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EMBL

was set up in 1974 as Europe’s flagship laboratory for the life sciences – an intergovernmental organisation with more than 80 independent research groups covering the spectrum of molecular biology:

Research:

perform basic research in molecular biology

Services:

offer vital services to scientists in the member states

Training

scientists, students and visitors at all levels

Transfer

and development of technology

Develop

new instruments and methods

Integrating

life science research in Europe

More about EMBL

Six sites

represent EMBL in Europe.

Barcelona

Tissue biology and disease modelling

Grenoble

Structural biology

Hamburg

Structural biology

Heidelberg

Main laboratory

Hinxton

EMBL-EBI: European Bioinformatics Institute

Rome

Epigenetics and neurobiology

Edit your search query here and hit Return to execute it:

author:"Yu Z" AND assembly_molecular_weight:{2000000 TO 5000000] AND author_orcid:"0000-0002-4120-104x"

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EMD-31112

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p53-bound TFIID-based holo PIC on HDM2 promoter

Release date: May 12, 2021
Resolution: 3.9 Å
EM Method: Single-particle
Fitted PDBs: 7egc
Q-score: 0.051

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ DOI: doi:10.1126/science.aba8490 Pubmed: 33795473 ]

Sample:

Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Pig)
Rna polymerase ii (Complex from Sus scrofa)
Dna (71-mer) (21 kDa, DNA from Homo sapiens)
Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
Rpb12 (7 kDa, Protein from Pig)
Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Pig)
General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
P53-bound tfiid-based holo pic on hdm2 promoter (Complex)
Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
Cyclin-dependent kinase 7 (39 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit rpb1 (217 kDa, Protein from Human)
General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
Cyclin-h (37 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Pig)
Cdk-activating kinase assembly factor mat1 (35 kDa, Protein from Homo sapiens)
Rpb10 (7 kDa, Protein from Pig)
Tfiih (Complex)
Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
General transcription factor iih subunit 1 (62 kDa, Protein from Homo sapiens)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
General transcription and dna repair factor iih helicase subunit xpb (89 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 4 (52 kDa, Protein from Homo sapiens)
Dna (71-mer) (22 kDa, DNA from Homo sapiens)
Tfiib (Complex from Homo sapiens)
Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Pig)
Dna(hdm2 promoters) (Complex)
Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)
General transcription and dna repair factor iih helicase subunit xpd (87 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Pig)
General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Pig)
General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)
Tfiid (Complex from Homo sapiens)
Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase subunit beta (134 kDa, Protein from Pig)
Tfiif (Complex from Homo sapiens)
General transcription factor iih subunit 2 (44 kDa, Protein from Homo sapiens)
Tfiia (Complex from Homo sapiens)

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EMD-31075

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p53-bound TFIID-based core PIC on HDM2 promoter

Release date: May 5, 2021
Resolution: 4.5 Å
EM Method: Single-particle
Fitted PDBs: 7edx
Q-score: 0.13

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ DOI: doi:10.1126/science.aba8490 Pubmed: 33795473 ]

Sample:

Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
Dna (84-mer) (26 kDa, DNA from Homo sapiens)
Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Sus scrofa)
Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Sus scrofa)
Rna polymerase ii (Complex from Sus scrofa)
Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
Tfiid (Complex from Homo sapiens)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
Rpb10 (7 kDa, Protein from Sus scrofa)
Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Sus scrofa)
Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
Dna(scp promoters) (Complex)
Zinc ion (65 Da, Ligand)
Dna (84-mer) (25 kDa, DNA from Homo sapiens)
Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Sus scrofa)
Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
Rpb1 (217 kDa, Protein from Sus scrofa)
Dna-directed rna polymerase subunit beta (134 kDa, Protein from Sus scrofa)
Tfiib (Complex from Homo sapiens)
Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Sus scrofa)
Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Sus scrofa)
Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Sus scrofa)
Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
P53-bound tfiid-based core pic on hdm2 promoter (Complex)
Tfiia (Complex from Homo sapiens)
Tfiif (Complex from Homo sapiens)
Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Sus scrofa)
Rpb12 (7 kDa, Protein from Sus scrofa)
Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)

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EMD-31107

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TFIID-based core PIC on SCP promoter

Release date: May 5, 2021
Resolution: 6.2 Å
EM Method: Single-particle
Fitted PDBs: 7eg7
Q-score: 0.092

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ DOI: doi:10.1126/science.aba8490 Pubmed: 33795473 ]

Sample:

Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Pig)
Rpb10 (7 kDa, Protein from Pig)
Rna polymerase ii (Complex from Sus scrofa)
Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
Tfiid (Complex from Homo sapiens)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Rpb12 (7 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Pig)
General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
Dna(scp promoters) (Complex)
Zinc ion (65 Da, Ligand)
Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Pig)
Dna (79-mer) (24 kDa, DNA from Homo sapiens)
Tfiib (Complex from Homo sapiens)
Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
Rpb1 (217 kDa, Protein from Pig)
Tfiia (Complex from Homo sapiens)
Tfiif (Complex from Homo sapiens)
Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Pig)
Dna-directed rna polymerase subunit beta (134 kDa, Protein from Pig)
Dna (79-mer) (24 kDa, DNA from Homo sapiens)
Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)
Tfiid-based core pic on scp promoter (Complex)

[Show more]

EMD-31108

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TFIID-based core PIC on PUMA promoter

Release date: May 5, 2021
Resolution: 7.4 Å
EM Method: Single-particle
Fitted PDBs: 7eg8
Q-score: 0.074

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ DOI: doi:10.1126/science.aba8490 Pubmed: 33795473 ]

Sample:

Dna (85-mer) (26 kDa, DNA from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Pig)
Rna polymerase ii (Complex from Sus scrofa)
Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
Rpb12 (7 kDa, Protein from Pig)
Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
Tfiid-based core pic on puma promoter (Complex)
Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
Rpb1 (217 kDa, Protein from Pig)
Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Pig)
Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
Dna (85-mer) (26 kDa, DNA from Homo sapiens)
Dna(scp promoters) (Complex)
Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Pig)
Rpb10 (7 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
Tfiib (Complex from Homo sapiens)
Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
Zinc ion (65 Da, Ligand)
Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Pig)
General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Pig)
Tfiid (Complex from Homo sapiens)
Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase subunit beta (134 kDa, Protein from Pig)
Tfiif (Complex from Homo sapiens)
Tfiia (Complex from Homo sapiens)

[Show more]

EMD-31109

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TFIID-based intermediate PIC on SCP promoter

Release date: May 5, 2021
Resolution: 3.7 Å
EM Method: Single-particle
Fitted PDBs: 7eg9
Q-score: 0.137

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ DOI: doi:10.1126/science.aba8490 Pubmed: 33795473 ]

Sample:

Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Pig)
Rpb10 (7 kDa, Protein from Pig)
Rna polymerase ii (Complex from Sus scrofa)
Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
Tfiid (Complex from Homo sapiens)
Tfiie (Complex)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Rpb12 (7 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Pig)
General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
Dna (79-mer) (24 kDa, DNA from Homo sapiens)
Zinc ion (65 Da, Ligand)
Tfiid-based intermediate pic on scp promoter (Complex)
Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Pig)
Dna(scp promoters) (Complex from Homo sapiens)
Tfiib (Complex from Homo sapiens)
Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
Rpb1 (217 kDa, Protein from Pig)
Tfiia (Complex from Homo sapiens)
Tfiif (Complex from Homo sapiens)
Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Pig)
Dna-directed rna polymerase subunit beta (134 kDa, Protein from Pig)
Dna (79-mer) (24 kDa, DNA from Homo sapiens)
Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)

[Show more]

EMD-31110

Download Map 3D View

TFIID-based intermediate PIC on PUMA promoter

Release date: May 5, 2021
Resolution: 4.1 Å
EM Method: Single-particle
Fitted PDBs: 7ega
Q-score: 0.122

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ DOI: doi:10.1126/science.aba8490 Pubmed: 33795473 ]

Sample:

Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
Rna polymerase ii (Complex from Sus scrofa)
Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
Tfiid (Complex from Homo sapiens)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
Rpb12 (7 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit f (14 kDa, Protein from Pig)
General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
Dna(puma promoters) (Complex)
Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from Pig)
Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
Dna (85-mer) (26 kDa, DNA from Homo sapiens)
Dna-directed rna polymerase subunit (167 kDa, Protein from Pig)
Rpb10 (7 kDa, Protein from Pig)
Tfiid-based intermediate pic on puma promoter (Complex)
Zinc ion (65 Da, Ligand)
Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from Pig)
Tfiie (Complex from Homo sapiens)
Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
Rna_pol_l_2 domain-containing protein (13 kDa, Protein from Pig)
Tfiib (Complex from Homo sapiens)
Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
Dna (85-mer) (26 kDa, DNA from Homo sapiens)
Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit e (24 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
Tfiia (Complex from Homo sapiens)
Tfiif (Complex from Homo sapiens)
Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from Pig)
Dna-directed rna polymerase subunit beta (134 kDa, Protein from Pig)
Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)

[Show more]

EMD-31111

Download Map 3D View

TFIID-based holo PIC on SCP promoter

Release date: May 5, 2021
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7egb
Q-score: 0.012

Chen X, Qi Y, Wu Z, Wang X, Li J, Zhao D, Hou H, Li Y, Yu Z, Liu W, Wang M, Ren Y, Li Z, Yang H, Xu Y

Science (2021) 372 [ DOI: doi:10.1126/science.aba8490 Pubmed: 33795473 ]

Sample:

Transcription initiation factor tfiid subunit 11 (23 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 13 (14 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb9 (14 kDa, Protein from pig)
Rpb10 (7 kDa, Protein from Pig)
Dna-directed rna polymerase subunit beta (134 kDa, Protein from pig)
Rna polymerase ii (Complex from Sus scrofa)
Dna-directed rna polymerase ii subunit rpb1 (217 kDa, Protein from human)
Dna (69-mer) (21 kDa, DNA from Homo sapiens)
Transcription initiation factor tfiid subunit 6 (72 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 8 (34 kDa, Protein from Homo sapiens)
Cdk-activating kinase assembly factor mat1 (35 kDa, Protein from Homo sapiens)
Tfiid (Complex from Homo sapiens)
General transcription factor iih subunit 1 (62 kDa, Protein from Homo sapiens)
General transcription factor iih subunit 3 (34 kDa, Protein from Homo sapiens)
Tata-box-binding protein (37 kDa, Protein from Homo sapiens)
General transcription factor iie subunit 1 (49 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 4 (110 kDa, Protein from Homo sapiens)
General transcription factor iif subunit 1 (58 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 2 (137 kDa, Protein from Homo sapiens)
Dna (69-mer) (29 kDa, DNA from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb3 (31 kDa, Protein from pig)
Transcription initiation factor tfiid subunit 12 (17 kDa, Protein from Homo sapiens)
Transcription initiation factor iib (34 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit rpb4 (16 kDa, Protein from pig)
General transcription factor iih subunit 2 (44 kDa, Protein from Homo sapiens)
Dna(scp promoters) (Complex)
Dna-directed rna polymerases i, ii, and iii subunit rpabc3 (17 kDa, Protein from pig)
Zinc ion (65 Da, Ligand)
General transcription and dna repair factor iih helicase subunit xpd (87 kDa, Protein from Homo sapiens)
Transcription initiation factor iia subunit 1 (41 kDa, Protein from Homo sapiens)
Tfiib (Complex from Homo sapiens)
Cyclin-dependent kinase 7 (39 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 10 (21 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 5 (86 kDa, Protein from Homo sapiens)
Magnesium ion (24 Da, Ligand)
Transcription initiation factor iie subunit beta (33 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 3 (103 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 7 (40 kDa, Protein from Homo sapiens)
Tfiih (Complex)
General transcription factor iif subunit 2 (28 kDa, Protein from Homo sapiens)
Iron/sulfur cluster (351 Da, Ligand)
Rna_pol_l_2 domain-containing protein (13 kDa, Protein from pig)
General transcription and dna repair factor iih helicase subunit xpb (89 kDa, Protein from Homo sapiens)
Tfiid-based holo pic on scp promoter (Complex)
Cyclin-h (37 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 9 (29 kDa, Protein from Homo sapiens)
Rpb12 (7 kDa, Protein from pig)
General transcription factor iih subunit 5 (8 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit e (24 kDa, Protein from pig)
Tfiia (Complex from Homo sapiens)
Tfiif (Complex from Homo sapiens)
Transcription initiation factor iia subunit 2 (12 kDa, Protein from Homo sapiens)
Dna-directed rna polymerase ii subunit f (14 kDa, Protein from pig)
Dna-directed rna polymerase ii subunit rpb7 (19 kDa, Protein from pig)
General transcription factor iih subunit 4 (52 kDa, Protein from Homo sapiens)
Transcription initiation factor tfiid subunit 1 (212 kDa, Protein from Homo sapiens)

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EMDB [7]

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