human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7
Resolution: 3.03 Å
EM Method: Single-particle
Fitted PDBs: 8pk0
Q-score: 0.455
Nat Commun (2023) 14 pp. 7991-7991 [ Pubmed: 38042949 DOI: doi:10.1038/s41467-023-43599-z ]
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
- Mitochondrial ribosome-associated gtpase 1 (37 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
- S-(2-{[n-(2-hydroxy-4-{[hydroxy(oxido)phosphino]oxy}-3,3-dimethylbutanoyl)-beta-alanyl]amino}ethyl) decanethioate (496 Da, Ligand)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
- 5-methylcytosine rrna methyltransferase nsun4 (43 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
- Large mitoribosomal subunit biogenesis intermediate with gtpbp10, gtpbp7, nsun4-mterf4, acp-module (1 MDa, Complex from Homo sapiens)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
- Cp trna-val (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
- Gtp-binding protein 10 (42 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
- Phosphoaminophosphonic acid-guanylate ester (522 Da, Ligand)
- Large ribosomal subunit protein ml43 (23 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
- Transcription termination factor 4, mitochondrial (44 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
- S-adenosylmethionine (398 Da, Ligand)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
- 16s rrna + pre-h68-71 segment (509 kDa, RNA from Homo sapiens)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Homo sapiens)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
Resolution: 2.56 Å
EM Method: Single-particle
Fitted PDBs: 7po4
Q-score: 0.595
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I, Sergiev P, Rorbach J, Amunts A
Nature (2022) 606 pp. 603-608 [ Pubmed: 35676484 DOI: doi:10.1038/s41586-022-04795-x ]
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Homo sapiens)
- Potassium ion (39 Da, Ligand)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
- Water (18 Da, Ligand)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
- Assembly intermediate of the large subunit of human mitochondrial ribosome (Complex from Homo sapiens)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Homo sapiens)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- Trnaval (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Homo sapiens)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
- 16srrna (500 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l12, mitochondrial (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4
Resolution: 2.89 Å
EM Method: Single-particle
Fitted PDBs: 7qh7
Q-score: 0.441
Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A, Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren AJ, Minczuk M
Nat Commun (2022) 13 pp. 929-929 [ Pubmed: 35177605 DOI: doi:10.1038/s41467-022-28503-5 ]
- Peptidyl-trna hydrolase ict1, mitochondrial (14 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l23, mitochondrial (14 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (5 kDa, Protein from human)
- 39s ribosomal protein l30, mitochondrial (13 kDa, Protein from human)
- 39s ribosomal protein l38, mitochondrial (34 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (19 kDa, Protein from human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from human)
- 39s ribosomal protein l45, mitochondrial (19 kDa, Protein from human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (11 kDa, Protein from human)
- 39s ribosomal protein l41, mitochondrial (14 kDa, Protein from human)
- 39s ribosomal protein l50, mitochondrial (12 kDa, Protein from human)
- 39s ribosomal protein l15, mitochondrial (32 kDa, Protein from human)
- Ribosomal protein 63, mitochondrial (9 kDa, Protein from human)
- 39s ribosomal protein l34, mitochondrial (5 kDa, Protein from human)
- Magnesium ion (24 Da, Ligand)
- Mitochondrial trnaval (19 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l19, mitochondrial (25 kDa, Protein from human)
- 39s ribosomal protein l18, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein s18a, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein l27, mitochondrial (11 kDa, Protein from human)
- 39s ribosomal protein l9, mitochondrial (11 kDa, Protein from human)
- 39s ribosomal protein l42, mitochondrial (9 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l2, mitochondrial (23 kDa, Protein from human)
- 39s ribosomal protein l17, mitochondrial (17 kDa, Protein from human)
- 39s ribosomal protein l36, mitochondrial (4 kDa, Protein from human)
- 39s ribosomal protein l37, mitochondrial (45 kDa, Protein from human)
- 39s ribosomal protein l32, mitochondrial (12 kDa, Protein from human)
- 39s ribosomal protein l20, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein l48, mitochondrial (2 kDa, Protein from Homo sapiens)
- Mitochondrial assembly of ribosomal large subunit protein 1 (13 kDa, Protein from human)
- 39s ribosomal protein s30, mitochondrial (45 kDa, Protein from human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from human)
- 39s ribosomal protein l21, mitochondrial (17 kDa, Protein from human)
- Acyl carrier protein, mitochondrial (9 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein l14, mitochondrial (12 kDa, Protein from human)
- 39s ribosomal protein l49, mitochondrial (15 kDa, Protein from human)
- 16s ribosomal rna (403 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l35, mitochondrial (11 kDa, Protein from human)
- 39s ribosomal protein l10, mitochondrial (3 kDa, Protein from human)
- 39s ribosomal protein l28, mitochondrial (28 kDa, Protein from human)
- 39s ribosomal protein l44, mitochondrial (32 kDa, Protein from human)
- 39s ribosomal protein l47, mitochondrial (21 kDa, Protein from human)
- 39s ribosomal protein l52, mitochondrial (9 kDa, Protein from human)
- 39s ribosomal protein l4, mitochondrial (28 kDa, Protein from human)
- 39s ribosomal protein l51, mitochondrial (11 kDa, Protein from human)
- Water (18 Da, Ligand)
- 39s ribosomal protein l16, mitochondrial (23 kDa, Protein from human)
- 39s ribosomal protein l39, mitochondrial (33 kDa, Protein from human)
- 39s ribosomal protein l43, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein l24, mitochondrial (5 kDa, Protein from human)
- Human mitochondrial ribosome large subunit (Complex from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (34 kDa, Protein from human)
Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1
Resolution: 3.08 Å
EM Method: Single-particle
Fitted PDBs: 7qh6
Q-score: 0.374
Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A, Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren AJ, Minczuk M
Nat Commun (2022) 13 pp. 929-929 [ Pubmed: 35177605 DOI: doi:10.1038/s41467-022-28503-5 ]
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from human)
- Human mitochondrial ribosome large subunit (Complex from Homo sapiens)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from human)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from human)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from human)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from human)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from human)
- 16s ribosomal rna (500 kDa, RNA from human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from human)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from human)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from human)
- Mitochondrial trnaval (22 kDa, RNA from human)
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7pd3
Q-score: 0.394
Chandrasekaran V, Desai N, Burton NO, Yang H, Price J, Miska EA, Ramakrishnan V
eLife (2021) 10 [ Pubmed: 34609277 DOI: doi:10.7554/eLife.68806 ]
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 16s rrna (500 kDa, RNA from Human)
- S-adenosylmethionine (398 Da, Ligand)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- Uridine-5'-monophosphate (324 Da, Ligand)
- Cytidine-5'-monophosphate (323 Da, Ligand)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- Guanosine-5'-monophosphate (363 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- Adenosine-5'-monophosphate (347 Da, Ligand)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
- Transcription termination factor 4, mitochondrial (44 kDa, Protein from Human)
- Phosphomethylphosphonic acid guanylate ester (521 Da, Ligand)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- Mitochondrial ribosome-associated gtpase 1 (37 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- Mt-trnaval (22 kDa, RNA from Human)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 4'-phosphopantetheine (358 Da, Ligand)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- Pseudouridine-5'-monophosphate (324 Da, Ligand)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 5-methylcytosine rrna methyltransferase nsun4 (43 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- Human mitoribosomal large subunit assembly intermediate (Complex from Homo sapiens)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- Ml65 (2 kDa, Protein from Human)
- O2'-methylguanosine-5'-monophosphate (377 Da, Ligand)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 1
Resolution: 5.7 Å
EM Method: Single-particle
Fitted PDBs: 7oi6
Q-score: 0.28
Cheng J, Berninghausen O, Beckmann R
Nat Commun (2021) 12 pp. 4544-4544 [ DOI: doi:10.1038/s41467-021-24818-x Pubmed: 34315873 ]
- Mitochondrial val trna (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Homo sapiens)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Homo sapiens)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Homo sapiens)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Homo sapiens)
- 16s rrna (500 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Homo sapiens)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Homo sapiens)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Homo sapiens)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Homo sapiens)
- Rrna methyltransferase 3, mitochondrial (47 kDa, Protein from Homo sapiens)
- Gtp-binding protein 10 (42 kDa, Protein from Homo sapiens)
- Human 39s mitoribosome assembly intermediates, state 1 (Complex from Homo sapiens)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Homo sapiens)
- 4'-phosphopantetheine (358 Da, Ligand)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Homo sapiens)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Homo sapiens)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Homo sapiens)
- Probable atp-dependent rna helicase ddx28 (59 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Homo sapiens)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Homo sapiens)
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7oi7
Q-score: 0.4
Cheng J, Berninghausen O, Beckmann R
Nat Commun (2021) 12 pp. 4544-4544 [ DOI: doi:10.1038/s41467-021-24818-x Pubmed: 34315873 ]
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- Human 39s mitoribosome assembly intermediates, state 2 (Complex from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Human)
- 16s rrna (500 kDa, RNA from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- Mitochondrial val trna (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- 4'-phosphopantetheine (358 Da, Ligand)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3A
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 7oi8
Q-score: 0.458
Cheng J, Berninghausen O, Beckmann R
Nat Commun (2021) 12 pp. 4544-4544 [ DOI: doi:10.1038/s41467-021-24818-x Pubmed: 34315873 ]
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- Mitochondrial trna (23 kDa, RNA from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- Human 39s mitoribosome assembly intermediates, state 3a (Complex from Homo sapiens)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Human)
- 16s rrna (500 kDa, RNA from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- Mitochondrial val trna (22 kDa, RNA from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- 4'-phosphopantetheine (358 Da, Ligand)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B
Resolution: 3.3 Å
EM Method: Single-particle
Fitted PDBs: 7oi9
Q-score: 0.409
Cheng J, Berninghausen O, Beckmann R
Nat Commun (2021) 12 pp. 4544-4544 [ DOI: doi:10.1038/s41467-021-24818-x Pubmed: 34315873 ]
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- Human 39s mitoribosome assembly intermediates, state 3b (Complex from Homo sapiens)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 4'-phosphopantetheine (358 Da, Ligand)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- Mitochondrial val trna (22 kDa, RNA from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 16s rrna (500 kDa, RNA from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Human)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7oic
Q-score: 0.501
Cheng J, Berninghausen O, Beckmann R
Nat Commun (2021) 12 pp. 4544-4544 [ DOI: doi:10.1038/s41467-021-24818-x Pubmed: 34315873 ]
- 39s ribosomal protein l52, mitochondrial (13 kDa, Protein from Human)
- Ribosomal protein 63, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l53, mitochondrial (12 kDa, Protein from Human)
- 39s ribosomal protein l49, mitochondrial (19 kDa, Protein from Human)
- 39s ribosomal protein l30, mitochondrial (18 kDa, Protein from Human)
- Human 39s mitoribosome assembly intermediates, state 4 (Complex from Homo sapiens)
- 39s ribosomal protein l11, mitochondrial (20 kDa, Protein from Human)
- Growth arrest and dna damage-inducible proteins-interacting protein 1 (25 kDa, Protein from Human)
- 39s ribosomal protein l32, mitochondrial (21 kDa, Protein from Human)
- 39s ribosomal protein l4, mitochondrial (34 kDa, Protein from Human)
- Acyl carrier protein, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l38, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l36, mitochondrial (11 kDa, Protein from Human)
- 39s ribosomal protein l21, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l34, mitochondrial (10 kDa, Protein from Human)
- 39s ribosomal protein l39, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l51, mitochondrial (15 kDa, Protein from Human)
- S-adenosylmethionine (398 Da, Ligand)
- 39s ribosomal protein l33, mitochondrial (7 kDa, Protein from Human)
- 39s ribosomal protein l55, mitochondrial (15 kDa, Protein from Human)
- Mief1 upstream open reading frame protein (8 kDa, Protein from Human)
- 39s ribosomal protein l45, mitochondrial (35 kDa, Protein from Human)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Human)
- Cytidine-5'-monophosphate (323 Da, Ligand)
- 39s ribosomal protein l17, mitochondrial (20 kDa, Protein from Human)
- Zinc ion (65 Da, Ligand)
- 16s rrna (500 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l54, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein s18a, mitochondrial (22 kDa, Protein from Human)
- 39s ribosomal protein l24, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l43, mitochondrial (23 kDa, Protein from Human)
- 5-methylcytosine rrna methyltransferase nsun4 (43 kDa, Protein from Human)
- 39s ribosomal protein l46, mitochondrial (31 kDa, Protein from Human)
- 39s ribosomal protein l40, mitochondrial (24 kDa, Protein from Human)
- 39s ribosomal protein l2, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l10, mitochondrial (29 kDa, Protein from Human)
- Mitochondrial val trna (22 kDa, RNA from Homo sapiens)
- 39s ribosomal protein l3, mitochondrial (38 kDa, Protein from Human)
- 39s ribosomal protein l28, mitochondrial (30 kDa, Protein from Human)
- 39s ribosomal protein l48, mitochondrial (23 kDa, Protein from Human)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l13, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l9, mitochondrial (30 kDa, Protein from Human)
- Mitochondrial assembly of ribosomal large subunit protein 1 (26 kDa, Protein from Human)
- 39s ribosomal protein l44, mitochondrial (37 kDa, Protein from Human)
- 39s ribosomal protein s30, mitochondrial (50 kDa, Protein from Human)
- 39s ribosomal protein l18, mitochondrial (20 kDa, Protein from Human)
- 39s ribosomal protein l42, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l14, mitochondrial (15 kDa, Protein from Human)
- 39s ribosomal protein l19, mitochondrial (33 kDa, Protein from Human)
- 39s ribosomal protein l22, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l20, mitochondrial (17 kDa, Protein from Human)
- 39s ribosomal protein l27, mitochondrial (16 kDa, Protein from Human)
- 39s ribosomal protein l50, mitochondrial (18 kDa, Protein from Human)
- 39s ribosomal protein l16, mitochondrial (28 kDa, Protein from Human)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Human)
- 4'-phosphopantetheine (358 Da, Ligand)
- Peptidyl-trna hydrolase ict1, mitochondrial (23 kDa, Protein from Human)
- 39s ribosomal protein l37, mitochondrial (48 kDa, Protein from Human)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Human)
- Transcription termination factor 4, mitochondrial (44 kDa, Protein from Human)
- 39s ribosomal protein l47, mitochondrial (29 kDa, Protein from Human)
- Adenosine-5'-monophosphate (347 Da, Ligand)