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sample_name:"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1" AND resolution:[3 TO 4} AND xref_links:"interpro" AND author_name:"Yang M"
Active state CI from Q10-NADH dataset, Subclass 2
Release date: March 22, 2023
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7w0y
Q-score: 0.523
Resolution: 3.4 Å
EM Method: Single-particle
Fitted PDBs: 7w0y
Q-score: 0.523
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 (12 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from pig)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Complex i-b18 (15 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (9 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (16 kDa, Protein from pig)
Deactive state CI from Rotenone-NADH dataset, Subclass 2
Release date: Feb. 1, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w2l
Q-score: 0.57
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w2l
Q-score: 0.57
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (15 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Complex i-aggg (8 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- Complex i-kfyi (4 kDa, Protein from pig)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-sgdh (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)
Deactive state CI from DQ-NADH dataset, Subclass 1
Release date: Feb. 1, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7w31
Q-score: 0.509
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7w31
Q-score: 0.509
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex i-aggg (8 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (15 kDa, Protein from pig)
- Complex i-sgdh (16 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)
Deactive state CI from DQ-NADH dataset, Subclass 3
Release date: Feb. 1, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w35
Q-score: 0.559
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w35
Q-score: 0.559
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex i-aggg (8 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (15 kDa, Protein from pig)
- Complex i-sgdh (16 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)
Active state CI from Q1-NADH dataset, Subclass 2
Release date: Feb. 1, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w4d
Q-score: 0.587
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w4d
Q-score: 0.587
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Complex i-aggg (8 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (15 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Complex i-sgdh (16 kDa, Protein from pig)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Ubiquinone-1 (250 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Respiratory complex i (Complex from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
Active state CI from Q1-NADH dataset, Subclass 3
Release date: Feb. 1, 2023
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w4e
Q-score: 0.579
Resolution: 3.0 Å
EM Method: Single-particle
Fitted PDBs: 7w4e
Q-score: 0.579
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex i-aggg (8 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (15 kDa, Protein from pig)
- Complex i-sgdh (16 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)
- Ubiquinone-1 (250 Da, Ligand)
Active state CI from Q1-NADH dataset, Subclass 5
Release date: Jan. 25, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7w4g
Q-score: 0.574
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7w4g
Q-score: 0.574
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex i-aggg (8 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Complex i-b18 (15 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-sgdh (16 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)
- Ubiquinone-1 (250 Da, Ligand)
Deactive state CI from Q1-NADH dataset, Subclass 1
Release date: Jan. 25, 2023
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7w4j
Q-score: 0.548
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7w4j
Q-score: 0.548
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex i-aggg (8 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Complex i-b18 (15 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-sgdh (16 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)
Deactive state CI from Q1-NADH dataset, Subclass 2
Release date: Jan. 25, 2023
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7w4k
Q-score: 0.531
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7w4k
Q-score: 0.531
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex i-aggg (8 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Complex i-b18 (15 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-sgdh (16 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)
Deactive state CI from Q1-NADH dataset, Subclass 3
Release date: Jan. 25, 2023
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7w4l
Q-score: 0.565
Resolution: 3.1 Å
EM Method: Single-particle
Fitted PDBs: 7w4l
Q-score: 0.565
Gu J, Liu T, Guo R, Zhang L, Yang M
Nat Struct Mol Biol (2022) 29 pp. 172-182 [ DOI: doi:10.1038/s41594-022-00722-w Pubmed: 35145322 ]
Sample:
- Nadh dehydrogenase ubiquinone 1 alpha subcomplex subunit 9, mitochondrial (38 kDa, Protein from pig)
- Complex i-49kd (49 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from pig)
- Complex i-30kd (24 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (17 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from pig)
- Cardiolipin (1 kDa, Ligand)
- S-[2-({n-[(2r)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate (540 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (13 kDa, Protein from pig)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Complex i-aggg (8 kDa, Protein from pig)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Respiratory complex i (Complex from Sus scrofa)
- (9r,11s)-9-({[(1s)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol (767 Da, Ligand)
- Complex i-b14.5a (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (23 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (20 kDa, Protein from pig)
- Complex i-b18 (15 kDa, Protein from pig)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (14 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (9 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (19 kDa, Protein from pig)
- Complex i-b16.6 (16 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from pig)
- Complex i subunit b13 (12 kDa, Protein from pig)
- Complex i-9kd (5 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (18 kDa, Protein from pig)
- 1,4-dihydronicotinamide adenine dinucleotide (665 Da, Ligand)
- Magnesium ion (24 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (75 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from pig)
- Iron/sulfur cluster (351 Da, Ligand)
- 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (744 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from pig)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Complex i-sgdh (16 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 3 (12 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 (6 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (12 kDa, Protein from Pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from pig)
- Complex i-b17 (15 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from pig)
- Acyl carrier protein (10 kDa, Protein from pig)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from pig)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (47 kDa, Protein from pig)
- Flavin mononucleotide (456 Da, Ligand)
- Coenzyme q10, (2z,6e,10z,14e,18e,22e,26z)-isomer (863 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (36 kDa, Protein from pig)
- Complex i-b12 (9 kDa, Protein from pig)