The Electron Microscopy Data Bank (EMDB) is a public repository for cryogenic-sample Electron Microscopy (cryoEM) volumes and representative tomograms of macromolecular complexes and subcellular structures. It covers a variety of techniques, including single-particle analysis, helical reconstruction, electron tomography, subtomogram averaging, and electron crystallography. More...
As of 27 November 2024, EMDB contains 40492 entries (latest entries, trends).
EMDB News
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06 January 2024: We are delighted to share that EMDB has officially been elevated to a Core Data Resource by ELIXIR, recognising it as a European data resource of fundamental importance to the wider life-science community and the long-term preservation of biological data.
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22 November 2023: We are happy to share the most recent version of the EMDB Nucleic Acids Research paper. The paper describes recent developments and future plans of the EMDB in the context of the worldwide Protein Data Bank. Check it out now! https://doi.org/10.1093/nar/gkad1019
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Cryo-EM strcuture of the magnesium channel CtMrs2 in the closed state
CSTET Tomogram of a Mitochondrion from MFF-/- MEFs under fission inducing conditions
The molecular architecture of the murine kidney slit diaphragm revealed by cryo-electron tomography
Cryo-EM structure of the magnesium channel CtMrs2 in the open state
Human Adenovirus 5 (Ad5) and Coagulation Factor X (FX) complex at 3.6A resolution.
Cryo-STEM tomogram of a Mitochondrion from MFF-/- MEFs under fission inducing conditions
Human divalent metal transporter 1 (DMT1/SLC11A2) in complex with sybody 1, in an occluded state
Cryo-electron tomogram of H. borinquense showing extended T6SS complex
Cryo-electron tomogram of H. elongans showing contracted T6SS complex
Human divalent metal transporter 1 (DMT1/SLC11A2) in complex with manganese, in an occluded state
Cryo-electron tomogram of H. borinquense showing contracted T6SS complex
Sub-tomogram average of extended baseplate complex in H. borinquense with C6 symmetry
Sub-tomogram average of contracted sheath complex in H. borinquense with C6 symmetry.
Cryo-electron tomogram of H. elongans showing extended T6SS complex
Dual-axis CSTET tomogram of mitochondria from MFF-/- U2-OS cells under fission-inducing conditions
Sub-tomogram average of extended baseplate complex in H. borinquense without imposing symmetry
The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4R313PRR mutant
Human Adenovirus 6 (Ad6) and Coagulation Factor II (Prothrombin) complex at 3.7A resolution
Structure of Clostridioides difficile Component A (50-463) in Complex with a CDTb Oligomer
Focused classification of dsDNA nucleic acid density from in vitro CHMP1B/IST1 copolymer filaments - Class5
Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ATPyS
Human adenovirus 6 (Ad6) in complex with coagulation Factor FX at 5.0A resolution.
Local refined map for Nap1 and H2A-H2B region in (Nap1)2-H2A-H2B-Kap114-RanGTP structure
Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ADP
Structure of type II-2 alpha-synuclein filament from multiple system atrophy
4.33 Angstrom Haemoglobin reconstruction from data collected on a standard 120-keV LaB6 electron microscope (Tecnai G2 spirit) fitted with Gatan Alpine camera (a 100keV optimised direct electron detector).
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Mu (B.1.621) variant 3 closed RBDs
Human Adenovirus 657 (Ad657) and Coagulation factor II (Prothrombin) at 4.17A resolution.
Reconstruction from 120,000 particles of apoferritin imaged with a round aperture
Reconstruction from 120,000 particles of apoferritin imaged with a square aperture
cryo-EM structure of a non-neutralizing antibody V3-21 in complex with SARS-CoV-2 spike
Cryo-EM model derived from localized reconstruction of Ad657-hexon-FII complex at 4.14A resolution
Structure of UT14 Fab in complex with the head domain of H3 (A/Singapore/INFIMH-16-0019/2016)
Human adenovirus 5 (Ad5) in complex with coagulation Factor II (Prothrombin) at 4.13 resolution.
Cryo-EM model derived from localized reconstruction of Ad657-hexon-FX complex at 3.86A resolution
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Delta (B.1.617.2) variant 3 closed RBDs
Focused classification of dsDNA nucleic acid density from in vitro CHMP1B/IST1 copolymer filaments - Class1
The structure of LSD1-CoREST-HDAC1 in complex with KBTBD4IPR310delinsTTYML
Focused classification of dsDNA nucleic acid density from in vitro CHMP1B/IST1 copolymer filaments - Class2
Cryo-EM model derived from localized reconstruction of human adenovirus (Ad5)-hexon-FX complex at 3.6A resolution
Cryo-EM model derived from localized reconstruction of human adenovirus 6 (Ad6)-hexon-FII complex
Human Adenovirus 657 (Ad657) and Coagulation Factor X (FX)complex at 4.0A resolution
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: B.1 variant 3 closed RBDs
Local refined map for Nap1 region from (Nap1)2-Kap114-H2A-H2B structure
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Gamma (P.1) variant 3 closed RBDs
2.65 Angstrom Apoferritin single particle cryo-EM reconstruction from a standard 120-keV LaB6 electron microscope (Tecnai G2 spirit) fitted with Gatan Alpine camera (a 100keV optimised direct electron detector).
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: B.1 variant 1 open RBD
Consensus olfactory receptor consOR2 bound to S-carvone and in complex with mini-Gs trimeric protein (transmembrane domain)
Structure of type I-2 alpha-synuclein filament from multiple system atrophy
Streptomyces griseus Family 2B encapsulin shell with 2-methylisoborneol synthase cargo
Locally refined map for Nap1 and H2A-H2B in (Nap1)2-H2A-H2B-Kap114 structure
Consensus olfactory receptor consOR51 in complex with mini-Gs trimeric protein (transmembrane domain)
Focused classification of dsDNA nucleic acid density from in vitro CHMP1B/IST1 copolymer filaments - Class9
Focused classification of dsDNA nucleic acid density from in vitro CHMP1B/IST1 copolymer filaments - Class4
Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ATP
cryo-EM structure of a non-neutralizing antibody V6-12 in complex with SARS-CoV-2 spike
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Alpha (B.1.1.7) variant 3 closed RBDs
Consensus olfactory receptor consOR1 bound to L-menthol and in complex with mini-Gs trimeric protein (transmembrane domain)
Cryo-EM model derived from localized reconstruction of human adenovirus 5 (Ad5)-hexon-FII complex at 3.9A resolution
4.4 Angstrom single particle cryo-EM reconstruction of Human M4 muscarinic acetylcholine receptor complex. Data collected on 120kV LaB6 electron microscope Tecnai G2 spirit fitted with Gatan Alpine camera.
Cryo-EM structure of SARS-CoV-2 Spike Proteins on intact virions: Alpha (B.1.1.7) variant 1 open RBD
The structure of HDAC2-CoREST in complex with KBTBD4R313PRR mutant
Cryo-EM model derived from localized reconstruction of human adenovirus 6-hexon-FX complex at 4.3A resolution
Cryo-EM structure of ferritin variant R63BrThA/E67BrThA with Cu(II)
Cryo-EM structure of mGlu2-mGlu4 heterodimer bound mGlu4 agonist E7P
consensus map of Human Lysophosphatidic Acid Receptor 1-Gi complex bound to CpY
PSII core monomer (adjacent to LHCI) of PSI-PSII from Chlamydomonas reinhardtii
Structure of influenza A virus RNA polymerase PB1 and nuclear import host factor RanBP5 complex
Cryo-EM structure of Semliki Forest virus in complex with its receptor VLDLR(2-fold)
Cryo-EM structure of the Mmp1 encapasulin from Mycobacterium smegmatis
Cryo-EM structure of mGlu2-mGlu4 heterodimer bound mGlu4 agonist E7P
S/M/N-LHCII (adjacent to LHCI) of PSI-PSII from Chlamydomonas reinhardtii
N-LHCII (adjacent to LHCI) of PSI-PSII from Chlamydomonas reinhardtii
Immunoglobulin (IgG) reconstruction using phase plate single-particle cryo-EM
S-LHCII & CP26 (adjacent to LHCI) of PSI-PSII from Chlamydomonas reinhardtii
Cryo-EM structure of Semliki Forest virus in complex with its receptor VLDLR(3-fold)
Focused map of Human Lysophosphatidic Acid Receptor 1-Gi complex bound to CpY
Structure of the multidrug efflux pump EfpA from M. tuberculosis complexed with lipids
Cryo-EM structure of Semliki Forest virus in complex with its receptor VLDLR(5-fold)
Fab domain of Immunoglobulin (IgG) reconstruction using conventional single-particle cryo-EM
Fab domain of Immunoglobulin (IgG) reconstruction using phase plate single-particle cryo-EM
Cryo-EM structure of the GLP-1(9-36)-bound human GLP-1R-Gs complex
Sub-tomogram average of extended sheath complex in H. borinquense with C6 symmetry