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sample_name:"NADH-ubiquinone oxidoreductase chain 3" AND xref_links:"chebi" AND software_ft:"CRYOSPARC"
Cryo-EM structure of Tetrahymena thermophila respiratory mega-complex MC IV2+(I+III2+II)2
Release date: June 14, 2023
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8gym
Q-score: 0.556
Resolution: 2.96 Å
EM Method: Single-particle
Fitted PDBs: 8gym
Q-score: 0.556
Han F, Hu Y, Wu M, He Z, Tian H, Zhou L
Nat Commun (2023) 14 pp. 2542-2542 [ Pubmed: 37248254 DOI: doi:10.1038/s41467-023-38158-5 ]
Sample:
- Ribosomal protein l51/s25/ci-b8 domain protein (12 kDa, Protein from Tetrahymena thermophila SB210)
- Peptidase m16 inactive domain protein (58 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (21 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 7 (51 kDa, Protein from Tetrahymena thermophila SB210)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Ymf58 (13 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf65 (43 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (23 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (28 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt16 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome protein c1 (37 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (14 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (13 kDa, Protein from Tetrahymena thermophila SB210)
- Atp synthase subunit e, mitochondrial (11 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf68 (72 kDa, Protein from Tetrahymena thermophila SB210)
- 1,2-dilauroyl-sn-glycero-3-phosphate (535 Da, Ligand)
- Transmembrane protein, putative (57 kDa, Protein from Tetrahymena thermophila SB210)
- Ph domain-containing protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase complex i, 21 kda subunit (17 kDa, Protein from Tetrahymena thermophila SB210)
- Uqcrtt2 (4 kDa, Protein from Tetrahymena thermophila SB210)
- Etc complex i subunit motif protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (18 kDa, Protein from Tetrahymena thermophila SB210)
- Diphthamide synthesis protein (22 kDa, Protein from Tetrahymena thermophila SB210)
- Oxoglutarate/malate translocator protein, putative (40 kDa, Protein from Tetrahymena thermophila SB210)
- Cullin domain-containing protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Ctf/nf-i domain-containing protein (116 kDa, Protein from Tetrahymena thermophila SB210)
- Dnaj domain protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Ndub10 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Unknown peptide (7 kDa, Protein from Tetrahymena thermophila SB210)
- Heme-a (852 Da, Ligand)
- M16 family peptidase, putative (53 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila SB210)
- 39s ribosomal protein l9, mitochondrial (27 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 75 kda subunit (80 kDa, Protein from Tetrahymena thermophila SB210)
- Phage protein (14 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Zf-tim10_ddp domain-containing protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf70 (10 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt15 (27 kDa, Protein from Tetrahymena thermophila SB210)
- Carrier protein (37 kDa, Protein from Tetrahymena thermophila SB210)
- 2 iron, 2 sulfur cluster-binding protein (19 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 24 kda subunit (31 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (52 kDa, Protein from Tetrahymena thermophila SB210)
- Tetrahymena thermophila respiratory mega-complex mc (iv2+i+iii2+ii)2 (8 MDa, Complex from Tetrahymena thermophila SB210)
- Ndub4 (17 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Lipid-a-disaccharide synthase (59 kDa, Protein from Tetrahymena thermophila SB210)
- Fe3-s4 cluster (295 Da, Ligand)
- Nad-dependent epimerase/dehydratase family protein (41 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 1 (7 kDa, Protein from Tetrahymena thermophila SB210)
- Structural protein (27 kDa, Protein from Tetrahymena thermophila SB210)
- Chromosome condensation regulator rcc1 repeat protein (50 kDa, Protein from Tetrahymena thermophila SB210)
- Sdhtt3 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, mitochondrial (37 kDa, Protein from Tetrahymena thermophila SB210)
- Cox assembly mitochondrial protein (17 kDa, Protein from Tetrahymena thermophila SB210)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (70 kDa, Protein from Tetrahymena thermophila SB210)
- Heme c (618 Da, Ligand)
- Mobilization protein (23 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila SB210)
- Succinate dehydrogenase (quinone) (36 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein (20 kDa, Protein from Tetrahymena thermophila SB210)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Cytochrome b-c1 complex subunit 8 (7 kDa, Protein from Tetrahymena thermophila SB210)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Nadh dehydrogenase subunit 5 (88 kDa, Protein from Tetrahymena thermophila SB210)
- Cx9c domain-containing protein (28 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 10 (18 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt10 (28 kDa, Protein from Tetrahymena thermophila SB210)
- Gram domain protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (16 kDa, Protein from Tetrahymena thermophila SB210)
- Complex iii subunit vii (19 kDa, Protein from Tetrahymena thermophila SB210)
- Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c (26 kDa, Protein from Tetrahymena thermophila SB210)
- Sdhd (5 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 2 (20 kDa, Protein from Tetrahymena thermophila SB210)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Transcription factor apfi protein, putative (39 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 1 (32 kDa, Protein from Tetrahymena thermophila SB210)
- Transposase (8 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Surf1-like protein (35 kDa, Protein from Tetrahymena thermophila SB210)
- 2-oxoglutarate/malate carrier protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (7 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf75 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (35 kDa, Protein from Tetrahymena thermophila SB210)
- Trab family protein (45 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt22 (17 kDa, Protein from Tetrahymena thermophila SB210)
- Cardiolipin (1 kDa, Ligand)
- Transmembrane protein, putative (12 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 4 (58 kDa, Protein from Tetrahymena thermophila SB210)
- Unknown peptide (1 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (28 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase, putative (20 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (14 kDa, Protein from Tetrahymena thermophila SB210)
- 37s ribosomal protein s25, mitochondrial (33 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (7 kDa, Protein from Tetrahymena thermophila SB210)
- Tim10/ddp family zinc finger protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nduph2 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Annexin (8 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt9 (29 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Iron/sulfur cluster (351 Da, Ligand)
- Transposase (11 kDa, Protein from Tetrahymena thermophila SB210)
- Rnase iii domain-containing protein (35 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt3 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl-coa synthetase (amp-forming)/amp-acid ligase ii (36 kDa, Protein from Tetrahymena thermophila SB210)
- Zinc ion (65 Da, Ligand)
- Coxtt28 (11 kDa, Protein from Tetrahymena thermophila SB210)
- Zf-tim10_ddp domain-containing protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Phosphatidylinositol (887 Da, Ligand)
- Ndub2 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Iron-binding zinc finger cdgsh type protein (21 kDa, Protein from Tetrahymena thermophila SB210)
- Rieske iron-sulfur protein, ubiquinol-cytochrome c reductase iron-sulfur subunit (30 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf67 (54 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Thioredoxin (19 kDa, Protein from Tetrahymena thermophila SB210)
- Copper (ii) ion (63 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- O-[(r)-{[(2r)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-l-serine (792 Da, Ligand)
- Ndutt17 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Sdhtt11 (5 kDa, Protein from Tetrahymena thermophila SB210)
- Surf1-like protein (47 kDa, Protein from Tetrahymena thermophila SB210)
- Yflt domain-containing protein (19 kDa, Protein from Tetrahymena thermophila SB210)
- Ndua13 (21 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nmra domain-containing protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf57 (12 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (41 kDa, Protein from Tetrahymena thermophila SB210)
- Protein phosphatase 2c, putative (53 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (29 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome c oxidase subunit 1 (80 kDa, Protein from Tetrahymena thermophila SB210)
- Magnesium ion (24 Da, Ligand)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (20 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila SB210)
- Chch domain-containing protein (13 kDa, Protein from Tetrahymena thermophila SB210)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 1, chain, putative (28 kDa, Protein from Tetrahymena thermophila SB210)
- Sulphotransf domain-containing protein (39 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub6 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Apocytochrome b (50 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 9 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Lysozyme (12 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub8 (24 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (25 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf62 (30 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila SB210)
- Duf4885 domain-containing protein (12 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (18 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome c oxidase subunit vb protein (75 kDa, Protein from Tetrahymena thermophila SB210)
- Abc transporter (10 kDa, Protein from Tetrahymena thermophila SB210)
- Ubiquinone-10 (863 Da, Ligand)
- Decapping nuclease (10 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome c oxidase subunit 2 (72 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Complex i-mnll (12 kDa, Protein from Tetrahymena thermophila SB210)
- Ubiquinol-cytochrome c reductase hinge protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (22 kDa, Protein from Tetrahymena thermophila SB210)
- Zinc-finger protein (15 kDa, Protein from Tetrahymena thermophila SB210)
Cryo-EM structure of Tetrahymena thermophila respiratory Megacomplex MC (IV2+I+III2+II)2
Release date: June 14, 2023
Resolution: 4.18 Å
EM Method: Single-particle
Fitted PDBs: 8gzu
Q-score: 0.253
Resolution: 4.18 Å
EM Method: Single-particle
Fitted PDBs: 8gzu
Q-score: 0.253
Han F, Hu Y, Wu M, He Z, Tian H, Zhou L
Nat Commun (2023) 14 pp. 2542-2542 [ DOI: doi:10.1038/s41467-023-38158-5 Pubmed: 37248254 ]
Sample:
- M16 family peptidase, putative (53 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (28 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (41 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf75 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Structural protein (27 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 7 (51 kDa, Protein from Tetrahymena thermophila SB210)
- Cx9c domain-containing protein (28 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (7 kDa, Protein from Tetrahymena thermophila SB210)
- Sdhtt11 (5 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub10 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Cox assembly mitochondrial protein (17 kDa, Protein from Tetrahymena thermophila SB210)
- Phage protein (14 kDa, Protein from Tetrahymena thermophila SB210)
- 2-oxoglutarate/malate carrier protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome b-c1 complex subunit 8 (7 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (28 kDa, Protein from Tetrahymena thermophila SB210)
- Zf-tim10_ddp domain-containing protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt17 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub2 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (7 kDa, Protein from Tetrahymena thermophila SB210)
- Chch domain-containing protein (13 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf62 (30 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (52 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt3 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (23 kDa, Protein from Tetrahymena thermophila SB210)
- Atp synthase subunit e, mitochondrial (11 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 10 (18 kDa, Protein from Tetrahymena thermophila SB210)
- Uqcrtt2 (4 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 24 kda subunit (31 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase complex i, 21 kda subunit (17 kDa, Protein from Tetrahymena thermophila SB210)
- Transposase (8 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila SB210)
- Heme-a (852 Da, Ligand)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh dehydrogenase subunit 1 (7 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (21 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf70 (10 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Duf4885 domain-containing protein (12 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 75 kda subunit (80 kDa, Protein from Tetrahymena thermophila SB210)
- Annexin (8 kDa, Protein from Tetrahymena thermophila SB210)
- Trab family protein (45 kDa, Protein from Tetrahymena thermophila SB210)
- Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c (26 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome c oxidase subunit 1 (80 kDa, Protein from Tetrahymena thermophila SB210)
- Ubiquinone-10 (863 Da, Ligand)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila SB210)
- Rieske iron-sulfur protein, ubiquinol-cytochrome c reductase iron-sulfur subunit (30 kDa, Protein from Tetrahymena thermophila SB210)
- Complex iii subunit vii (19 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Apocytochrome b (50 kDa, Protein from Tetrahymena thermophila SB210)
- Iron-binding zinc finger cdgsh type protein (21 kDa, Protein from Tetrahymena thermophila SB210)
- 2 iron, 2 sulfur cluster-binding protein (19 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (11 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (18 kDa, Protein from Tetrahymena thermophila SB210)
- Abc transporter (10 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt22 (17 kDa, Protein from Tetrahymena thermophila SB210)
- Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (70 kDa, Protein from Tetrahymena thermophila SB210)
- Heme c (618 Da, Ligand)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila SB210)
- Sulphotransf domain-containing protein (39 kDa, Protein from Tetrahymena thermophila SB210)
- Gamma-carbonic anhydrase (25 kDa, Protein from Tetrahymena thermophila SB210)
- Lipid-a-disaccharide synthase (59 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub8 (24 kDa, Protein from Tetrahymena thermophila SB210)
- Yflt domain-containing protein (19 kDa, Protein from Tetrahymena thermophila SB210)
- Ubiquinol-cytochrome c reductase hinge protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8, mitochondrial (37 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl carrier protein (16 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf67 (54 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf65 (43 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (18 kDa, Protein from Tetrahymena thermophila SB210)
- Flavin mononucleotide (456 Da, Ligand)
- Ph domain-containing protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Chromosome condensation regulator rcc1 repeat protein (50 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (13 kDa, Protein from Tetrahymena thermophila SB210)
- Diphthamide synthesis protein (22 kDa, Protein from Tetrahymena thermophila SB210)
- Protein phosphatase 2c, putative (53 kDa, Protein from Tetrahymena thermophila SB210)
- Sdhd (5 kDa, Protein from Tetrahymena thermophila SB210)
- Surf1-like protein (35 kDa, Protein from Tetrahymena thermophila SB210)
- Rnase iii domain-containing protein (35 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (20 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 9 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Unknown peptide (7 kDa, Protein from Tetrahymena thermophila SB210)
- Complex i-mnll (12 kDa, Protein from Tetrahymena thermophila SB210)
- Lysozyme (12 kDa, Protein from Tetrahymena thermophila SB210)
- Fe3-s4 cluster (295 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (22 kDa, Protein from Tetrahymena thermophila SB210)
- Decapping nuclease (10 kDa, Protein from Tetrahymena thermophila SB210)
- Tim10/ddp family zinc finger protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (29 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt10 (28 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf58 (13 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt16 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (57 kDa, Protein from Tetrahymena thermophila SB210)
- Mobilization protein (23 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (14 kDa, Protein from Tetrahymena thermophila SB210)
- Tetrahymena thermophila respiratory mega-complex mc (iv2+i+iii2+ii)2 (10 MDa, Complex from Tetrahymena thermophila SB210)
- Nduph2 (22 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (12 kDa, Protein from Tetrahymena thermophila SB210)
- Succinate dehydrogenase (quinone) (36 kDa, Protein from Tetrahymena thermophila SB210)
- Gram domain protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt9 (29 kDa, Protein from Tetrahymena thermophila SB210)
- Flavin-adenine dinucleotide (785 Da, Ligand)
- Transmembrane protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Magnesium ion (24 Da, Ligand)
- Ymf57 (12 kDa, Protein from Tetrahymena thermophila SB210)
- Cullin domain-containing protein (8 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase, putative (20 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 4 (58 kDa, Protein from Tetrahymena thermophila SB210)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Transposase (11 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome c oxidase subunit 2 (72 kDa, Protein from Tetrahymena thermophila SB210)
- Copper (ii) ion (63 Da, Ligand)
- Dnaj domain protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (14 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 2 (20 kDa, Protein from Tetrahymena thermophila SB210)
- Nad-dependent epimerase/dehydratase family protein (41 kDa, Protein from Tetrahymena thermophila SB210)
- Acyl-coa synthetase (amp-forming)/amp-acid ligase ii (36 kDa, Protein from Tetrahymena thermophila SB210)
- Ndua13 (21 kDa, Protein from Tetrahymena thermophila SB210)
- Zinc-finger protein (15 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub4 (17 kDa, Protein from Tetrahymena thermophila SB210)
- Nmra domain-containing protein (36 kDa, Protein from Tetrahymena thermophila SB210)
- 39s ribosomal protein l9, mitochondrial (27 kDa, Protein from Tetrahymena thermophila SB210)
- Peptidase m16 inactive domain protein (58 kDa, Protein from Tetrahymena thermophila SB210)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Zf-tim10_ddp domain-containing protein (10 kDa, Protein from Tetrahymena thermophila SB210)
- Transcription factor apfi protein, putative (39 kDa, Protein from Tetrahymena thermophila SB210)
- Ribosomal protein l51/s25/ci-b8 domain protein (12 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Coxtt28 (11 kDa, Protein from Tetrahymena thermophila SB210)
- 37s ribosomal protein s25, mitochondrial (33 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome c oxidase subunit vb protein (75 kDa, Protein from Tetrahymena thermophila SB210)
- Sdhtt3 (23 kDa, Protein from Tetrahymena thermophila SB210)
- Ymf68 (72 kDa, Protein from Tetrahymena thermophila SB210)
- Zinc ion (65 Da, Ligand)
- Etc complex i subunit motif protein (24 kDa, Protein from Tetrahymena thermophila SB210)
- Ndub6 (15 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase chain 1 (32 kDa, Protein from Tetrahymena thermophila SB210)
- Unknown peptide (1 kDa, Protein from Tetrahymena thermophila SB210)
- Oxoglutarate/malate translocator protein, putative (40 kDa, Protein from Tetrahymena thermophila SB210)
- Cytochrome protein c1 (37 kDa, Protein from Tetrahymena thermophila SB210)
- Ndutt15 (27 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein, putative (35 kDa, Protein from Tetrahymena thermophila SB210)
- Thioredoxin (19 kDa, Protein from Tetrahymena thermophila SB210)
- Carrier protein (37 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh dehydrogenase subunit 5 (88 kDa, Protein from Tetrahymena thermophila SB210)
- Ctf/nf-i domain-containing protein (116 kDa, Protein from Tetrahymena thermophila SB210)
- Surf1-like protein (47 kDa, Protein from Tetrahymena thermophila SB210)
- Nadh-ubiquinone oxidoreductase 1, chain, putative (28 kDa, Protein from Tetrahymena thermophila SB210)
- Transmembrane protein (20 kDa, Protein from Tetrahymena thermophila SB210)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (inhibited by DDM)
Release date: Nov. 30, 2022
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 7zm7
Q-score: 0.598
Resolution: 2.77 Å
EM Method: Single-particle
Fitted PDBs: 7zm7
Q-score: 0.598
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ Pubmed: 36427319 DOI: doi:10.1126/sciadv.adc9952 ]
Sample:
- Flavin mononucleotide (456 Da, Ligand)
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (29 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase-like protein (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (82 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Nadh dehydrogenase (ubiquinone)-like protein (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like domain-containing protein (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh-ubiquinone oxidoreductase b14 subunit-like protein (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (18 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 49 kda subunit-like protein (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 30.4 kda subunit-like protein (33 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in ddm (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufv2 of nadh-ubiquinone oxidoreductase (complex i) (35 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (43 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
Release date: Nov. 30, 2022
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7zm8
Q-score: 0.604
Resolution: 2.76 Å
EM Method: Single-particle
Fitted PDBs: 7zm8
Q-score: 0.604
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ Pubmed: 36427319 DOI: doi:10.1126/sciadv.adc9952 ]
Sample:
- Cardiolipin (1 kDa, Ligand)
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (89 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in ddm (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Dodecyl-beta-d-maltoside (510 Da, Ligand)
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2)
Release date: Nov. 30, 2022
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 7zmb
Q-score: 0.598
Resolution: 2.75 Å
EM Method: Single-particle
Fitted PDBs: 7zmb
Q-score: 0.598
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ Pubmed: 36427319 DOI: doi:10.1126/sciadv.adc9952 ]
Sample:
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase-like protein (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 49 kda subunit-like protein (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in lmng (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (82 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase b14 subunit-like protein (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (18 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 30.4 kda subunit-like protein (33 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (29 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like domain-containing protein (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (43 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit ndufv2 of nadh-ubiquinone oxidoreductase (complex i) (35 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 2) - membrane arm
Release date: Nov. 30, 2022
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7zme
Q-score: 0.596
Resolution: 2.83 Å
EM Method: Single-particle
Fitted PDBs: 7zme
Q-score: 0.596
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ Pubmed: 36427319 DOI: doi:10.1126/sciadv.adc9952 ]
Sample:
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (89 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in lmng (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1)
Release date: Nov. 30, 2022
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 7zmg
Q-score: 0.667
Resolution: 2.44 Å
EM Method: Single-particle
Fitted PDBs: 7zmg
Q-score: 0.667
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ Pubmed: 36427319 DOI: doi:10.1126/sciadv.adc9952 ]
Sample:
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase-like protein (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 49 kda subunit-like protein (55 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in lmng (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (82 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Zinc ion (65 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (23 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase b14 subunit-like protein (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (18 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase 30.4 kda subunit-like protein (33 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (29 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like domain-containing protein (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (43 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Iron/sulfur cluster (351 Da, Ligand)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Subunit ndufv2 of nadh-ubiquinone oxidoreductase (complex i) (35 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Flavin mononucleotide (456 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Oxidoreductase-like protein (25 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
CryoEM structure of mitochondrial complex I from Chaetomium thermophilum (state 1) - membrane arm
Release date: Nov. 30, 2022
Resolution: 2.47 Å
EM Method: Single-particle
Fitted PDBs: 7zmh
Q-score: 0.672
Resolution: 2.47 Å
EM Method: Single-particle
Fitted PDBs: 7zmh
Q-score: 0.672
Laube E, Meier-Credo J, Langer JD, Kuhlbrandt W
Sci Adv (2022) 8 pp. eadc9952-eadc9952 [ Pubmed: 36427319 DOI: doi:10.1126/sciadv.adc9952 ]
Sample:
- Subunit ndufc2 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Acyl carrier protein (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufs5 of nadh-ubiquinone oxidoreductase (complex i) (87 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Lauryl maltose neopentyl glycol (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (60 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 3 (16 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase (ubiquinone)-like protein (89 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (24 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufa1 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase-like protein (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Subunit ndufa3 of nadh-ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Mitochondrial nadh:ubiquinone oxidoreductase in lmng (970 kDa, Complex from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb10 of nadh-ubiquinone oxidoreductase (complex i) (12 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 (14 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb2 of nadh-ubiquinone oxidoreductase (complex i) (5 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb3 of nadh-ubiquinone oxidoreductase (complex i) (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh-ubiquinone oxidoreductase chain 1 (41 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Water (18 Da, Ligand)
- Nadh-ubiquinone oxidoreductase (21 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb4 of nadh-ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb5 of nadh-ubiquinone oxidoreductase (complex i) (20 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Complex i-b22 (11 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (75 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Nadh dehydrogenase subunit 2 (64 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Subunit ndufb6 of nadh-ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
- Complex i-esss (15 kDa, Protein from Chaetomium thermophilum var. thermophilum DSM 1495)
Release date: Nov. 23, 2022
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7zkp
Q-score: 0.415
Resolution: 3.2 Å
EM Method: Single-particle
Fitted PDBs: 7zkp
Q-score: 0.415
Schiller J, Laube E, Wittig I, Kuhlbrandt W, Vonck J, Zickermann V
Sci Adv (2022) 8 pp. eadd3855-eadd3855 [ DOI: doi:10.1126/sciadv.add3855 Pubmed: 36383672 ]
Sample:
- Subunit nupm of nadh:ubiquinone oxidoreductase (complex i) (19 kDa, Protein from Yarrowia lipolytica)
- Assembly factor cia84 (97 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Yarrowia lipolytica)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 1 (38 kDa, Protein from Yarrowia lipolytica)
- Subunit nimm of nadh:ubiquinone oxidoreductase (complex i) (9 kDa, Protein from Yarrowia lipolytica)
- Diundecyl phosphatidyl choline (622 Da, Ligand)
- Cia30 domain-containing protein (32 kDa, Protein from Yarrowia lipolytica)
- Subunit nb6m of nadh:ubiquinone oxidoreductase (complex i) (14 kDa, Protein from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase complex i, 21 kda subunit-domain-containing protein (18 kDa, Protein from Yarrowia lipolytica)
- Subunit nebm of nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Phosphatidylinositol (887 Da, Ligand)
- Late assembly intermediate of the proximal proton pumping module of complex i with assembly factors ndufaf1 and cia84 (Complex from Yarrowia lipolytica)
- Nadh-ubiquinone oxidoreductase chain 6 (20 kDa, Protein from Yarrowia lipolytica)
- 1-palmitoyl-2-linoleoyl-sn-glycero-3-phosphocholine (758 Da, Ligand)
- Subunit ni9m of protein nadh:ubiquinone oxidoreductase (complex i) (8 kDa, Protein from Yarrowia lipolytica)
- Subunit nipm of nadh:ubiquinone oxidoreductase (complex i) (10 kDa, Protein from Yarrowia lipolytica)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4l (9 kDa, Protein from Yarrowia lipolytica)
- Nadh dehydrogenase subunit 2 (53 kDa, Protein from Yarrowia lipolytica)
Cryo-EM structure of respiratory super-complex CI+III2 from Tetrahymena thermophila
Release date: April 6, 2022
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7tgh
Q-score: 0.605
Resolution: 2.6 Å
EM Method: Single-particle
Fitted PDBs: 7tgh
Q-score: 0.605
Zhou L, Maldonado M, Padavannil A, Guo F, Letts JA
Science (2022) 376 pp. 831-839 [ Pubmed: 35357889 DOI: doi:10.1126/science.abn7747 ]
Sample:
- Apocytochrome b (50 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (7 kDa, Protein from Tetrahymena thermophila)
- Ymf65 (43 kDa, Protein from Tetrahymena thermophila)
- Zinc-finger protein (15 kDa, Protein from Tetrahymena thermophila)
- Ndutt9 (15 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (29 kDa, Protein from Tetrahymena thermophila)
- Lipid-a-disaccharide synthase (59 kDa, Protein from Tetrahymena thermophila)
- Unk1 (2 kDa, Protein from Tetrahymena thermophila)
- Ymf62 (30 kDa, Protein from Tetrahymena thermophila)
- Ndub10 (22 kDa, Protein from Tetrahymena thermophila)
- Ndub4 (12 kDa, Protein from Tetrahymena thermophila)
- Gamma-carbonic anhydrase (28 kDa, Protein from Tetrahymena thermophila)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Etc complex i subunit motif protein (24 kDa, Protein from Tetrahymena thermophila)
- Uqcrb (39 kDa, Protein from Tetrahymena thermophila)
- Ndub7 (13 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (9 kDa, Protein from Tetrahymena thermophila)
- Peptidase m16 inactive domain protein (58 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (21 kDa, Protein from Tetrahymena thermophila)
- Acyl-coa synthetase (amp-forming)/amp-acid ligase ii (36 kDa, Protein from Tetrahymena thermophila)
- Adenosine-5'-diphosphate (427 Da, Ligand)
- Nadh-ubiquinone oxidoreductase 24 kda subunit (31 kDa, Protein from Tetrahymena thermophila)
- Heme c (618 Da, Ligand)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Transmembrane protein, putative (24 kDa, Protein from Tetrahymena thermophila)
- Thioredoxin (19 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase complex i, 21 kda subunit (17 kDa, Protein from Tetrahymena thermophila)
- Unk2 (1 kDa, Protein from Tetrahymena thermophila)
- S-[2-({n-[(2s)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] tetradecanethioate (568 Da, Ligand)
- Transmembrane protein, putative (23 kDa, Protein from Tetrahymena thermophila)
- Unk5 (13 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 1 (7 kDa, Protein from Tetrahymena thermophila)
- Rieske iron-sulfur protein, ubiquinol-cytochrome c reductase iron-sulfur subunit (30 kDa, Protein from Tetrahymena thermophila)
- Ndutt3 (35 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (22 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (52 kDa, Protein from Tetrahymena thermophila)
- Nduph2 (22 kDa, Protein from Tetrahymena thermophila)
- Ndutt10 (12 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase chain 3 (14 kDa, Protein from Tetrahymena thermophila)
- Cardiolipin (1 kDa, Ligand)
- Ndutt6 (17 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 10 (18 kDa, Protein from Tetrahymena thermophila)
- Dnaj domain protein (36 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (26 kDa, Protein from Tetrahymena thermophila)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Mitochondrial super-complex i+iii2 of tetrahymena thermophila (2 MDa, Complex from Tetrahymena thermophila)
- Transmembrane protein, putative (15 kDa, Protein from Tetrahymena thermophila)
- Iron/sulfur cluster (351 Da, Ligand)
- Gram domain protein (10 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (14 kDa, Protein from Tetrahymena thermophila)
- Ndua7 (33 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase chain 1 (32 kDa, Protein from Tetrahymena thermophila)
- Ndutt12 (11 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase 1, chain, putative (28 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase, putative (20 kDa, Protein from Tetrahymena thermophila)
- Zinc ion (65 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 4 (58 kDa, Protein from Tetrahymena thermophila)
- Ndub8 (24 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 2 (20 kDa, Protein from Tetrahymena thermophila)
- Ndub6 (15 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 7 (51 kDa, Protein from Tetrahymena thermophila)
- Gamma-carbonic anhydrase (25 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (13 kDa, Protein from Tetrahymena thermophila)
- Ndutt4 (24 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (8 kDa, Protein from Tetrahymena thermophila)
- Flavin mononucleotide (456 Da, Ligand)
- Nduc2 (12 kDa, Protein from Tetrahymena thermophila)
- Ymf57 (12 kDa, Protein from Tetrahymena thermophila)
- Ndua8 (28 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 5 (88 kDa, Protein from Tetrahymena thermophila)
- Ndua13 (21 kDa, Protein from Tetrahymena thermophila)
- Cytochrome protein c1 (37 kDa, Protein from Tetrahymena thermophila)
- Unk3 (1 kDa, Protein from Tetrahymena thermophila)
- Ndutt8 (15 kDa, Protein from Tetrahymena thermophila)
- Ndub9 (22 kDa, Protein from Tetrahymena thermophila)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Nad-dependent epimerase/dehydratase family protein (41 kDa, Protein from Tetrahymena thermophila)
- Transcription factor apfi protein, putative (39 kDa, Protein from Tetrahymena thermophila)
- 2 iron, 2 sulfur cluster-binding protein (19 kDa, Protein from Tetrahymena thermophila)
- Unk4 (17 kDa, Protein from Tetrahymena thermophila)
- Ndua1 (11 kDa, Protein from Tetrahymena thermophila)
- Ubiquinol-cytochrome c reductase hinge protein (10 kDa, Protein from Tetrahymena thermophila)
- Nadh dehydrogenase subunit 9 (23 kDa, Protein from Tetrahymena thermophila)
- M16 family peptidase, putative (53 kDa, Protein from Tetrahymena thermophila)
- Ndub2 (14 kDa, Protein from Tetrahymena thermophila)
- Ubiquinone-10 (863 Da, Ligand)
- Ymf58 (13 kDa, Protein from Tetrahymena thermophila)
- Acyl carrier protein (15 kDa, Protein from Tetrahymena thermophila)
- Ribosomal protein l51/s25/ci-b8 domain protein (12 kDa, Protein from Tetrahymena thermophila)
- Acyl carrier protein (16 kDa, Protein from Tetrahymena thermophila)
- Nadh-ubiquinone oxidoreductase 75 kda subunit (80 kDa, Protein from Tetrahymena thermophila)
- Transmembrane protein, putative (16 kDa, Protein from Tetrahymena thermophila)