In-situ structure of typeA supercomplex with lipids in respiratory chain (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform x1 (13 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Sodium ion (22 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Dinuclear copper ion (127 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (52 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- (1s)-2-{[{[(2r)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl stearate (751 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (48 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit ab1 (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 (19 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 6a2 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a13 (16 kDa, Protein from Sus scrofa)
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- N-acetylalanine (131 Da, Ligand)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 7b (9 kDa, Protein from Sus scrofa)
- N-acetylmethionine (191 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [sus scrofa] (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome c oxidase subunit ndufa4 (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sus scrofa)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5e,8e,11e,14e)-icosa-5,8,11,14-tetraenoate (768 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (28 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 8 (7 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Sus scrofa)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Sus scrofa)
In-situ structure of typeB supercomplex in respiratory chain (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform x1 (13 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Sodium ion (22 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Dinuclear copper ion (127 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein 53 complext iii (6 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (48 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit ab1 (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (54 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 (19 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 6a2 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a13 (16 kDa, Protein from Sus scrofa)
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- N-acetylalanine (131 Da, Ligand)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 7b (9 kDa, Protein from Sus scrofa)
- N-acetylmethionine (191 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [sus scrofa] (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome c oxidase subunit ndufa4 (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sus scrofa)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5e,8e,11e,14e)-icosa-5,8,11,14-tetraenoate (768 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (28 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 8 (7 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Sus scrofa)
- Cholic acid (408 Da, Ligand)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Sus scrofa)
In-situ structure of typeO supercomplex in respiratory chain (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform x1 (13 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Sodium ion (22 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Dinuclear copper ion (127 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein 53 complext iii (7 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (48 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit ab1 (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (54 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 (19 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 6a2 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a13 (16 kDa, Protein from Sus scrofa)
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- N-acetylalanine (131 Da, Ligand)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 7b (9 kDa, Protein from Sus scrofa)
- N-acetylmethionine (191 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [sus scrofa] (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome c oxidase subunit ndufa4 (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sus scrofa)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5e,8e,11e,14e)-icosa-5,8,11,14-tetraenoate (768 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (28 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 8 (7 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Sus scrofa)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Sus scrofa)
In-situ structure of typeX supercomplex in respiratory chain (composite)
Zheng W, Chai P, Zhu J, Zhang K
Nature (2024) [ Pubmed: 38811722 DOI: doi:10.1038/s41586-024-07488-9 ]
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (21 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform x1 (13 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 5b, mitochondrial (13 kDa, Protein from Sus scrofa)
- Cardiolipin (1 kDa, Ligand)
- Nadh-ubiquinone oxidoreductase chain 2 (39 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 (16 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4 (51 kDa, Protein from Sus scrofa)
- Sodium ion (22 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 (14 kDa, Protein from Sus scrofa)
- Dinuclear copper ion (127 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (50 kDa, Protein from Sus scrofa)
- In-situ cryo-em structure of respiratory supercomplex by directly imaging mitochondria (Complex from Sus scrofaSus scrofa)
- Cytochrome c oxidase subunit 7c, mitochondrial (7 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 8 (9 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase 75 kda subunit, mitochondrial (79 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 1 (57 kDa, Protein from Sus scrofa)
- Protoporphyrin ix containing fe (616 Da, Ligand)
- Cytochrome b-c1 complex subunit 7 (13 kDa, Protein from Sus scrofa)
- Iron/sulfur cluster (351 Da, Ligand)
- Cytochrome b-c1 complex subunit rieske, mitochondrial (29 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 (15 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6b1 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (48 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- Phosphate ion (94 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit ab1 (17 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 2 (26 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 4l (10 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 2, mitochondrial (48 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 6c (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (54 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (21 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 4 (19 kDa, Protein from Sus scrofa)
- Cytochrome b (42 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 7a1, mitochondrial (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 (9 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 5 (68 kDa, Protein from Sus scrofa)
- 1,2-diacyl-sn-glycero-3-phosphocholine (790 Da, Ligand)
- Zinc ion (65 Da, Ligand)
- Nadh:ubiquinone oxidoreductase subunit b2 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 5 (12 kDa, Protein from Sus scrofa)
- Copper (ii) ion (63 Da, Ligand)
- Cytochrome c oxidase subunit 6a2 (10 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (8 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a13 (16 kDa, Protein from Sus scrofa)
- Cytochrome c1 (35 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (27 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (21 kDa, Protein from Sus scrofa)
- N-acetylalanine (131 Da, Ligand)
- Cytochrome c oxidase subunit 5a, mitochondrial (16 kDa, Protein from Sus scrofa)
- 1,2-distearoyl-sn-glycerophosphoethanolamine (748 Da, Ligand)
- Cytochrome c oxidase subunit 7b (9 kDa, Protein from Sus scrofa)
- N-acetylmethionine (191 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 (11 kDa, Protein from Sus scrofa)
- Heme-a (852 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 (20 kDa, Protein from Sus scrofa)
- Cytochrome b-c1 complex subunit 6, mitochondrial (10 kDa, Protein from Sus scrofa)
- Guanosine-5'-triphosphate (523 Da, Ligand)
- Cytochrome b-c1 complex subunit 1, mitochondrial (52 kDa, Protein from Sus scrofa)
- Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate (745 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c1, mitochondrial (8 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (30 kDa, Protein from Sus scrofa)
- Nadh:ubiquinone oxidoreductase subunit a9 (42 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [sus scrofa] (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (13 kDa, Protein from Sus scrofa)
- Flavin mononucleotide (456 Da, Ligand)
- Cytochrome c oxidase subunit ndufa4 (9 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (19 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (15 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 (20 kDa, Protein from Sus scrofa)
- ~{s}-[2-[3-[[(2~{r})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{s})-3-oxidanyltetradecanethioate (584 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 (12 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (11 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (17 kDa, Protein from Sus scrofa)
- Nadh-ubiquinone oxidoreductase chain 3 (13 kDa, Protein from Sus scrofa)
- Ubiquinol-cytochrome c reductase complex 7.2 kda protein (7 kDa, Protein from Sus scrofa)
- (1s)-2-{[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-1-[(stearoyloxy)methyl]ethyl (5e,8e,11e,14e)-icosa-5,8,11,14-tetraenoate (768 Da, Ligand)
- (1r)-2-{[{[(2s)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(palmitoyloxy)methyl]ethyl (11e)-octadec-11-enoate (749 Da, Ligand)
- Nadh dehydrogenase [ubiquinone] 1 subunit c2 (14 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (28 kDa, Protein from Sus scrofa)
- Heme c (618 Da, Ligand)
- Myristic acid (228 Da, Ligand)
- Nadh-ubiquinone oxidoreductase chain 6 (19 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 8 (7 kDa, Protein from Sus scrofa)
- Cytochrome c oxidase subunit 3 (29 kDa, Protein from Sus scrofa)
- (7r,17e,20e)-4-hydroxy-n,n,n-trimethyl-9-oxo-7-[(palmitoyloxy)methyl]-3,5,8-trioxa-4-phosphahexacosa-17,20-dien-1-aminium 4-oxide (759 Da, Ligand)
- Cytochrome b-c1 complex subunit 10 (6 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (40 kDa, Protein from Sus scrofa)
- Nadh dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (17 kDa, Protein from Sus scrofa)
55S mammalian mitochondrial ribosome with mtRF1 and P-site tRNA
Resolution: 3.6 Å
EM Method: Single-particle
Fitted PDBs: 8oin
Q-score: 0.384
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A, Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R, Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban N
Science (2023) 380 pp. 531-536 [ DOI: doi:10.1126/science.adf9890 Pubmed: 37141370 ]
- Zinc ion (65 Da, Ligand)
- Ul16m (28 kDa, Protein from Sus scrofa)
- N-formylmethionine (177 Da, Ligand)
- Small ribosomal subunit protein ms29 (46 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l13, mitochondrial (22 kDa, Protein from Sus scrofa)
- 12s rrna (308 kDa, RNA from Sus scrofa)
- Us9m (45 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l40 (19 kDa, Protein from Sus scrofa)
- Ml54 (15 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- 28s ribosomal protein s15, mitochondrial (29 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Sus scrofa)
- 28s ribosomal protein s31, mitochondrial (43 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Sus scrofa)
- Spermidine (145 Da, Ligand)
- 28s ribosomal protein s16, mitochondrial (15 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s25 (19 kDa, Protein from Sus scrofa)
- Ul24m (24 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l57 (12 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s26 (23 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l2 (33 kDa, Protein from Sus scrofa)
- Mrpl34 (18 kDa, Protein from Sus scrofa)
- Ribosomal protein (10 kDa, Protein from Sus scrofa)
- Ict1 (43 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l39 (38 kDa, Protein from Sus scrofa)
- Ml62 (ict1) (23 kDa, Protein from Sus scrofa)
- Small ribosomal subunit protein ms38 (22 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l52, mitochondrial (17 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s24 (18 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s2 (31 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Mitochondrial ribosomal protein s34 (55 kDa, Protein from Sus scrofa)
- Guanosine-5'-diphosphate (443 Da, Ligand)
- 28s ribosomal protein s18b, mitochondrial (29 kDa, Protein from Sus scrofa)
- E-site trna (894 Da, RNA from Sus scrofa)
- Cp phe-trna (23 kDa, RNA from Sus scrofa)
- Ml64 (25 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l1, mitochondrial (34 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l11 (20 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l53 (12 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l10 (29 kDa, Protein from Sus scrofa)
- Spermine (202 Da, Ligand)
- Ms23 (21 kDa, Protein from Sus scrofa)
- Large ribosomal subunit protein ml51 (15 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l32 (23 kDa, Protein from Sus scrofa)
- Large ribosomal subunit protein bl34m (10 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s22 (43 kDa, Protein from Sus scrofa)
- Water (18 Da, Ligand)
- 55s mammalian mitochondrial ribosome with mtrf1 and p-site trna (2 MDa, Complex from Sus scrofa)
- Large ribosomal subunit protein ul30m (18 kDa, Protein from Sus scrofa)
- Ml42 (16 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l48, mitochondrial (29 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l14 (34 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l50 (22 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s27 (45 kDa, Protein from Sus scrofa)
- 28s ribosomal protein s35, mitochondrial isoform 1 (41 kDa, Protein from Sus scrofa)
- Large ribosomal subunit protein bl33m (7 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s10 (23 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l55 (15 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l27, mitochondrial (15 kDa, Protein from Sus scrofa)
- 28s ribosomal protein s17, mitochondrial (14 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l18 (21 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l47 (29 kDa, Protein from Sus scrofa)
- Ml44 (37 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l21 (23 kDa, Protein from Sus scrofa)
- 39s ribosomal protein s30, mitochondrial (49 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Sus scrofa)
- Large ribosomal subunit protein ml43 (17 kDa, Protein from Sus scrofa)
- 28s ribosomal protein s21, mitochondrial (10 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s33 (16 kDa, Protein from Sus scrofa)
- 28s ribosomal protein s5, mitochondrial isoform x2 (48 kDa, Protein from Sus scrofa)
- Mitoribosomal protein ms28, mrps28 (21 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l46 (32 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s7 (28 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l20 (17 kDa, Protein from Sus scrofa)
- Bl17m (19 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l45 (35 kDa, Protein from Sus scrofa)
- P-site met-trna(fmet) (22 kDa, RNA from Homo sapiens)
- Mitochondrial ribosomal protein l9 (30 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l38 (44 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l4 (33 kDa, Protein from Sus scrofa)
- Mrna (2 kDa, RNA from Homo sapiens)
- Peptide chain release factor 1, mitochondrial (55 kDa, Protein from Homo sapiens)
- Mitochondrial ribosomal protein l12 (21 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l37 (47 kDa, Protein from Sus scrofa)
- Ms39 (78 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s18c (16 kDa, Protein from Sus scrofa)
- Mitoribosomal protein bs6m, mrps6 (14 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s14 (15 kDa, Protein from Sus scrofa)
- Adenosine-5'-triphosphate (507 Da, Ligand)
- Large ribosomal subunit protein ul22m (24 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- 16s rrna (504 kDa, RNA from Sus scrofa)
- 39s ribosomal protein l19, mitochondrial (34 kDa, Protein from Sus scrofa)
- Phenylalanine (165 Da, Ligand)
- Coiled-coil-helix-coiled-coil-helix domain containing 1 (13 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s11 (20 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l28 (30 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s18a (22 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s12 (15 kDa, Protein from Sus scrofa)
39S mammalian mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA
Resolution: 3.5 Å
EM Method: Single-particle
Fitted PDBs: 8oiq
Q-score: 0.44
Saurer M, Leibundgut M, Nadimpalli HP, Scaiola A, Schonhut T, Lee RG, Siira SJ, Rackham O, Dreos R, Lenarcic T, Kummer E, Gatfield D, Filipovska A, Ban N
Science (2023) 380 pp. 531-536 [ DOI: doi:10.1126/science.adf9890 Pubmed: 37141370 ]
- 39s ribosomal protein l49, mitochondrial (18 kDa, Protein from Sus scrofa)
- Ict1 (43 kDa, Protein from Sus scrofa)
- Zinc ion (65 Da, Ligand)
- Large ribosomal subunit protein ul30m (18 kDa, Protein from Sus scrofa)
- Ml42 (16 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l48, mitochondrial (29 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l14 (34 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l50 (22 kDa, Protein from Sus scrofa)
- Bl17m (19 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l39 (38 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l45 (35 kDa, Protein from Sus scrofa)
- Ml62 (ict1) (23 kDa, Protein from Sus scrofa)
- Ul16m (28 kDa, Protein from Sus scrofa)
- P-site met-trna(fmet) (22 kDa, RNA from Homo sapiens)
- N-formylmethionine (177 Da, Ligand)
- Mitochondrial ribosomal protein l9 (30 kDa, Protein from Sus scrofa)
- Large ribosomal subunit protein bl33m (7 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l52, mitochondrial (17 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l38 (44 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l13, mitochondrial (22 kDa, Protein from Sus scrofa)
- Potassium ion (39 Da, Ligand)
- Mitochondrial ribosomal protein l4 (33 kDa, Protein from Sus scrofa)
- Peptide chain release factor 1, mitochondrial (55 kDa, Protein from Homo sapiens)
- Mitochondrial ribosomal protein l12 (21 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l55 (15 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l37 (47 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l40 (19 kDa, Protein from Sus scrofa)
- Ml54 (15 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l27, mitochondrial (15 kDa, Protein from Sus scrofa)
- Fe2/s2 (inorganic) cluster (175 Da, Ligand)
- E-site trna (894 Da, RNA from Sus scrofa)
- Cp phe-trna (23 kDa, RNA from Sus scrofa)
- Mitochondrial ribosomal protein l18 (21 kDa, Protein from Sus scrofa)
- Large ribosomal subunit protein ul22m (24 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l47 (29 kDa, Protein from Sus scrofa)
- Ml64 (25 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l1, mitochondrial (34 kDa, Protein from Sus scrofa)
- Ml44 (37 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l15, mitochondrial (33 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l21 (23 kDa, Protein from Sus scrofa)
- Magnesium ion (24 Da, Ligand)
- 39s ribosomal protein l23, mitochondrial (17 kDa, Protein from Sus scrofa)
- 16s rrna (504 kDa, RNA from Sus scrofa)
- Mitochondrial ribosomal protein l11 (20 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l19, mitochondrial (34 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l53 (12 kDa, Protein from Sus scrofa)
- Phenylalanine (165 Da, Ligand)
- 39s ribosomal protein s30, mitochondrial (49 kDa, Protein from Sus scrofa)
- Ul24m (24 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l35, mitochondrial (21 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l10 (29 kDa, Protein from Sus scrofa)
- Large ribosomal subunit protein ml43 (17 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l28 (30 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l57 (12 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l32 (23 kDa, Protein from Sus scrofa)
- 39s mammalian mitochondrial ribosome with mtrf1 and p-site trnamet (1 MDa, Complex from Sus scrofa)
- Large ribosomal subunit protein bl34m (10 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l2 (33 kDa, Protein from Sus scrofa)
- 39s ribosomal protein l41, mitochondrial (15 kDa, Protein from Sus scrofa)
- Large ribosomal subunit protein ml51 (15 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein s18a (22 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l46 (32 kDa, Protein from Sus scrofa)
- Mitochondrial ribosomal protein l20 (17 kDa, Protein from Sus scrofa)
- Ribosomal protein (10 kDa, Protein from Sus scrofa)