CryoEM Structure INO80core Hexasome complex composite map state1
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8oo7
Q-score: 0.556
Zhang M, Jungblut A, Kunert F, Hauptmann L, Hoffmann T, Kolesnikova O, Metzner F, Moldt M, Weis F, DiMaio F, Hopfner KP, Eustermann S
Science (2023) 381 pp. 313-319 [ DOI: doi:10.1126/science.adf6287 Pubmed: 37384673 ]
- Ino80 core module in complex with hexasome (861 kDa, Complex)
- Dna strand 2 (70 kDa, DNA from synthetic construct)
- Chromatin-remodeling complex subunit ies6 (23 kDa, Protein from Thermochaetoides thermophila)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Ino eighty subunit 2 (53 kDa, Protein from Thermochaetoides thermophila)
- Ruvb-like protein 2 (53 kDa, Protein from Thermochaetoides thermophila)
- Chromatin remodeler ino80 (Complex from Thermochaetoides thermophila)
- Histones (Complex from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Ruvb-like protein 1 (50 kDa, Protein from Thermochaetoides thermophila)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Chromatin-remodeling atpase ino80 (130 kDa, Protein from Thermochaetoides thermophila)
- Magnesium ion (24 Da, Ligand)
- Actin-related protein 5 (87 kDa, Protein from Thermochaetoides thermophila)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Dna strand 1 (69 kDa, DNA from synthetic construct)
- Histone h2a (14 kDa, Protein from Homo sapiens)
- Histone h2b (13 kDa, Protein from Homo sapiens)
- Dna (Complex from Synthetic construct)
CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state1
Resolution: 2.9 Å
EM Method: Single-particle
Fitted PDBs: 8oof
Q-score: 0.571
Zhang M, Jungblut A, Kunert F, Hauptmann L, Hoffmann T, Kolesnikova O, Metzner F, Moldt M, Weis F, DiMaio F, Hopfner KP, Eustermann S
Science (2023) 381 pp. 313-319 [ DOI: doi:10.1126/science.adf6287 Pubmed: 37384673 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Actin-related protein 5 (87 kDa, Protein from Thermochaetoides thermophila)
- Magnesium ion (24 Da, Ligand)
- Ino80 core module in complex with hexasome (861 kDa, Complex from Thermochaetoides thermophila)
- Chromatin-remodeling complex subunit ies6 (23 kDa, Protein from Thermochaetoides thermophila)
CryoEM Structure INO80core Hexasome complex Arp5 grappler refinement state1
Resolution: 5.69 Å
EM Method: Single-particle
Fitted PDBs: 8ook
Q-score: 0.251
Zhang M, Jungblut A, Kunert F, Hauptmann L, Hoffmann T, Kolesnikova O, Metzner F, Moldt M, Weis F, DiMaio F, Hopfner KP, Eustermann S
Science (2023) 381 pp. 313-319 [ DOI: doi:10.1126/science.adf6287 Pubmed: 37384673 ]
- Actin-related protein 5 (87 kDa, Protein from Thermochaetoides thermophila)
- Ino80 core module in complex with hexasome (861 kDa, Complex from Thermochaetoides thermophila)
INO80 core bound to hexasome composite map of state 2
Resolution: 2.7 Å
EM Method: Single-particle
Fitted PDBs: 8oop
Q-score: 0.554
Zhang M, Jungblut A, Kunert F, Hauptmann L, Hoffmann T, Kolesnikova O, Metzner F, Moldt M, Weis F, DiMaio F, Hopfner KP, Eustermann S
Science (2023) 381 pp. 313-319 [ DOI: doi:10.1126/science.adf6287 Pubmed: 37384673 ]
- Ino80 core module in complex with hexasome (861 kDa, Complex)
- Dna strand 2 (70 kDa, DNA from synthetic construct)
- Chromatin-remodeling complex subunit ies6 (23 kDa, Protein from Thermochaetoides thermophila)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Histone h4 (11 kDa, Protein from Homo sapiens)
- Ino eighty subunit 2 (53 kDa, Protein from Thermochaetoides thermophila)
- Ruvb-like protein 2 (53 kDa, Protein from Thermochaetoides thermophila)
- Chromatin remodeler ino80 (Complex from Thermochaetoides thermophila)
- Histones (Complex from Homo sapiens)
- Histone h3.1 (15 kDa, Protein from Homo sapiens)
- Ruvb-like protein 1 (50 kDa, Protein from Thermochaetoides thermophila)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Chromatin-remodeling atpase ino80 (130 kDa, Protein from Thermochaetoides thermophila)
- Dna strand 1 (69 kDa, DNA from synthetic construct)
- Magnesium ion (24 Da, Ligand)
- Actin-related protein 5 (87 kDa, Protein from Thermochaetoides thermophila)
- Tetrafluoroaluminate ion (102 Da, Ligand)
- Histone h2a (14 kDa, Protein from Homo sapiens)
- Histone h2b (13 kDa, Protein from Homo sapiens)
- Dna (Complex from Synthetic construct)
CryoEM Structure INO80core Hexasome complex Rvb core refinement state2
Resolution: 2.87 Å
EM Method: Single-particle
Fitted PDBs: 8oor
Q-score: 0.597
Zhang M, Jungblut A, Kunert F, Hauptmann L, Hoffmann T, Kolesnikova O, Metzner F, Moldt M, Weis F, DiMaio F, Hopfner KP, Eustermann S
Science (2023) 381 pp. 313-319 [ DOI: doi:10.1126/science.adf6287 Pubmed: 37384673 ]
- Ino eighty subunit 2 (53 kDa, Protein from Thermochaetoides thermophila)
- Ruvb-like protein 2 (53 kDa, Protein from Thermochaetoides thermophila)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Chromatin-remodeling atpase ino80 (130 kDa, Protein from Thermochaetoides thermophila)
- Chromatin-remodeling complex subunit ies6 (23 kDa, Protein from Thermochaetoides thermophila)
- Ino80 core module in complex with hexasome (861 kDa, Complex from Thermochaetoides thermophila)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Ruvb-like protein 1 (50 kDa, Protein from Thermochaetoides thermophila)
- Actin-related protein 5 (87 kDa, Protein from Thermochaetoides thermophila)
CryoEM Structure INO80core Hexasome complex Arp5 Ies6 refinement state2
Resolution: 2.85 Å
EM Method: Single-particle
Fitted PDBs: 8oot
Q-score: 0.552
Zhang M, Jungblut A, Kunert F, Hauptmann L, Hoffmann T, Kolesnikova O, Metzner F, Moldt M, Weis F, DiMaio F, Hopfner KP, Eustermann S
Science (2023) 381 pp. 313-319 [ DOI: doi:10.1126/science.adf6287 Pubmed: 37384673 ]
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Actin-related protein 5 (87 kDa, Protein from Thermochaetoides thermophila)
- Magnesium ion (24 Da, Ligand)
- Arp6-ies6 of ino80 complex (Complex from Thermochaetoides thermophila)
- Chromatin-remodeling complex subunit ies6 (23 kDa, Protein from Thermochaetoides thermophila)
- Ino80 core module in complex with hexasome (861 kDa, Complex)
Class1 of the INO80-Hexasome complex
Resolution: 3.04 Å
EM Method: Single-particle
Fitted PDBs: 8ets
Q-score: 0.473
Wu H, Munoz EN, Hsieh LJ, Chio US, Gourdet MA, Narlikar GJ, Cheng Y
Science (2023) 381 pp. 319-324 [ DOI: doi:10.1126/science.adf4197 Pubmed: 37384669 ]
- Actin-related protein 5 (86 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ruvb-like protein 2 (50 kDa, Protein from Saccharomyces cerevisiae S288C)
- Chromatin-remodeling atpase ino80 (54 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ino80-hex (Complex from Saccharomyces cerevisiae)
- Ruvb-like protein 1 (48 kDa, Protein from Saccharomyces cerevisiae S288C)
- Chromatin-remodeling complex subunit ies6 (15 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ino eighty subunit 2 (3 kDa, Protein from Saccharomyces cerevisiae S288C)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Class2 of the INO80-Hexasome complex
Resolution: 2.8 Å
EM Method: Single-particle
Fitted PDBs: 8etu
Q-score: 0.512
Wu H, Munoz EN, Hsieh LJ, Chio US, Gourdet MA, Narlikar GJ, Cheng Y
Science (2023) 381 pp. 319-324 [ DOI: doi:10.1126/science.adf4197 Pubmed: 37384669 ]
- Actin-related protein 5 (86 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ruvb-like protein 2 (50 kDa, Protein from Saccharomyces cerevisiae S288C)
- Chromatin-remodeling atpase ino80 (54 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ino80-hex (Complex from Saccharomyces cerevisiae)
- Ruvb-like protein 1 (48 kDa, Protein from Saccharomyces cerevisiae S288C)
- Chromatin-remodeling complex subunit ies6 (15 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ino eighty subunit 2 (3 kDa, Protein from Saccharomyces cerevisiae S288C)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Class3 of INO80-Hexasome complex
Resolution: 2.64 Å
EM Method: Single-particle
Fitted PDBs: 8etw
Q-score: 0.542
Wu H, Munoz EN, Hsieh LJ, Chio US, Gourdet MA, Narlikar GJ, Cheng Y
Science (2023) 381 pp. 319-324 [ DOI: doi:10.1126/science.adf4197 Pubmed: 37384669 ]
- Actin-related protein 5 (86 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ruvb-like protein 2 (50 kDa, Protein from Saccharomyces cerevisiae S288C)
- Chromatin-remodeling atpase ino80 (54 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ino80-hex (Complex from Saccharomyces cerevisiae)
- Ruvb-like protein 1 (48 kDa, Protein from Saccharomyces cerevisiae S288C)
- Chromatin-remodeling complex subunit ies6 (15 kDa, Protein from Saccharomyces cerevisiae S288C)
- Ino eighty subunit 2 (3 kDa, Protein from Saccharomyces cerevisiae S288C)
- Adenosine-5'-diphosphate (427 Da, Ligand)
Class1 of the INO80-Nucleosome complex
Resolution: 3.48 Å
EM Method: Single-particle
Fitted PDBs: 8eu9
Q-score: 0.368
Wu H, Munoz EN, Hsieh LJ, Chio US, Gourdet MA, Narlikar GJ, Cheng Y
Science (2023) 381 pp. 319-324 [ Pubmed: 37384669 DOI: doi:10.1126/science.adf4197 ]
- Chromatin-remodeling complex subunit ies6 (15 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ruvb-like protein 2 (49 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Actin-related protein 5 (87 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ino eighty subunit 2 (3 kDa, Protein from Saccharomyces cerevisiae S288C)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Ruvb-like protein 1 (48 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))
- Ino80-ncp (Complex from Saccharomyces cerevisiae)
- Chromatin-remodeling atpase ino80 (56 kDa, Protein from Saccharomyces cerevisiae (strain ATCC 204508 / S288c))