EMDB < Search results

EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

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author:"Peak-Chew SY" AND xref_links:"pdb" AND sample_type:"protein" AND author_name:"Lavenir I"

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EMD-16022

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Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42

Release date: Jan. 18, 2023
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 8bfz
Q-score: 0.621

Yang Y, Zhang W, Murzin AG, Schweighauser M, Huang M, Lovestam S, Peak-Chew SY, Saito T, Saido TC, Macdonald J, Lavenir I, Ghetti B, Graff C, Kumar A, Nordberg A, Goedert M, Scheres SHW

Acta Neuropathol (2023) 145 pp. 325-333 [ DOI: doi:10.1007/s00401-022-02533-1 Pubmed: 36611124 ]

Sample:

EMD-16023

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Amyloid-beta tetrameric filaments with the Arctic mutation (E22G) from Alzheimer's disease brains | ABeta40

Release date: Jan. 18, 2023
Resolution: 1.99 Å
EM Method: Helical reconstruction
Fitted PDBs: 8bg0
Q-score: 0.743

Yang Y, Zhang W, Murzin AG, Schweighauser M, Huang M, Lovestam S, Peak-Chew SY, Saito T, Saido TC, Macdonald J, Lavenir I, Ghetti B, Graff C, Kumar A, Nordberg A, Goedert M, Scheres SHW

Acta Neuropathol (2023) 145 pp. 325-333 [ Pubmed: 36611124 DOI: doi:10.1007/s00401-022-02533-1 ]

Sample:

Amyloid-beta precursor protein (4 kDa, Protein from human)
Water (18 Da, Ligand)
Amyloid-beta filaments extracted from the human brain with arctic mutation (e693g) of alzheimer's disease (Tissue from Homo sapiens)

EMD-16027

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Murine amyloid-beta filaments with the Arctic mutation (E22G) from APP(NL-G-F) mouse brains | ABeta

Release date: Jan. 18, 2023
Resolution: 3.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 8bg9
Q-score: 0.527

Yang Y, Zhang W, Murzin AG, Schweighauser M, Huang M, Lovestam S, Peak-Chew SY, Saito T, Saido TC, Macdonald J, Lavenir I, Ghetti B, Graff C, Kumar A, Nordberg A, Goedert M, Scheres SHW

Acta Neuropathol (2023) 145 pp. 325-333 [ DOI: doi:10.1007/s00401-022-02533-1 Pubmed: 36611124 ]

Sample:

Amyloid-beta filaments extracted from the mouse brains with app nl-g-f mutations (Tissue from Mus musculus)
Amyloid-beta protein 40 (4 kDa, Protein from house mouse)

EMD-13800

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Type I beta-amyloid 42 Filaments from Human Brain

Release date: Nov. 24, 2021
Resolution: 2.5 Å
EM Method: Helical reconstruction
Fitted PDBs: 7q4b
Q-score: 0.688

Yang Y, Arseni D, Zhang W, Huang M, Lovestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Ryskeldi-Falcon B, Scheres SHW, Goedert M

Science (2022) 375 pp. 167-172 [ DOI: doi:10.1126/science.abm7285 Pubmed: 35025654 ]

Sample:

Beta-amyloid 42 filaments extracted from the human brain with alzheimer's disease (Tissue from Homo sapiens)
Amyloid-beta precursor protein (4 kDa, Protein from Human)
Unknown atom or ion (Ligand)
Water (18 Da, Ligand)

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EMD-13809

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Type II beta-amyloid 42 Filaments from Human Brain

Release date: Nov. 24, 2021
Resolution: 2.8 Å
EM Method: Helical reconstruction
Fitted PDBs: 7q4m
Q-score: 0.631

Yang Y, Arseni D, Zhang W, Huang M, Lovestam S, Schweighauser M, Kotecha A, Murzin AG, Peak-Chew SY, Macdonald J, Lavenir I, Garringer HJ, Gelpi E, Newell KL, Kovacs GG, Vidal R, Ghetti B, Ryskeldi-Falcon B, Scheres SHW, Goedert M

Science (2022) 375 pp. 167-172 [ DOI: doi:10.1126/science.abm7285 Pubmed: 35025654 ]

Sample:

Beta-amyloid 42 filaments extracted from the human brain with alzheimer's disease (Tissue from Homo sapiens)
Amyloid-beta precursor protein (4 kDa, Protein from Human)
Unknown atom or ion (Ligand)

Sort by: Download

Showing 1 - 5 of 5. Page 1 of 1

Display: Statistics

Download

Select database:

EMDB [5]

Format:

Select the script type:

Shell (Unix-based) Batch (Windows-based)

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