Incompletely Sequenced Peptidases
There are still a number of peptidases for which we have not got complete sequence information. Most of the incompletely sequenced peptidases cannot be allocated to families, and special identifiers are needed for these. Each such identifier starts with a letter for the catalytic type (Aspartic, Cysteine, Metallo, Serine, Threonine or Unknown) followed by 9 and then a letter indicating the type of peptidase activity (A, aminopeptidase; B, dipeptidase; C, di- or tri-peptidyl-peptidase; D, peptidyl-dipeptidase; E, carboxypeptidase; F, omega peptidase, or G, endopeptidase.
| ASPARTIC PEPTIDASES | ||
|---|---|---|
| aspartic peptidase, plasma | A9G.001 | - |
| acid peptidase (Cladosporium) | A9G.017 | - |
| acid peptidase (Paecilomyces) | A9G.018 | - |
| acrocylindropepsin | A9G.019 | EC 3.4.23.28 |
| pycnoporopepsin | A9G.010 | EC 3.4.23.30 |
| yapsin A | A9G.020 | EC 3.4.23.17 |
| CYSTEINE PEPTIDASES | ||
| bothropain | C9G.030 | - |
| cathepsin N | C9G.001 | - |
| cathepsin T | C9G.005 | EC 3.4.22.24 |
| cathepsin M (old) | C9G.009 | - |
| cysteine peptidase (Micrococcus sp. INIA 528) | C9G.022 | - |
| dipeptidyl-dipeptidase | C9C.001 | EC 3.4.14.6 |
| lysosomal dipeptidase II | C9B.001 | - |
| leucoegresin-generating peptidase | C9G.002 | - |
| mitochondrial cysteine peptidase | C9G.004 | - |
| nuclear cysteine peptidase | C9G.006 | - |
| PlyPy phage lysin | C104.002 | - |
| protease-B-17N-1 (Bacillus sp. 17N-1) | C9G.031 | - |
| METALLOPEPTIDASES | ||
| atrolysin F | M12.146 | EC 3.4.24.45 |
| alpha peptidase (Crotalus atrox) | M12.168 | - |
| ammodytase | M12.190 | - |
| acutolysin D | M12.317 | - |
| aminopeptidase X | M9A.009 | - |
| alanine carboxypeptidase | M9E.002 | EC 3.4.17.6 |
| acrolysin | M9G.003 | - |
| aharin | M9G.041 | - |
| atroxin | M9G.059 | - |
| BHRa hemorrhagin (Bitis arietans) | M12.137 | - |
| BaH1 peptidase (Bothrops asper) | M12.166 | - |
| bilitoxin 2 (Agkistrodon bilineatus) | M12.179 | - |
| BHRb haemorrhagin (Bitis arietans) | M12.306 | - |
| BJ-PI peptidase | M12.340 | - |
| clostridial aminopeptidase | M9A.005 | EC 3.4.11.13 |
| carboxypeptidase G3 | M9E.007 | - |
| cyclic peptidase (Lactocobacillus) | M9G.031 | - |
| dactylysin | M9G.026 | EC 3.4.24.60 |
| dynorphin-processing endopeptidase (metallo-type) | M9G.030 | - |
| dithiothreitol-sensitive tetrameric peptidase | M9G.037 | - |
| dispase (Paenibacillus/Bacillus polymyxa) | M9G.055 | - |
| extracellular metallopeptidase (Pseudomonas fluorescens M3/6) | M9G.054 | - |
| fibrinolytic peptidase M5 (Crotalus molossus) | M12.176 | - |
| FALGPA-peptidase (Treponema denticola) | M9G.010 | - |
| glycyl aminopeptidase (Actinomucor elegans) | M9A.012 | - |
| gonadotropin beta-subunit nicking enzyme | M9G.036 | - |
| horrilysin | M12.149 | EC 3.4.24.47 |
| hemorrhagin VRH-1 (Daboia russellii) | M12.165 | - |
| HT-1 peptidase (Crotalus viridis) | M12.171 | - |
| hemorrhagic toxin I (Crotalus ruber) | M12.175 | - |
| hemorrhagic factor a (Trimeresurus mucrosqamatus) | M12.181 | - |
| hemorrhagic metallopeptidase a (Trimeresurus mucrosquamatus) | M12.182 | - |
| hemorrhagic metallopeptidase b (Trimeresurus mucrosquamatus) | M12.183 | - |
| halylysin b | M12.307 | - |
| halylysin c | M12.308 | - |
| hemorrhagic toxin I (Gloydius halys blomhoffii) | M12.309 | - |
| hepatitis B virus binding factor | M9G.040 | - |
| hementin (Haementeria ghilianii) | M9G.052 | - |
| insulin-cleaving periplasmic peptidase (Acinetobacter calcoaceticus) | M9G.047 | - |
| leucolysin | M12.136 | EC 3.4.24.6 |
| matrix metallopeptidase-23A | M10.037 | - |
| metallopeptidase B (Bothrops moojeni) | M12.169 | - |
| moojeni peptidase A | M12.345 | - |
| Met-Xaa dipeptidase | M9B.004 | EC 3.4.13.12 |
| mitochondrial carboxypeptidase | M9E.003 | - |
| membrane Pro-Xaa carboxypeptidase | M9E.004 | EC 3.4.17.16 |
| metallopeptidase QG (Escherichia coli) | M9G.021 | - |
| magnolysin | M9G.025 | EC 3.4.24.62 |
| magaininase | M9G.028 | - |
| metallopeptidase ShpII (Staphylococcus hyicus) | M9G.034 | - |
| najalysin | M12.167 | - |
| neuron-specific aminopeptidase | M9A.011 | - |
| neuron-specific aminopeptidase-2 | M9A.013 | - |
| neutral endopeptidase (Aspergillus oryzae) | M9G.009 | - |
| neutral endopeptidase (Micrococcus caseolyticus) | M9G.018 | - |
| NPS peptidase (Saccharomonospora canescens) | M9G.060 | - |
| ophiolysin | M12.152 | EC 3.4.24.51 |
| peptidyl-dipeptidase B | M9D.001 | EC 3.4.15.4 |
| proline-specific peptidyl-dipeptidase (Streptomyces) | M9D.002 | - |
| peptidase Ci (Escherichia coli) | M9G.022 | - |
| procollagen II N-peptidase | M9G.039 | - |
| peptidase Thr-N | M9G.044 | - |
| partitagin (Hippasa partita) | M9G.057 | - |
| prothrombin activator (Dispholidus typus) | M9G.061 | - |
| prothrombin activator (Thelotornis sp.) | M9G.062 | - |
| subfamily M14D nonpeptidase homologue | M14.954 | - |
| succinyl-tri-alanyl-p-nitroaniline hydrolase | M9G.005 | - |
| triflamp (Trimeresurus flavoviridis) | M12.316 | - |
| tripeptide aminopeptidase | M9A.002 | EC 3.4.11.4 |
| tryptophanyl aminopeptidase (Trichosporon cutaneum) | M9A.008 | - |
| Xaa-Trp aminopeptidase | M9A.007 | EC 3.4.11.16 |
| Xaa-Arg dipeptidase | M9B.001 | EC 3.4.13.4 |
| ZPA-processing enzyme | M9G.051 | - |
| EGF-like module containing mucin-like hormone receptor-like 1 | P02.954 | - |
| SERINE PEPTIDASES | ||
| archealysin | S9G.064 | - |
| apoptotic serine peptidase AP24 | S9G.069 | - |
| beta-secretase Matsumoto | S9G.058 | - |
| clipsin | S9G.014 | - |
| collagenolytic endopeptidase (Entomophthora) | S9G.036 | - |
| cryptolepain (Cryptolepis buchanani) | S9G.106 | - |
| CP790 peptidase (Lactobacillus helveticus CP790) | S9G.114 | - |
| coagulant peptidase (Trimeresurus flavoviridis) | S9G.117 | - |
| CLE-processing peptidase | S9G.119 | - |
| crinumin (Crinum asiaticum) | S9G.122 | - |
| dog pancreatic collagenase | S9G.002 | - |
| dipeptidyl-peptidase IV beta | S9G.084 | - |
| elastase-like enzyme, platelet | S9G.005 | - |
| endopeptidase So | S9G.038 | EC 3.4.21.67 |
| extracellular serine endopeptidase (Arthrobacter) | S9G.049 | - |
| erythrocyte membrane high molecular mass peptidase | S9G.072 | - |
| euphorbain | S9G.108 | - |
| fibroblast elastase | S9G.006 | - |
| flavovilase (Trimeresurus flavoviridis) | S9G.089 | - |
| glycylprolyl peptidase (Bacteroides gingivalis) | S9C.001 | - |
| guanidinobenzoatase | S9G.013 | - |
| habutobin | S9G.101 | - |
| hurain | S9G.110 | - |
| hevain (Hevea brasiliensis) | S9G.115 | - |
| Hag-protease (Hippasa agelenoides) | S9G.120 | - |
| ingobsin | S9G.023 | - |
| jerdonobin (Trimeresurus jerdonii) | S9G.087 | - |
| jerdofibrase (Trimeresurus jerdonii) | S9G.088 | - |
| leucyl endopeptidase (Spinacia oleracea) | S9G.031 | EC 3.4.21.57 |
| Mcpt2-rs2a peptidase (Mus musculus) | S01.468 | - |
| Mcpt2-rs2c peptidase (Mus musculus) | S01.469 | - |
| Mcpt8-rs4 peptidase (Mus musculus) | S01.471 | - |
| macrophage chymotrypsin-like peptidase | S9G.009 | - |
| metridin | S9G.034 | EC 3.4.21.3 |
| M003 endopeptidase (Bothrops moojeni) | S9G.092 | - |
| MSP 1 endopeptidase (Bothrops moojeni) | S9G.093 | - |
| MSP 2 endopeptidase (Bothrops moojeni) | S9G.094 | - |
| nuclear histone endopeptidase | S9G.018 | - |
| okinaxobin II (Trimeresurus okinavensis) | S9G.100 | - |
| peptidyl-glycinamidase | S9F.001 | EC 3.4.19.2 |
| peptidase V (Escherichia coli) | S9G.041 | - |
| peptidase Mi (Escherichia coli) | S9G.042 | - |
| peptidase Fa (Escherichia coli) | S9G.043 | - |
| peptidase VI (Escherichia coli) | S9G.050 | - |
| profilaggrin endopeptidase 1 | S9G.054 | - |
| peptidase In (Escherichia coli) | S9G.063 | - |
| plant Asp/Glu serine endopeptidase | S9G.079 | - |
| PofibS endopeptidase (Philodryas olfersii) | S9G.103 | - |
| similar to natural killer cell protease 1 (Rattus norvegicus) (but not S01.380) | S01.928 | - |
| snake venom coagulation factor X activator, serine-type (Bungarus fasciatus, Cerastes vipera, Ophiophagus hannah) | S9G.025 | - |
| serine endopeptidase (Alternaria) | S9G.035 | - |
| serine endopeptidase (Pseudomonas) | S9G.040 | - |
| SP220K peptidase | S9G.081 | - |
| soluble dipeptidyl-peptidase IV | S9G.083 | - |
| seaprose (Aspergillus melleus) | S9G.107 | - |
| solanain (Solanum elaeagnifolium) | S9G.109 | - |
| serine endopeptidase (Rubrivivax gelatinosus) | S9G.121 | - |
| tryase | S9G.012 | - |
| thymus chromatin endopeptidase | S9G.016 | - |
| thermostable serine endopeptidase (Sulfolobus) | S9G.055 | - |
| thrombocytin | S9G.062 | - |
| wrightin (Wrightia tinctoria) | S9G.116 | - |
| Nysius proteinase | S9G.118 | - |
| PEPTIDASES OF UNKNOWN CATALYTIC TYPE | ||
| cathepsin F (old) | U9G.001 | - |
| calmitine-specific mitochondrial peptidase | U9G.031 | - |
| cancer procoagulant | U9G.066 | EC 3.4.22.26 |
| dipeptidylaminopeptidase dDAP | U9C.001 | - |
| dibasic processing endopeptidase (unsequenced) | U9G.007 | - |
| D-aspartyl endopeptidase | U9G.055 | - |
| ES-31 antigen (Mycobacterium tuberculosis) | U9G.065 | - |
| Glu-Glu dipeptidase | U9B.003 | EC 3.4.13.7 |
| LD-dipeptidase (Bacillus sphaericus) | U9B.005 | - |
| Lys-D-Ala carboxypeptidase | U9E.004 | - |
| leulysin | U9G.008 | - |
| LPXTGase (Streptococcus pyogenes) and similar | U9G.054 | - |
| mytilidase | U9G.011 | - |
| miniglucagon endopeptidase | U9G.053 | - |
| N-formylmethionyl-peptidase | U9F.002 | EC 3.4.19.7 |
| nuclear-scaffold peptidase activity | U9G.060 | - |
| peptidyl-D-amino acid hydrolase (cephalopod) | U9B.004 | EC 3.4.13.17 |
| peptidase yscJ | U9G.012 | - |
| prolyl endopeptidase (Spinacia) | U9G.029 | - |
| prelamin endopeptidase | U9G.041 | - |
| peptidase C (mammalian) | U9G.044 | - |
| peptidase E (mammalian) | U9G.046 | - |
| substance P endopeptidase (of CSF) | U9G.033 | - |
| sea urchin 41 kDa collagenase/gelatinase | U9G.050 | - |
| salivary glutaminyl endopeptidase | U9G.070 | - |
| transthyretin | U9G.071 | - |
