S.c. Condensin peripheral Ycg1 subcomplex bound to DNA
Resolution: 3.86 Å
EM Method: Single-particle
Fitted PDBs: 7qfw
Q-score: 0.342
Shaltiel IA, Datta S, Lecomte L, Hassler M, Kschonsak M, Bravo S, Stober C, Ormanns J, Eustermann S, Haering CH
Science (2022) 376 pp. 1087-1094 [ DOI: doi:10.1126/science.abm4012 Pubmed: 35653469 ]
- S.c. condensin peripheral ycg1 complex bound to dna (707 kDa, Complex from Saccharomyces cerevisiae)
- Synthetic dna ligand (15 kDa, DNA from synthetic construct)
- Condensin complex subunit 2 (92 kDa, Protein from Saccharomyces cerevisiae S288C)
- Condensin complex subunit 3 (117 kDa, Protein from Saccharomyces cerevisiae S288C)
- Synthetic dna ligand (15 kDa, DNA from synthetic construct)
ATP-bound AMP-activated protein kinase
Resolution: 3.93 Å
EM Method: Single-particle
Fitted PDBs: 7m74
Q-score: 0.27
Yan Y, Mukherjee S, Harikumar KG, Strutzenberg TS, Zhou XE, Suino-Powell K, Xu TH, Sheldon RD, Lamp J, Brunzelle JS, Radziwon K, Ellis A, Novick SJ, Vega IE, Jones RG, Miller LJ, Xu HE, Griffin PR, Kossiakoff AA, Melcher K
Science (2021) 373 pp. 413-419 [ DOI: doi:10.1126/science.abe7565 Pubmed: 34437114 ]
- 5'-amp-activated protein kinase subunit beta-2 (22 kDa, Protein from Homo sapiens)
- Adenosine monophosphate (347 Da, Ligand)
- Fab light chain (22 kDa, Protein from Homo sapiens)
- Nanobody (13 kDa, Protein from Lama glama)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Fab heavy chain (24 kDa, Protein from Homo sapiens)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- 5'-amp-activated protein kinase subunit gamma-1 (34 kDa, Protein from Homo sapiens)
- 6-[4-(2-piperidin-1-ylethoxy)phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine (399 Da, Ligand)
- Mbp-fused atp bound ampk in complex with c-compound stabilized by fab and a nanobody (Complex from Homo sapiens)
- Maltose/maltodextrin abc transporter substrate-binding protein male (40 kDa, Protein from Escherichia coli)
- 5'-amp-activated protein kinase catalytic subunit alpha-1 (56 kDa, Protein from Homo sapiens)
Structure of human CD19-CD81 co-receptor complex bound to coltuximab Fab fragment
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7jic
Q-score: 0.388
Susa KJ, Rawson S, Kruse AC, Blacklow SC
Science (2021) 371 pp. 300-304 [ DOI: doi:10.1126/science.abd9836 ]
- Coltuximab heavy chain (24 kDa, Protein from Mus musculus)
- Coltuximab fab fragment (Complex from Mus musculus)
- Coltuximab light chain (23 kDa, Protein from Mus musculus)
- Complex of b cell co-receptor cd19 bound to the tetraspanin cd81 and coltuximab fab fragment (110 kDa, Complex)
- B-lymphocyte antigen cd19 (36 kDa, Protein from Homo sapiens)
- B cell co-receptor cd19 bound to the tetraspanin cd81 (Complex from Homo sapiens)
- Cd81 antigen (26 kDa, Protein from Homo sapiens)