terminal helix

PF09639

PF01475; contains extra N-terminal helix and an alpha+beta dimerisation subdomain

PF09645

follows the tandem AAA-ATPase domain

heterodimer of two homologous chains

similar domain architecture to AAA+ helicases

PF02295

C-terminus passes through the first loop

no Pfam; insertion of a zinc-ribbon subdomain in the beta-hairpin wing

ND: PF13338, CD: PF09407

PF01090, local sequence similarity to members of the GntR-like family

middle region of PF05158

PF05383, RNA-binding domain

PF03243

PF00605

circularly permuted version of the winged helix fold

fusion of 'winged helix' and methyltransferase domains

The N- and C-terminal helical extensions to the common fold form the dimer interface

helix-loop insertion in the HTH motif

PF04079 duplication: tandem repeat of two winged helix domains, forms a dimer via the C-terminal domain

PF04824

PF03551, related to the MarR-like family

ND partial hit to PF01022; contains the extra C-terminal histone-fold domain with non-canonical dimerisation mode

PF09012; FeoC-like transcriptional regulator

octamer: tetramer of dimers

no Pfam; found N-terminal to ROK domain in some proteins

PF01022 in the N-terminal part; sequence similarity to PH1932 in the N-terminal domain, the C-terminal domain provides new dimerisation interface made of a beta-hairpin and a coiled coil

PF03882

PF08222

PF01638, the N- and C-terminal helical extensions to the common fold form the dimer interface similar to that of the ArsR-like family

PF09397

peptide-binding motif

PF00293 partial hit to ND; contains the C-terminal winged helix domain

PF00610

PF00126; contains long helix in the C-terminal extension, forms dimer similar to the RTP dimer

PF09339

PF10557

duplication: tandem repeat of four winged helix domains

no Pfam; shows sequence similarity to the ArsR-like transcriptional regulators, but lacks its extra C-terminal helix and forms a different dimerisation interface

duplication: tandem repeat of two modified winged-helix domains

PF10357

Man1-Src1p-C-terminal domain: PF09402

N-terminal part of PF16095; comprises tandem repeat of 2 winged helix domains

N-terminal part of PF09507; variant WHD with an insetion of alpha-beta unit into the tip of the "wing"

PF16221 CL0123; circular permutation of the Winged Helix domain fold

PF03962 CL0123

PF09651, global similarity to SCOP ID 4007634

PF16365, forms strand-swapped homodimers

PF10771 (DUF2582) CL0123

PF04288

PF09904 (DUF2131) CL0123

PF16679

PF11564; duplication: tandem repeat of two winged-helix domains

PF05066 CL0123; HB1, ASXL, restriction endonuclease HTH domain

PF05402

PF05584 CL0123

PF05719, duplication, consists of two repeats, one of which is inserted into the other, the inserted repeat is circularly permuted

PF07106 CL0123

PF01454

PF14465

PF14705 , lacks DNA-binding activity

PF03297

PF03501

PF03574

derived from PF09734; includes a 3-helical subdomain C-terminal to WHD

N-terminal part of PF09491; consists of two variant WHDs and a 3-helical bundle linker domain

PF1689

PF18685 CL0123

PF09468