Family C23

Family

Summary Holotypes Alignment Tree Genomes Literature Architecture

Summary for family C23

Family type peptidase	C23.001 - carlavirus peptidase (apple stem pitting virus), MEROPS Accession MER0002101 (peptidase unit: 1192-1288)
Content of family	Peptidase family C23 contains cysteine endopeptidases of single-stranded RNA viruses.
History	Identifier created: Perspect.Drug Discov.Des. 6:1-11 (1996)
Catalytic type	Cysteine
Active site residues	C1202 H1283
Active site	Cys1202 and His1283 are catalytic residues (Lawrence et al., 1995).
Activities and specificities	Like other, similar peptidases of plant viruses, the peptidases of family C23 cleave in cis but not in trans, and an AlaAsp cleavage site has been tentatively identified (Lawrence et al., 1995).
Molecular structure
Clan	unassigned
Basis of clan assignment	Active site residues for members of this family and family C1 occur in the same order in the sequence: C, H.

Distribution of family	Bacteria	-
	Archaea	-
	Protozoa	-
	Fungi	-
	Plants	-
	Animals	-
	Viruses	details

Biological functions	The peptidases of the family are necessary for the processing of the carlavirus polyproteins.
Statistics for family C23	Sequences:	44
	Identifiers:	1
	Identifiers with PDB entries:	0
Downloadable files	Sequence library (FastA format)
	Sequence alignment (FastA format)
	Phylogenetic tree (Newick format)

Other databases	INTERPRO	IPR008041
	PFAM	PF05379

Peptidases and Homologues	MEROPS ID	Structure
carlavirus peptidase	C23.001	-
Family C23 unassigned peptidases	unassigned	-