Alignment for family S6
3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 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 # # # 1 -----------------------------------------------PMIDFSV---VD---VNKRIGTLV-DPQYIVSVKH------AHQYMNDFYFGHYNG---------HRDVSNDENKYSVVTQNN--------VNSSEKWDVNK--RL-------DDYNMPRLNKFVTEVAPTTPTLAGDDLET---------YKDKEKYPSFVRVGAGRQLVYEKGSRHV----EGNEHGEDLKDLSV----------AYNYAIGGTPYEGINIDPSQS--------KKGLIGFGDSRKDHVIDT-KILLSQAPLTNYGVLGDSGSPLFAFDKQQNKWIFIGPYTYW----------AGYEKKSWQEWNIYKTTFADGIKNRDNAKPVPFSNKEY----RWTNTTNHQSEIKNTDHTITVTLPSDPDRLVNYQKE-----------------E----NKNTGQ-------NVIFEGN--GNSKNTLVLENNINQGAGGLFFKGN--YEVKGTT-DNITWVGGGIDVAEGKTVTWKVHNPEKDHLAKIGKGKLIVEGKGDNKGSLKVGDGTVVLKQQTTTGQ--HAFASVGIVSGRSTVVLNDDKQVDP----NSIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVNHNMTNASNITITGESLITDPKK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 1 2 ALVRDDVDYQIFRDFAENKGKFFVGATDLSVKNKRGQNIGNALSN-VPMIDFSV---AD---VNKRIATVV-DPQYAVSVKH------AKAEVHTFYYGQYNG---------HNDVADKENEYRVVEQNN--------YEPHKAWGASNLGRL-------EDYNMARFNKFVTEVAPIAPTDAGGGLDT---------YKDKNRFSSFVRIGAGRQLVYEKGVYHQ----EGNEKGYDLRDLSQ----------AYRYAIAGTPYKDINIDQTMN--------TEGLIGFGNHNKQYSAEELKQALSQDALTNYGVLGDSGSPLFAFDKQKNQWVFLGTYDYW----------AGYGKKSWQEWNIYKKEFADKIKQHDNAGTVK-GNGEH----HW-KTTGTNSHIGST-----------AVRLAN--NE-----------------G----DANNGQ-------NVTFEDN--G----TLVLDQNINQGAGGLFFKGD--YTVKGAN-NDITWLGAGIDVADGKKVVWQVKNPNGDRLAKIGKGTLEINGTGVNQGQLKVGDGTVILNQKADADKKVQAFSQVGIVSGRGTLVLNSSNQINP----DNLYFGFRGGRLDANGNDLTFEHIRNVDEGARIVNHNTDHASTITLTGKSLITNPNSLSVHSIQNDYDEDDYSYYYRPRRPIPQGKDLYYKNYRYYALKSGGSVNAPMPENGVAENNDWVFMGYTQEEAKKNAMNHKNNQRISGFSGFFGEENGKGHNGALNLNFNGKSAQNRFLLTGGANLNGKISVTQGNVLLSGRPTPHARDFVNKSSARKDAHFSKNNEVVFEDDWINRTFKAAEIAVNQSASFSSGRNVSDI-TANITATDNAKVNLGYKNGDEVCVRSDYTGYVTCNTGNLSDKALNSFDATRINGNVNLNQNAALVLGKAA 2 3 -------------------------ATNVEVRDKKNQSLGSALPNGIPMIDFSV---VD---VDKRIATLV-NPQYVVGVKH------VSNGVSELHFGNLNGNMNNGNAKSHRDVSSEENRYYTVEKNNFPTENVTSFTTKEEQDAQK--RR-------EDYYMPRLDKFVTEVAPIEASTANNNKGE---------YNNSDKYPAFVRLGSGSQFIYKKGSRYQLILTEKDKQGNLLRNWDVGGDNLELVGNAYTYGIAGTPYK-VN----HE--------NNGLIGFGNSKEEHSDP--KGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFW----------AGYNKKSWQEWNIYKHEFAEKIYQQYSAGSLTGSNTQY----TW-QATGSTSTITGGGEPLSVDLTD---------GK-----------------D----KPNHGK-------SITLKGS--G----TLTLNNHIDQGAGGLFFEGD--YEVKGTS-DSTTWKGAGVSVADGKTVTWKVHNPKYDRLAKIGKGTLVVEGKGKNEGLLKVGDGTVILKQKADANNKVQAFSQVGIVSGRSTLVLNDDKQVD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 3 4 GHTYFGIDYQYYRDFAENKGKFTVGAQNIKVYNKQGQLVGTS-MTKAPMIDFSV---VS---R-NGVAALV-ENQYIVSVAH---NVG--Y--TDVDFG-----------AEGNNPDQHRFTYKIVKRNNY--------------------KKDNLHPYEDDYHNPRLHKFVTEAAPIDMTSNMNGST----------YSDRTKYPERVRIGSGRQFWR-----------NDQDKGDQVAG-------------AYHYLTAGNTHNQRGAGNGYSYLGGDVRKAGE---------------------YGPLPIAGSKGDSGSPMFIYDAEKQKWLINGILREG----------NPFEGKE-NGFQLVRKSYFDEIFERDLHTSLYTRAGNGVYT--------ISGNDNGQGSITQKSGIPSEIKITLANMSLPLKEKDKVHNPRYDGPNIYSPRLNNGE-------TLYFMDQKQG----SLIFASDINQGAGGLYFEGN--FTVSPNS--NQTWQGAGIHVSENSTVTWKVNGVEHDRLSKIGKGTLHVQAKGENKGSISVGDGKVILEQQADDQGNKQAFSEIGLVSGRGTVQLNDDKQFDT----DKFYFGFRGGRLDLNGHSLTFKRIQNTDEGAMIVNHNTTQAANVTITGNESIVLPNGNNINKLDY--------------------------------------------------------------------------RKEIAYNGWFGETDKNKHNGRLNLIYKPTTEDRTLLLSGGTNL--KGDITQTKGKLFFSGRPTPHAYNHLN-----KRWSEMEGIPQGEIVWDHDWINRTFKAENFQIKGGSAVVSRNVSSIEGNWTVSNNANATFGVVPNQQNTICTRSDWTGLTTCQKVDLTDTKVINSIPKTQINGSINLTDNATA 4 5 ------------------------------------NVTGTL---SISMPDFSS---VA---T-EGYATLI-SPQYIVSVKH---NKG--Y--NTVSFG-----------------DGQN-SYTIVNRNE---------------------DP----S--RDFHTPRLNKLVTEVSPADAISTGDSSNF---------YTDSERYTAFVRLGSGRQFIK-----------NEDGTLTQLAA-------------GYSYLTGGT----LKAPVVYQ--NGNS-LKAT---TPDLFN----------SDMGLLPTTAQPGDSGSPLFAWDSWTGKWVLIGVQTAI-------------STSW-SYWAAIPVSDIQAIINDDSDGTISFLDSAG-AL-IW-----TYNSTDGTGTISQGNTTYT----MHGTKD-----------------G----NLDAGK-------NLTFTGD-DG----LILLRDNVDQGAGTLTFNSN--YTVSTDN--NSTWMGGGLDIAEGTSVTWQVNGVSGDNLHKIGAGTLIVNASGINEGGLKVGDGTTVLDQQPDKDGNVQAFSSVNIASGRATVVLADSNQVDP----DNISWGYKGGTLDLNGNNLTFHQIKAADYGAVIANTA-DST-STVTLSYSLNSNDVNINNWAGLN----SK-----------GTPGDLYVYNNTYTNTTDYFILKTDGYYGYYPTNQSSSDIWEYVGHDQDAAQKLVADRYNSSGY-----LYHGQFTGNLNIVNTVASGATGSFVMDGSADI-SGSFTQENGRLTLQGHPVIHAYNSQSIADTVASTGDDSVLTQPTSFTQSDWENRSFTFGALNLKNTDFSLGRN-ATLNTVIQAEN-SVVTLG---------------------------------------------------- 5 6 AILSNDIPFQTYRDFAENKGMFAPGNKNIPIYDKNGNIKNIL---TIPVPDFSS---IS---T-LGIATLV-DAQHIASVKH---NGG--Y--TNVSFG-----------------VGDN-LYTIVNRNN---------------------NP----S--VDFHAPRLNKLVTEVAPMEVAKIDV--GN---------KFDEKRYTQFIRIGSGSQIIT-----------ESNKT---IAN-------------PYAVLTGGT----VGDITYKNWWGGVY-MSP----TGNLGDH-----------MGPLPNHPQPGDSGSPLFAYDNIDKKWVLFGVFYGY-------------NDYN-SFYTPIQLEQLNSIASTESDGIIVSQSND--VF-HW-----SFDKKNGLGKIQQGNHTYE----MHGRLS-----------------D----NLDNGK-------NITFTGN-SG----HILLDNDIDQGAGSLTFLTD--YTVGTSN--NSTWIGGGLDIHKNATVTWKVNGQKNDNLHKIGEGTLIVNASGINEGGLKVGNGVTVLNQQPDAYGRVQAFSSVNIASGRPTVVLSNDKQINP----DNITWGYRGGVLDVNGNNLTFHILNAADHGAIISNSS-DKT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEITL----------------------------------------------------- 6 7 --VNNELGYQSFRDFAENKGMFRPGATNIAIYNKQGELVGTL--EKAAMPDFSS---VN--SG-SGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------YGES-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPAAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNTWVLVGVLSAG----------NGAGGRG-NNWAVIPLDFIRQKFNEDNDAPVTFRTSEGGAL-EW-----GFNSSTGAGTLTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFLGQ-NG----QIDLKDNVAQGAGSLTFHND--YTVATSN--NSTWTGAGIIVDKGVFVNWQVNGVKGDNLHKIGEGTLTIQGTGINEGGLKAGDGTVVLKQQADSNGQVQAFSSVNIASGRPTVVLTDDRQVNP----DNISWGYRGGILDVNGNDIGFHEIKAADYGAQIHNGS-NKN-AIISL-----VMHDVIKWTGK-D----TP-----------RILGRVYEYFNDETQKTEFFILKTSS-IAWSPSPGEKIFPDMFRG---ADYFNTLEDADKEARK-----NTQYIFHGKLTGNISFNPKSAGTFVMDGSADM-SGTFTRENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLNQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-AMLNTTLEATD-STVTLG---------------------------------------------------- 7 8 --VNNELGYQSFRDFAENKGMFRPGATNIAIYNKQGELVGTL--EKAAMPDFSS---VN--SG-SGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------YGES-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPAAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNTWVLVGVLSAG----------NGAGGRG-NNWAVIPLDFIRQKFNEDNDAPVTFRTSEGGAL-EW-----GFNSSTGAGTLTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFLGQ-NG----QIDLKDNVAQGAGSLTFHND--YTVATSN--NSTWTGAGIIVDKGVFVNWQVNGVKGDNLHKIGEGTLTIQGTGINEGGLKAGDGTVVLKQQADSNGQVQAFSSVNIASGRPTVVLTDDRQVNP----DNISWGYRGGILDVNGNDIGFHEIKAADYGAQIHNGS-NKN-AIISL-----VMHDAIKWTGK-D----TP-----------RILGRVYEYFNDETQKTEFFILKTSS-IAWSPSPGEKFFPDMFRG---ADYFNTLEDADKEARK-----NTQYIFHGKLTGNISFNPKSAGTFVMDGSADM-SGTFTRENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLNQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-AMLNTTLEATD-STVTLG---------------------------------------------------- 8 9 ---------------------FRPGEKNIAIYNKQGELVGTL--DKAAMPDFSS---TN---T-SGIATLI-NPQYVASVKH---NVG--Y--QNVTFG-----------------YKDSTSYILVDRNE---------------------HS----N--LDFHVPRLNKLVTEVTPSNITAQGAINGA---------YLDKNRYPAFYRIGSGVQYIK-----------DEEGNLTWLSG-------------AYSYLTGGT----VGNPSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEDGTL-EW-----SFNSSTGAGTLTQGTTIYA----MHGQQG-----------------N----DLNAGK-------NLEFLGQ-NG----QIDLKDSVVQGAGSLTFHND--YTVATSN--NSTWTGAGIIVDKGVSVNWQVNGVKGDDLHKIGEGTLTVQGTGINEGGLKVGDGNVILNQQSDNKGQVQAFSSVNIASGRPTVVLTDDRQVNP----DNITWGYRGGILDVNGNDIAFHEISAADYGAQIYNSG-NKN-AAISL-----VKHDVIQWTGK-D----TQ-----------RILGRVYEYFNDETKKAEFFILNTTS-TGWYPTPGEKYLPDMFRG---ADYFDTLEDADKEVKK-----NTQYIYHGKLTGNISFNPESVGTFVMDGSADM-SGTFTYENGRLTLQGHPVIHAYNTQSVADKLAASGDNSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTMLEATD-STVTLG---------------------------------------------------- 9 10 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NEG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AS----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGSTTYA----MHGQQG-----------------N----DLNAGK-------NLIF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 10 11 ---------------------FRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRND---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGSTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGA-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDINGNSLTFHQLKAADYGAVLANNA-DKR-ATITLDYALRADKVALNGWSE-S----RK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGSADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTMVEATD-STITLG---------------------------------------------------- 11 12 ---------------------FRPGATNIAIYNKQGGLVGTL--DKAAMPDFSA---VD--SK-IGVATLI-NPQYIASVKH---NEG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AS----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGA-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTW------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 12 13 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGGLVGTL--DKAAMPDFSA---VD--SK-IGVATLI-NPQYIASVKH---NEG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AS----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 13 14 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGGLVGTL--DKAAMPDFSA---VD--SK-IGVATLI-NPQYIASVKH---NEG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AS----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 14 15 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGGLVGTL--DKAAMPDFSA---VD--SK-IGVATLI-NPQYIASVKH---NEG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AS----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 15 16 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGGLVGTL--DKAAMPDFSA---VD--SK-IGVATLI-NPQYIASVKH---NEG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AS----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 16 17 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-CYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVDPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTKMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 17 18 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 18 19 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 19 20 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 20 21 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTKMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 21 22 GTVNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTKMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLGDSRVFIDKNDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQSVL------ 22 23 ------------------------------------------------MPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTKMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTSALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 23 24 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTKMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTSALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 24 25 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTKMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTSALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 25 26 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTKMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTSALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 26 27 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGEFVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTKMGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTSALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 27 28 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 28 29 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 29 30 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIVVDNGVSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNV-DKR-ATITLDYALRADKVALNGWSE-S----GK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGAADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 30 31 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGGLVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 31 32 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGGLVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVADA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGVLTQGSTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGA-NG----QINLKDSVSQG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 32 33 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGGLVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVADA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGVLTQGSTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGA-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGGGIIVDKDASVTWQVNGEKGDNLHKIGEGTLIVQGTGVNEGGLKVGDGTVVLNQQADSSGKVQAFSSLNIASGRPTVVLADNRQVDP----DNISWGYRGGVLDVNGNDLSFHNISAADYGAELHNSS-NKE-ARISLVMPDAIEWEGKDTPRI-L----GQ-----------AYKYFNSETQKTEFFILNTGSLGWRP-SPEEKLLPEFLRGADYFSSLADANKEAGKNKQSVFHG-----KLTGNISFNADHIGKFIMDGSADISGSFSKEN-GRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFTQDDWENRTFSFGSLVLKNADFGLGRNATLNTIIQ-ADNSSVTLG------------------------------------------------------------- 33 34 ------------------------------------------------------------------MATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVADA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 34 35 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGGGIIVDKDASVTWQVNGEKGDNLHKIGEGTLIVQGTGVNEGGLKVGDGTVVLNQQADSSGKVQAFSSLNIASGRPTVVLADNRQVDP----DNISWGYRGGR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 35 36 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQMGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTVGGIIVDKDASVTWQVNGEKGDNLHKIGEGTLIVQGTGVNEGGLKVGDGTVVLNQQADSSGKVQAFSSLNIASGRPTVVLADNRQVDP----DNISWGYRGGVLDVNGNDLSFHNISAADYGAELHNSS-NKE-A--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 36 37 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NEG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AS----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQIGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGAGGRG-NNWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGVLTQGSTTYA----MHGQQG-----------------N----DLNAGK-------NLIFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGGGIIVDKDASVTWQVNGEKGDNLHKIGEGTLIVQGTGVNEGGLKVGDGTVVLNQQADSSGKVQAFSSLNIASGRPTVVLADNRQVDP----DNISWGYLG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 37 38 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDFSA---VD--SE-IGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DGEN-RYNIVDRNN---------------------AP----S--LDFHAPRLDKLVTEVAPTAVTAQGAVADA---------YLDKERYPVFYRLGSGTQYIK-----------DSNGQLTQIGD-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------KLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 38 39 --VNNELGYQLFRDFAENKGMFRPGATNIAIYNKQGELVGTL--DKAAMPDLSS---VN--SG-SGVATLI-NPQYIASVKH---NGG--Y--TNVSFG-----------------DSEN-RYNIVDRNN---------------------AT----S--LDFHAPRLDKLVTEVAPTAVTAQGAVAGA---------YKDKERYPVFYRLGSGTQYIK-----------NSNGQLTQVGG-------------AYSWLTGGT----VGSLSSYQ--NGEM-ISTS---SGLVFDY---------QLNGAMPIYGEAGDSGSPLFAFDTVQNKWVLVGVLTAG----------NGPGGRG-NNWAVIPLDFIEQKFNEDNDAPVTFSSSEGGVL-EW-----SFDSSTGVGTLTQGTITYD----MHGQLG-----------------N----DLNAGK-------NLEFLGQ-NG----QIELKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIIVDKGVSVNWLVNGEAGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLSQQADSKGQVQAFSSVNIASGRPTVVLTDDRQVNP----DTISWGYRGGILDVNGNDLTFHQLKAADYGAVLANNS-DNH-ASITL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 39 40 ----------------------------------RGELVGTL--NKAAMPDFSS---VNVKSN-PGVATLI-NPQYVASVKH---NGG--Y--KNVSFG-----------------DGEN-RYNIVDRNE---------------------HG----S--QDFHAPRLDKLVTEVIPASVTEEGQKTNA---------YANTERYTAFYRAGSGTQYIK-----------DKSGNVTQISG-------------AYSYLTGGT----VGAPSS----SDHI-IASS---PGNVFN----------PINGPLSSYGAPGDSGSPLFAYDSWQKKWVMVGVLSTW----------TGEHGVN-NRWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGSTTYA----MHGQQG-----------------N----DLNAGK-------NLKFQGQ-NG----QINLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIIVDKGMSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNA-DKR-ATITLDYALRADKVALNGWSE-S----RK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNAAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGSADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTLEATD-STVTLG---------------------------------------------------- 40 41 SIVSAEIDYQIFRDFAENKGAFRPGATDIAIYNKRGELVGTL--NKAAMPDFSS---VNVKSN-PGVATLI-NPQYVASVKH---NGG--Y--KNVSFG-----------------DGEN-RYNIVDRNE---------------------HG----S--QDFHAPRLDKLVTEVIPASVTEEGQKTNA---------YANTERYTAFYRAGSGTQYIK-----------DKSGNVTQISG-------------AYSYLTGGT----VGAPSS----SDHI-IASS---PGNVFN----------PINGPLSSYGAPGDSGSPLFAYDSWQKKWVMVGVLSTW----------TG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 41 42 SIVSAEIDYQIFRDFAENKGAFRPGATDIAIYNKRGELVGTL--NKAAMPDFSS---VNVKSN-PGVATLI-NPQYVASVKH---NGG--Y--KNVSFG-----------------DGEN-RYNIVDRNE---------------------HG----S--QDFHAPRLDKLVTEVIPASVTEEGQKTNA---------YANTERYTAFYRAGSGTQYIK-----------DKSGNVTQISG-------------AYSYLTGGT----VGAPSS----SDHI-IASS---PGNVFN----------PINGPLSSYGAPGDSGSPLFAYDSWQKKWVMVGVLSTW----------TGEHGVN-NRWAVIPLDFIGQKFNEDNDAPVTFRTSEGGAL-EW-----SFNSSTGAGALTQGTTTYA----MHGQQG-----------------N----DLNAGK-------NLEFLGQ-NG----QIDLKDSVSQGAGSLTFRDN--YTVTTSN--GSTWTGAGIIVDKGMSVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNA-DKR-ATITLDYALRADKVALNGWSE-S----RK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNAAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGSADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTMLEATD-STITLG---------------------------------------------------- 42 43 --VNSEISYQLFRDFAENKGLFKPGSTNIPVHNKSGELVGKL--DKAPMPDFSS---VD--SG-IGVATLI-DPQYVVSVKH---NGG--Y--QGVSFG-----------------DGDN-YYSIVDRNN---------------------AP----D--LDFHIPRLNKLVTEVTPTSITSQGAVSGA---------YLDKVRYPVFYRLGSGNQYIK-----------DRNNALDHLSS-------------AYNWLTGGT----VGNPSSYQ--NGEM-LSSS---SGLVFDY---------TRNDVLPIYGEAGDSGSPLFAWDTTLQKWVLVGVLTAG----------NGPGGRA-NNWAVTPLNFVHQKMTEDDGPFVLFDSSDDAPL-TW-----SFDPQTGTGNLTQGNVTYK----MQGKQG-----------------S----DLNAGK-------NIHFSGK-GG----EVKLVDDVFQGAGYLRFLDN--YTVTAIN--NSVWTGAGIIVDKLSTVNWQLNGLKGDNLHKIGEGTLIIEGTGINEGGLKVGAGTVVLNQQSNEEGSTQAFSSVNIAGGTSSVILGNERQINP----DSVSWGYRGGKLDLNGTSATFHKLKAADYGAVLANDD-NENISTITLDYQLKPRDITTHEWDS-S----NR-----------GTVGDLYEYNNTYTRTTDYFILKKSK-YGYFPTTQISDDNWEYLGHELDAAQKLIAKRTNDKSY-----VFHGRLEGNMNVENRVSSEYGGALVLDGSANI-KGTFTQDNGHLVLQGHPVIHAFNSQQTAEHLSAKGDDSVHTQPTSFEQKDWENRDFTFGQLVLNNAYLRLARN-ATLSTNLDANN-SVIALG---------------------------------------------------- 43 44 GTVNSDIDYQLFRDFAENKGHFIAGATNITVTDKNGNVTGIL--DKAPMPDFSP---VS---T-NGVATLI-NPQYVASVKH---NGG--Y--QGVTFGNKSQ-----------NPDNDHFNYKIVDRNN---------------------HT----K--LDFHAPRLNKVVTETAPSAITEQGATPGA---------YLDKERYPVFYRLGSGTQYIK-----------DASGNLVKVGA-------------AYSYLTGGT----VPNLSSYN--NGQM-ISAA---SGTVFNY---------STNGALPIYGEAGDSGSPLFGWDTTLNKWVLVGVLTAG----------NGPGGRA-NNWAVLPLDFIQTTLDEDNDAPVIYDSVNGGAL-DW-----VFDSATGIGTLTQGITKFE----MHGQKA-----------------A----DLDAGK-------NLIFSGV-DG----KLNLKNDVHQGAGALTFKND--FTVASDS--GNIWTGAGVIVDKDATVKWQINGQHNDALHKIGEGTLYVNGIGTNPGDLRVGDGTVILAQQADENGNKQAFNKLTITSGRPTVVLKDAEQVNP----DNIYFGYRGGRLDLNGNNLSFSRIKNADSGANIVNNN-KEI-ASL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 44 45 SIVSAEIDYQIFRDFAENKGAFRPGATDIAIYNKRGELVGTL--NKAAMPDFSA---VN--IA-DGASTLI-DPQYVASVRH---NSDWHF--NSLRFG-----------------DGDN-EYKSVSRND---------------------HPYGADS--RDFALPRLSKLVTEVVPATVTT--ASYKD---------IADPSRFPLFYRVGAGTQYTQIPGD-------TSKESYTSING-------------AYAYLTGGL----LPSVSA-------V-PSITLSDYGTVYELLGHTIKNVNAFDDTMVSRPTAGDSGSPVFAWDAVNHQWVLVGVHTGGQSRNDINGTNNPATGKG-YATA-IPLGYVTQIIQENYDAPVMFDALVGSSL-SW-----TYDNTSGTGALTQGSSEYA----MHGQQG-----------------D----DLNAGK-------NLIFMGQ-NG----RVDLKDSVLQGAGSLTFRDN--YTVTTTN--GSTWTGAGIIVDRKASVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNA-DKR-ATITLDYVLRAEKVTLNNWSD-S----RR-----------GDVGSLYKYDNPYTRTTDYFILKQNT-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNTAGY-----LFHGQLKGNLNVDNRLPEGVTGALVMDGSADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQADWENRSFTFDRLSLKNTDFGLGRN-ATLNTMLEATD-STVTLG---------------------------------------------------- 45 46 SIVSAEIDYQIFRDFAENKGAFRPGATDIVIYNKRGELVGTL--NKAAMPDFSA---VN--IA-DGASTLI-DPQYVASVRH---NSDWHF--NSLRFG-----------------DGDN-EYKSVSRND---------------------HPYGADS--RDFALPRLSKLVTEVAPATVTT--ASYKE---------IADSSRFPLFYRIGAGSQYTQIPGD-------TSKESYTSING-------------AYAYLTGGG----VPSVSA-------V-SSMGLSGYGTVYELLGHTIKNVNDFDDTMVSRPTAGDSGSPVFGWDAVNHQWVLVGVHTGGASRNDIDGTNNPATGKG-YATA-IPVSYVTQIIQGNYDAPVMFDALAGNSL-LW-----TYDNTTGTGALTQGSSEYS----MHGQLG-----------------D----DLNAGK-------NLIFMGQ-NG----QVDLKDPVSQGAGSLTFRDN--YTVTTSN--RSTWTGAGIIVDREASVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGTVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDDRQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLTNNA-DKR-ATITLDYALQADKVTLNSWSG-S----RK-----------GTVGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNAAGY-----LFHGQLKGNLNVNSRLPEGVTGALVMDGSADM-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTTLEATD-STVTLG---------------------------------------------------- 46 47 ------------------------------------------------------------------MATLI-NPQYVASVKH---NGG--Y--KNVSFG-----------------DGEN-RYNIVDRNE---------------------HS----S--VDFHAPRLDKLVTEVAPANVTS--ASQTE---------ILEPSHFMAFYRLGSGNQYIQ-----------NADGNQTHISG-------------AYGYLTGGT----LPA-SFYS--HGGA-SGIQVYLGGNLGNY------------GAMTSFGQSGDSGSPLFGWNAVSGQWELIAVYSAK----------GG--GTN-MIYKLIPRDFLSQIYSEDNDSPITFSTLTGGAL-EW-----TFDSNAGIGALTQGSTTYA----MHGQQG-----------------N----DLNAGK-------NLIFMGQ-NG----RVDLKDSVSQGAGSLTFRDN--YTVTTTN--GSTWTGAGIIVDKKASVNWQVNGVKGDNLHKIGEGTLTVQGTGINEGGLKVGDGKVVLNQQADNKGQVQAFSSVNIASGRPTVVLTDERQVNP----DTVSWGYRGGTLDVNGNSLTFHQLKAADYGAVLANNA-DKR-ATITLDYALRADKVALNGWSE-S----RK-----------GTAGNLYKYNNPYTNTTDYFILKQST-YGYFPTDQSSNATWEFVGHSQGDAQKLVADRFNAAGY-----LFHGQLKDNLNVDNRLPEGVTGALVMDGSADI-SGTFTQENGRLTLQGHPVIHAYNTQSVADKLAASGDHSVLTQPTSFSQEDWENRSFTFDRLSLKNTDFGLGRN-ATLNTMLEATD-STVTLG---------------------------------------------------- 47 48 ------------------------------------------------MVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQW-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 48 49 ------------------------------------------------MVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 49 50 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 50 51 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTRPANVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 51 52 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTRPANVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 52 53 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQW-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 53 54 ------------------------------------------------MVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 54 55 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 55 56 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPR-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTHPADVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 56 57 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQW-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 57 58 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 58 59 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTRPADVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 59 60 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTRPADVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 60 61 ------------------------------------------------MVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTRPADVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 61 62 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTRPADVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 62 63 -TVGGNNPYQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTRPADVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLGDSRVFIDKKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQSVL------ 63 64 --------------------------------------------------------------N-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQW-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 64 65 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 65 66 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQW-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 66 67 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------GYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGI------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSS-DKT-ANITLDYQTRPADVKVNEWSS-S----NR-----------GTVGSLYIYNNPYTHTVDYFILKTSS-YGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGY-----LYHGKLLGNINFSNKATPGTTGALVMDGSANM-SGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTTIQADN-SSVTLG---------------------------------------------------- 67 68 --------YQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DKAPMVDFSS---VNVSSN-PGVATLI-NPQYIASVKH---NKG--Y--QSVSFG-----------------DGQN-SYHIVDRNE---------------------HS----S--SDLHTPRLDKLVTEVAPATVTS--SSTAD---------ILNPSKYSAFYRAGSGSQYIQ-----------DSQGKRHWVTG-------------EYGYLTGGI----LPT-SFFY--HG-S-DGIQLYMGGNIHDH------------SILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGV------------GGGTN-LIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPL-QW-----KFDSSTGTGSLKQGSDEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-NG----QIDLENSVTQGAGSLTFTDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQQVNP----DNISWGYRGG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 68 69 SVVSGNIPYQTYRDFAENKGQFQAGTTNIPIFNKNGDLVGRL--DKAPMIDFSS---VNVGSN-PGVATLI-NPQYVASVKH---NRG--Y--QGVSFG-----------------DGEN-RYNIVDRNE---------------------HG----S--ADFHAPRLNKLVTEIAPAMVTG--ASQAE---------ILDPSKFSALYRMGSGSQYIQ-----------DAQGKWNWVSG-------------AYGYLTGGL----LPT-SFFT--HG-A-GGIQAYMGGNINDH------------SVMPSFGQAGDSGSPLFGWNTTRSQWELIGVYSAV------------GGGTN-MIYQLIPQNFLSQIYSEDNDAPVFFNPSVGSPL-HW-----KFDSSTGSGSLTQGSTEYA----MHGQKG-----------------S----DLNAGK-------NLTFLGH-DG----QIVLDNSVSQGAGSLTFHDD--YTVTTSN--GSTWTGAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGQVQAFSSVNIASGRPTVVLADNRQVNP----DNISWGYRGGVLDVNGNDLTFHKLNAADYGAVLGNSS-DKM-ASITLDYQMHPADVKINEWSS-S----KK-----------GTAGALYVYNNPYTHTVDYFILKTND-YGWFPTGQVSNEHWEYIGHDQSSAQTLLADRTNSKGY-----LYHGRLLGNINVSNKVLPDTTGALVLDGSANI-RGSFSQENGRLTIQGHPVIHASTSQSVANTVASQGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTHILADN-SSVTLG---------------------------------------------------- 69 70 SVVRGDIPYQTYRDFAENKGQFSVSQTDISIFDKEKNAIAIL--NNAPMIDFSS---VN--SG-SGVATLI-NPQYVVSVKH---NGG--Y--QNISFG-----------------NGEN-NYHIVDRNN---------------------QN----N--RDFHSPRLNKLVTEVVPSAMTHSGMVSGA---------YLDKKLYSAFYRLGSGTQEIR-----------DVNGNVKTISG-------------AYSYLTGGT----VGFPGSYD--NGRM-ISTNT--NRGLFDT---------AQQGPLGTYPRSGDSGSPLFAYDTTQQEWVLVGVTSSG-------------GGGG-TNWAVVDANFVQQKIKEDTNGTVAFVDGQG-PL-QW-----SFESTTGTGFLEQQEIRYQ----MHGKKN-----------------A----DLNAGK-------NLIFQGH-NG----QIDLKDSVYQGAGSLTFNDD--YTVTTSN--GSTWTGAGIIVDKGVSVNWQVNGVKGDNLHKIGEGTLVIQGTGVNEGGLKVGDGTVILNQQADSSGHIQAFSSVNIASGRPTVILSDNQQVNP----DNISWGYRGGILDVNGNDITFHEINASDYGAQLHNSS-NKN-AIISLD----MRDNTIRWTGK-D----TS-----------RIPGRVYEYFNDETQKTEFFILNTKS-SGWSPSPGEKLLPKMLRG---ADYFSSLEDANKEAAK-----NKQLIYHGKLTGNINFDAGNIGKFIMDGSADV-MRSFSKEDGRLTMQGHPVIHAYSSKAVADKVAATGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRN-ATLNTIIQADN-SSVTLG---------------------------------------------------- 70 71 ------LPYQTYRDFSENKGEFSPGTTNIPLYNKNGTLEQVL--DKAPMIDFSS---VNIDGS-PGVATLV-NPHYIVSVKH---NKG--Y--KNPRFG--------------------TSTYTIVDRNN---------------------NP----ASKIDFHAPRLNKIVTDVVPAEMTDAGTVNGI---------YKNKDRFPVFYRTGSGTQYIK-----------EKSVTLRHLSG-------------AYSYLTGGT----VGNPSSYQ--KGEM-ITVS---SGQIYN----------KNNGPMASYGEAGDSGSPLFGWDTTKKQWVLVGALTAG----------NGAGGNA-NNWVVIPVDFVESKINEDTD-PEVNNVFG--LI-EW-----TFDSAKGSGLLKQGDQQWN----MHGILE------------------N---NLDKGK-------NLIFSGD-DA----RIVLKNDVDQGAGTLTFNGN--YTVSTDD--NETWKGGGVIVNSGKTVTWQVNGITNDNLHKLGEGTLNINSTGVNPGGLNVGDGTVILSQKPDDEGHVQAFSRVAIVSGRPTVVLSDAKQVNP----DNISWGYRGGVLDINGNSLTFHKLNAFDDGATITSNG-DKAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 71 72 ------LPYQTYRDFSENKGEFIPGTTNIPLYNKNGTLEQVL--DKAPMIDFSS---VNIDGS-PGVATLV-NPQYIVSVKH---NKG--Y--KNPRFG--------------------TSTYTIVDRNN---------------------NP----ASKIDFHAPRLNKIVTDVVPAEMTDAGTVNGI---------YKNKDRFPVFYRTGSGTQYIK-----------EKSGTLRHLSG-------------AYSYLTGGT----VGNPSSYQ--KGEM-ITVS---SGQIYN----------KNNGPMASYGEAGDSGSPLFGWDTTKKQWVLVGALTAG----------NGAGGNA-NNWVVIPVDFIESKINEDTD-PEVNNVFG--LI-EW-----TFDSAKGSGLLKQGDQQWN----MHGILE------------------N---NLDKGK-------NLIFSGD-DA----RIVLKNDVDQGAGALTFNGN--YTVSTDD--NETWKGGGVIVNSGKTVTWQVNGITNDNLHKLGEGTLNINSTGVNPGGLNVGDGTVILSQKPDDEGHVQAFSRVAIVSGRPTVVLSDAKQVNP----DNISWGYRGGVLDINGNSLTFHKLNAFDDGATITSNG-DKAT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 72 73 --VGNILPYQTYRDFAQNRGVFQPGASNITLYDKNGNPAGVL--DKVPMMDFSS---VD---K-LGIATLV-NPQYVVSVKH---NGG--Y--QSVRYG--------------------NYTYTIVDRNN---------------------HW----G--LDFHAPRLNKIVTEVIPSEMTHAGTVNNI---------YNDKTRFPVFYRMGSGTQYIK-----------TPSGKLQQIAG-------------GYSYLTGGT----VGSLHSYQ--KGEM-ISTS---SGQIYN----------IANGPMATYGEAGDSGSPLFGWDTTINKWTLVGVLTSG----------NGAGGNG-NNWAVIPVNYVKGILAQDSD-PAVNNTSSE-KI-LW-----NFDSQTGTGSLTQGSQRWD----MHGSVN-----------------GT---NLNNGK-------NLTFLGS-DG----QMMLNNAVDQGAGTLTFDAN--YTVSPST--NETWKGGGIIVNDDHTVDWQVNGVKGDNLHKLGTGTLKVNGTGVNPGGLNVGEGTVILAQRPDSDGNVQAFNIVDIVSGRPTVVLSDDKQVNP----DNIIWDYRGGKLDINGNSLTFHQLNGADDGAILTNSG-KQATVNLDFNKPNATTTVAN---------------------------------------------------------------------------------------------IWHGHFTGNVDVSNAATTSTQNDFVMDGGMNI-QGSFTQQNGRLFIQGHPVIHAASSQAVANKLKTFGDNSVLTQPVSFTQSDWENRQFSMTQLNLNNADFSLARN-ASLSTLINADH-STVTLGSENLYIDLNDGNGAKTTPSFGQSKATNAADQSRFSGRVQLKNGSTL------ 73 74 SVVSENIPYQTYRDFAENKGEFQAGNMGIIIKDKNGNISGIL--SSVSMPDFSA---TD---T-SGIATLV-YPQYLSGVRH---NGG--Y--TGVRFG-----------------NGEN-IYKLVSRNN---------------------AS----D--MDIHTPRLDKLVTEVAPIDAAT---TDVS---------FNKSNRYAAFYRLGSGSQMIK-----------DTNGKNISVSG-------------AYQYLTGGT----VSGLSYYGWFGGTL-MATTADLA---------------SAQGLLPTHTLGGDSGSPLYAYDKLQGKWVLIANLSSG-------------SGKN-ALWSVVSASKIQNIMDSYFDGLVSYDRASHENI-IW-----SFDAKEGVGSLSQGNHSHT----MHGQKG-----------------S----DLNAGK-------DLSFSGH-GG----VIDIRNSVAQGAGSLTFHDD--YTV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 74 75 SVVKGNIPYQTYRDFAENKGVFQAGKSDIIIKDKNGNITGTL--NSAPMPDFSA---TD---T-SGVATLV-SPQYLSGVRH---NGG--Y--TGVRFG-----------------DGEN-LYHLVSRNN---------------------AS----D--MDIHTPRLDKLVTEVVPVGAAS---TDAS---------FNNSRQYSAFYRLGSGSQLIK-----------NDDGKNISITG-------------AYQYLTGGT----VAGLSYYNWFGGTL-MASTADLT---------------SAQGVLPSHTQGGDSGSPLYAYDKAQGKWVLVANLSSG-------------SGKN-ALWSVVSAGRIQNIMDAYSDGLVNYDNTSPENI-IW-----LFDASEGVGSLSQGNEAHT----MHGKKG-----------------N----DLNAGK-------DLSFSGH-NG----VIDIRDNVSQGAGSLTFHDD--YTVTTTN--GSTWTGAGIIVDQNTSVNWQVNGVKGDNLHKIGQGTLIVQGTGVNEGGLKVGDGTVILNQQADSSGQVQAFSSVNIASGRPTVVLADNRQVNP----DNISWGYRGGILDVNGNDLSFHNISAADYGAQLHNSS-DKE-ATVSL-----TIPDAIEWNGK-D----TQ-----------RISGQVYKYFNTESQTTEFFVLKTTS-AGWSPSPAEKHLPEIFRG---ADYFSSLEEANREASA-----DSQLIYHGKLTGNIRFDAGSVGKFVMDGSADI-GGTFSKEDGRLTMQGHPVIHAFNSQSIADKVAATGDGSVLTQPTSFTQDDWESRTFSLGMLELKNTDFGLGRN-AALNTHIQADN-SRVTLG---------------------------------------------------- 75 76 ------LPYQTYRDFAENKGEFRPGAENVPLYDKNGNPVTTL--NKAPMIDFSS---ND---S-TGVATLV-SPQYVVSVKH---NVG--Y--QYVKFG-----------------YADDSSYALVDRNN---------------------HW-------RDFHTPRLNKIVTEVTPLDITNAGTAKGT---------YQNADRFPVFYRVGTGTQYVK-----------DTNGKITYLMG-------------AYSYKTGGI----VNTPAISD--WS---FVTN---TTNT----------------PLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSY----------AGVNGNT-NWYTIIPAGDVKNTMKQDADAPVNTKQGEG-DI-HW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 76 77 ------LPYQTYRDFAENKGEFRPGAENVPLYDKNGNPVTTL--NKAPMIDFSS---ND---S-TGVATLV-SPQYVVSVKH---NVG--Y--QYVKFG-----------------YADDSSYALVDRNN---------------------HW-------RDFHTPRLNKIVTEVTPLDITNAGTAKGT---------YQNADRFPVFYRVGTGTQYVK-----------DTNGKITYLMG-------------AYSYKTGGI----VNTPAISD--WS---FVTN---TTNT----------------PLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSY----------AGVNGNT-NWYTIIPAGDVKNTMKQDADAPVNTKQGEG-DI-HW-----SYDEKTGLGSLTQGSTSWE----MHGNLG-----------------ATWPASLNSGK-------DLTFQGG--G----TVVLENTVNQGAGTLTFDDD--YIVKPVD--TQTWKGGGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKINGTGVNPGSLSVGDGTVILAQRADDNGLSQAFSSVSIVSGRPTLVLNDDKQINP----DNIKWGYHGGKLDINGNSLTFHKLNGADDGAILTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 77 78 ------LPYQTYRDFAENKGEFRPGAENVPLYDKNGNPVTTL--NKAPMIDFSS---ND---S-TGVATLV-SPQYVVSVKH---NVG--Y--QYVKFG-----------------YADDSSYALVDRNN---------------------HW-------RDFHTPRLNKIVTEVTPLDITNAGTAKGT---------YQNADRFPVFYRVGTGTQYVK-----------DTNGKITYLMG-------------AYSYKTGGI----VNTPAISD--WS---FVTN---TTNT----------------PLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSY----------AGVNGNT-NWYTIIPAGDVKNTMKQDADAPVNTKQGEG-DI-HW-----SYDEKTGLGSLTQGSTSWE----MHGNLG-----------------ATWPASLNSGK-------DLTFQGG--G----TVVLENTVNQGAGTLTFDDD--YIVKPVD--TQTWKGGGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKINGTGVNPGSLSVGDGTVILAQRADDNGLSQAFSSVSIVSGRPTLVLNDDKQINP----DNIKWGYHGGKLDINGNSLTFHKLNGADDGAILTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 78 79 ------LPYQTYRDFAENKGEFRPGAENVPLYDKNGNPVTTL--NKAPMIDFSS---ND---S-TGVATLV-SPQYVVSVKH---NVG--Y--QYVKFG-----------------YADDSSYALVDRNN---------------------HW-------RDFHTPRLNKIVTEVTPLDITNAGTAKGT---------YQNADRFPVFYRVGTGTQYVK-----------DTNGKITYLMG-------------AYSYKTGGI----VNTPAISD--WS---FVTN---TTNT----------------PLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSY----------AGVNGNT-NWYTIIPAGDVKNTMKQDADAPVNTKQGEG-DI-HW-----SYDEKTGLGSLTQGSTSWE----MHGNLG-----------------ATWPASLNSGK-------DLTFQGG--G----TVVLENTVNQGAGTLTFDDD--YIVKPVD--TQTWKGGGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKINGTGVNPGSLSVGDGTVILAQRADDNGLSQAFSSVSIVSGRPTLVLNDDKQINP----DNIKWGYHGGKLDINGNSLTFHKLNGADDGAILTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 79 80 ------------------------------------------------MIDFSS---ND---S-TGVATLV-SPQYVVSVKH---NGG--Y--QYVKFG-----------------YADDSSYALVDRNN---------------------HW-------RDFHTPRLNKIVTEVTPLDITNAGTAKGT---------YQNADRFPVFYRVGTGTQYVK-----------DTNGKITYLMG-------------AYSYKTGGI----VNTPAISD--WS---FVTN---TTNT----------------PLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSY----------AGVNGNT-NWYTIIPAGDVKNTMKQDADAPVNTKQGEG-DI-HW-----SYDEKTGLGSLTQGSTSWE----MHGNLG-----------------ATWPASLNSGK-------DLTFQGG--G----TVVLENTVNQGAGTLTFDDD--YIVKPVD--TQTWKGGGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKINGTGVNPGSLSVGDGTVILAQRADDNGLSQAFSSVSIVSGRPTLVLNDDKQINP----DNIKWGYHGGKLDINGNSLTFHKLNGADDGAILTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 80 81 SVVSSTTSYQTYRDFAENKGEFRPGAEDVPLYDKNGNPVMTL--NKAPMIDFSS---ND---S-TGVATLV-SPQYVVSVKH---NGG--Y--QYVKFG-----------------YADDSSYALVDRNN---------------------HW-------RDFHTPRLNKIVTEVTPLDITNAGTAKGT---------YQNADRFPVFYRVGTGTQYVK-----------DTNGKITYLMG-------------AYSYKTGGI----VNTPAISD--WS---FVTN---TTNT----------------PLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSY----------AGVNGNT-NWYTIIPAGDVKNTMKQDADAPVNTKQGEG-DI-HW-----SYDEKTGLGSLTQGSTSWE----MHGNLG-----------------ATWPASLNSGK-------DLTFQGG--G----TVVLENTVNQGAGTLTFDDD--YIVKPVD--TQTWKGGGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKINGTGVNPGSLSVGDGTVILAQRADDNGLSQAFSSVSIVSGRPTLVLNDDKQINP----DNIKWGYHGGKLDINGNSLTFHKLNGADDGAILTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 81 82 SVVGTSLPYQTYRDFAENKGVFQAGAENVPLYDKNGNPVTTL--NKAPMIDFSS---ND---S-TGVATLV-SPQYVVSVKH---NGG--Y--QYVKFG-----------------YADDSSYALVDRNN---------------------HW-------RDFHTPRLNKIVTEVTPLDITNAGTAKGT---------YQNADRFPVFYRVGTGTQYVK-----------DTNGKITYLMG-------------AYSYKTGGI----VNTPAISD--WS---FVTN---TTNT----------------PLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSY----------AGVNGNT-NWYTIIPAGDVKNTMKQDADAPVNTKQGEG-DI-HW-----SYDEKTGLGSLTQGSTSWE----MHGNLG-----------------ATWPASLNSGK-------DLTFQGG--G----TVVLENTVNQGAGTLTFNDD--YIVKPVD--TQTWKGGGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKINGTGVNPGSLSVGDGTVILAQRADDNGLSQAFSSVSIVSGRPTLVLNDDKQINP----DNIKWGYHGGKLDINGNSLTFHKLNGADDGAILTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 82 83 SVVGTSLPYQTYRDFAENKGEFRPGAENVPLYDKNGNPVTTL--NKAPMIDFSS---ND---S-TGVATLV-SPQYVVSVKH---NVG--Y--QYVKFG-----------------YADDSSYTLVDRNN---------------------HW-------RDFHTPRLNKIVTEVTPLDITNAGTANGT---------YQNADRFPVFYRVGTGTQYVK-----------DTNGKISYLMG-------------AYSYKTGGI----VNKPFISD--WS---FVTN---TTNT----------------PLSTYGTPGDSGSPLFAWDADQNKWVLLAVLNSY----------AGVNGNT-NWYTIIPAGDVKNTMKQDADAPVNTKQDEG-DI-HW-----SYDEKTGLGSLTQGSSSWA----MHGNLG-----------------ATWPASLNSGK-------DLTFQGG--G----TVVLENTINQGAGTLTFDDD--YIVKPVD--TQTWKGGGIIVNGEHLVDWQINGVTGDSLHKLGTGTLKISGTGVNPGSLSVGDGTVILAQRADDNGLSQAFSSVSIVSGRPTLVLSDDKQINP----DNIKWGYHGGKLDINGNGLTFHKLNGADDGAILTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 83 84 -----DIPYQTYRDFSENKGLFKPGAMDIPLYDKDGKVVATL--DKAPMIDFSS---NA---R-TGFATLA-FPQYIVSVKH---NTG--Y--KNVRFG-----------------YGDDTNYTLISRNN---------------------YQ----GG-LDFHLPRLNKIVTEVIPLDITNAGTANGT---------YQNQERFPVFYRVGTGTQYVM-----------DKDGNPVRIAG-------------GYAYKTGGI----VNPPFSSN--LR---FTTN---IDNS----------------PLTSWGMAGDSGSPLFAWDAQQNKWVVLAVLHAA---------DRKVTGRT-NWYTIVPVSYVDNIMKQDADAPVISQRNKG-DI-HW-----SYDETTGIGTLTQGASSWS----MHGNPG-----------------LTSPASLNSGK-------DLTFQGG--G----SVVLENTVDQGAGTLTFNDD--YSIKPLD--SQTWKGGGIIINGDSIVDWQVNGVQGDNLHKLGTGTLKVNGTGINPGGLNVGEGTVILAQRPDSNGNVQAFNNVSIVSGRPTVVLSDAKQVNP----DNVKWGYRGGKLDINGNNLTFHKLNGADEGAVLTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 84 85 -----DIPYQTYRDFSENKGLFKPGAMDIPLYDKSGKVVATL--DKAPMIDFSS---NA---R-TGFATLA-FPQYIVSVKH---NTG--Y--KNVRFG-----------------YGDDTNYTLVSRNN---------------------YQ----GG-LDFHLPRLNKIVTEVIPLDITNAGTANGT---------YQNQERFPVFYRVGTGTQYVM-----------NKDGNPVRIAG-------------GYAYKTGGI----VNPPFSSN--LR---FTTN---IDNS----------------PLTSWGMAGDSGSPLFAWDAQQNKWVVLAVLHAA---------DRKVTGRT-NWYTIVPVSYVDNIMKQDADAPVISQRNKG-DI-HW-----SYDETTGIGTLTQGASSWS----MHGNPG-----------------LTSPASLNSGK-------DLTFQGG--G----SVVLENTVDQGAGTLTFNDD--YSIKPLD--SQTWKGGGIIINGDSIVDWQVNGVQGDNLHKLGTGTLKVNGTGINPGGLNVGEGTVILAQRPDSNGNVQAFNNVSIVSGRPTVVLSDAKQVNP----DNVKWGYRGGKLDINGNNLTFHKLNGADEGAVLTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 85 86 -----DIPYQTYRDFSENKGLFKPGAMDIPLYDKDGKVVATL--DKAPMIDFSS---NA---R-TGFATLA-FPQYIVSVKH---NTG--Y--KNVRFG-----------------YGDDTNYTLISRNN---------------------YQ----GG-LDFHLPRLNKIVTEVIPLDITNAGTANGT---------YQNQERFPVFYRVGTGTQYVM-----------DKDGNPVRIAG-------------GYAYKTGGI----VNPPFSSN--LR---FTTN---IDNS----------------PLTSWGMAGDSGSPLFAWDAQQNKWVVLAVLHAA---------DRKVTGRT-NWYTIVPVSYVDNIMKQDADALVISQRNKG-DI-HW-----SYDETTGIGTLTQGASSWS----MHGNPG-----------------LTSPASLNSGK-------DLTFQGG--G----SVVLENTVDQGAGTLTFNDD--YSIKPLD--SQTWKGGGIIINGDSIVDWQVNGVQGDNLHKLGTGTLKVNGTGINPGGLNVGEGTVILAQRPDSNGNVQAFNNVSIVSGRPTVVLSDAKQVNP----DNVKWGYRGGKLDINGNNLTFHKLNGADEGAVLTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 86 87 -----DIPYQTYRDFSENKGLFKPGAMDIPLYDKSGKVVATL--DKAPMIDFSS---NA---R-TGFATLA-FPQYIVSVKH---NTG--Y--KNVRFG-----------------YGDDTNYTLISRNN---------------------YQ----GG-LDFHLPRLNKIVTEVIPLDITNAGTANGT---------YQNQERFPVFYRVGTGTQYVM-----------DKDGNPVRIAG-------------GYAYKTGGI----VNPPFSSN--LR---FTTN---IDNS----------------PLTSWGMAGDSGSPLFAWDAQQNKWVVLAVLHAA---------DRKVTGRT-NWYTIVPVSYVDNIMKQDADAPVISQRNKG-DI-HW-----SYDETTGIGTLTQGASSWS----MHGNPG-----------------LTSPASLNSGK-------DLTFQGG--G----SVVLENTVDQGAGTLTFNDD--YSITPLD--SQTWKGGGIIINGDSIVDWQVNGVQGDNLHKLGTGTLKVNGTGINPGGLNVGEGTVILAQRPDSNGNVQAFNNVSIVSGRPTVVLSDAKQVNP----DNVKWGYRGGKLDINGNNLTFHKLNGADEGAVLTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 87 88 --VGMDIPYQTYRDFAENKGAFSVGALDIPLYKKDGTLYSTL--NKAPMIDFSA---VD---SGQTVATLI-SPQYIVSVKH---NTG--Y--KNVRFG-----------------YRDDSSYILVDRNN---------------------SS-------VDFHTPRLNKIVTEVVPADITDAGTANGT---------YQNQDRFPIFYRVGTGTQYVK-----------DRNGKLTQLAG-------------GYAYRTGGT----VGKPTSSN--KR---IVSN---PGNTYS----------AANGPMPSYGIPGDSGSPLFAWDTQRNKWVLVAVLNSY----------AGNAGKT-NWFTVIPVNEVSANIEADTDAPVTPTSTTE-NI-NW-----TYDISTGTGKLTQGTDAWE----MHGRDT-----------------GSSAVSFNHGK-------DLSFENT--G----TVVLKDIVNQGAGTLTFNGD--YIVKPDA--DQTWVGGGIIVNGDHTVNWQVNGVKGDSMHKLGTGTLNISGTGINPGTLSVGDGTVVLAQKPDSNGQVQAFESASIVSGRPTLVLSDSQQMNP----DNIKWGYRGGKLDINGNDLTFHALNAADEGAILTNSG-SLATTSLDFNSTDTTKPVTT---------------------------------------------------------------------------------------------MFHGFFTGNVNVKNNATSNVNNTFVVDGGINTPAGSMTQQGGRLFFQGHPVIHAVSTQSVANKLKALGDDSVLTQPVSFTQSDWQTRQFNLKSLDLNNAAFYLARN-AGLITTINANN-STVTLGSEDLYIDTNDGNGVKTTPVEGQSVATASEDQSHFTGNVNLTNGSAL------ 88 89 SVVNNLLPYQIYRDFAENKGDFIPGTESLELYNNSGLLVTTL--NKAPMPDFSS---VD---RLLGVATLV-NPQYVVSVKH---NGG--Y--SRVRFG--------------------TSNYTLVDRNN---------------------YS----A--RDFHTPRLNKLVTDVVPVEVTSAGTAQGT---------YKNVTKFPVFYRIGTGTQIYK-----------NEQGYYT-LNG-------------AYSYLTGGI----VPTPSISD--WS---FVTN---AG----------------NGALASYGTPGDSGSPLLGWDTTLNKWALVGVLRAY----------AGTTGST-NWYVVIPTVQITANINADTDKPVTSEAGSG-DI-LW-----TFNSVTGTGQLVQGDNSWD----MHGQKD-----------------L----DLNYGK-------NLTFSGG--G----TIVLENSVTQGAGALTFNDD--YVVKPLD--DQTWIG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 89 90 SVVNNLLPYQIYRDFAENKGDFIPGTESLELYNNSGLLVTTL--NKAPMPDFSS---VD---RLLGVATLV-NPQYVVSVKH---NGG--Y--SRVRFG--------------------TSNYTLVDRNN---------------------YS----A--RDFHTPRLNKLVTDVVPVEVTSAGTAQGT---------YKNVTKFPVFYRIGTGTQIYK-----------NEQGYYT-LNG-------------AYSYLTGGI----VPTPSISD--WS---FVTN---AG----------------NGALASYGTPGDSGSPLLGWDTTLNKWALVGVLRAY----------AGTTGST-NWYVVIPTVQITANINADTDKPVTSEAGSG-DI-LW-----TFNSVTGTGQLVQGDNSWD----MHGQKD-----------------L----DLNYGK-------NLTFSGG--G----TIVLENSVTQGAGALTFNDD--YVVKPLD--DQTWIGGGVIVNDGHVVDWQVNGVSGDALHKLGTGTLKIDGSGINGGSLNTGDGAVILAQRPDGEGKVQAFSRVSLVSGRSIVILSDENQINP----DNIYWGYRGGTLDINGNDLTFHKLNAFDDGAIITSNG-RLARLTLSLNEKT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 90 91 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGKNGAVSGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGGKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAD-------------AYVWRTGGT----VGSPVISD--WS---LVSN---PGNLYQ----------GVNGPLASYGTSGDSGSPLFAWDAVKKQWVFVAVLHGY----------AGENGKT-NWFTVIPAGDVNNTIKQDSSGTVVPAVAGG-DI-VW-----NYSKGSGEGTLSQDGKVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNGD--YTVR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 91 92 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGKNGAVSGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGVKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAD-------------AYVWRTGGT----VGSPVISD--WS---LVSN---PGNLYQ----------GVNGPLASYGTSGDSGSPLFAWDAVKKQWVFVAVLHGY----------AGENGKT-NWFTVIPAGDVNNTIKQDSSGTVVPAVAGG-DI-VW-----NYSKGSGEGTLSQDGKVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNGD--YTVRPEG--NQTWVGGGIIVNDGHRVDWMVNGLAGDALHKIGKGTLVVAGSGENPGTLNTGDGTVILAQKADAAGRVRAFSEVSIVSGRPVVVLQDSHQIEG----DRIRWGYRGGTLDINGNDMAFNRLAAADEGAVLTS-------R--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 92 93 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGKNGAVSGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGVKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAD-------------AYVWRTGGT----VGSPVISD--WS---LVSN---PGNLYQ----------GVNGPLASYGTSGDSGSPLFAWDAVKKQWVFVAVLHGY----------AGENGKT-NWFTVIPAGDVNNTIKQDNSGTVVPAVAGG-DI-VW-----KYSKGSGEGTLSQGGQVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNGD--YTVRPEG--NQTWVGGGIIVNDGHRVDWMVNGLAGDALHKIGKGILVVAGSGENPGALNTGDGTVILAQKADAAGKVRAFSEVSIVSGRPVVVLQDSHQIEG----DRIRWGYRGGTLDINGNDMAFNRLAAADEGAVLTS-------RERPATVRL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 93 94 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGKNGAVSGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGVKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAD-------------AYVWRTGGT----VGSPVISD--WS---LVSN---PGNLYQ----------GVNGPLASYGTSGDSGSPLFAWDAVKKQWVFVAVLHGY----------AGENGKT-NWFTVIPAGDVNNTIKQDNSGTVVPAVAGG-DI-VW-----KYSQGSGEGTLSQSGQVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNGD--YTVRPEG--NQTWVGGGIIVNDGHRVDWMVNGLAGDALHKIGKGILVVAGSGENPGALNTGDGTVILAQKADAAGRVRAFSEVSIVSGRPVVVLQDSHQIEG----DRIRWGYRGGTLDINGNDMAFNRLAAADEGAVLTS-------R--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 94 95 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGKNGAVSGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGVKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAD-------------AYVWRTGGT----VGSPVISD--WS---LVSN---PGNLYQ----------GVNGPLASYGTSGDSGSPLFAWDAVKKQWVFVAVLHGY----------AGENGKT-NWFTVIPAGDVNNTIKQDNSGTVVPAVAGG-DI-VW-----KYSQGSGEGTLSQGGQVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNSD--YMVRPEG--NQTWVGGGIIVNDGHRVDWMVNGLAGDALHKIGKGILVVAGSGENPGALNTGDGTVILAQKADAAGRVRAFSEVSIVSGRPVVVLQDSHQIEG----DRIRWGYRGGTLDINGNDMAFNRLAAADEGAVLTS-------R--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 95 96 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGKNGAVGGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGVKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAG-------------AYAWKTGGT----VGSPVISD--WS---LVSN---PGYLYQ----------SVNGPLASYGTPGDSGSPLFAWDAVKKQWVLVAVLNGY----------AGEKGKT-NWFTVIPAGDVNNTIKQDSSGTVMPAVAGG-DI-VW-----NYSKGSGEGTLSQDGKVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNGD--YTVRPEG--NQTWVGGGIIVNDGHRVDWMVNGLAGDALHKTGKGTLVVAGSGENPGTLNTGDGTVILAQKADAAGRVRAFSEVRIVSGRPVVVLQDSHQIEG----DRIRWGYRGGTLDINGNDMTFHRLAAADEGAVLTS-------R--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 96 97 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGRNGAVGGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGVKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAG-------------AYAWKTGGT----VGSPLISD--WS---LVSN---PGYLYQ----------SVNGPLASYGTPGDSGSPLFAWDAVKKQWVLVAVLNGY----------AGEKGKT-NWFTVIPAGDVNNTIKQDSSGTVVPAVAGG-DI-VW-----NYSKGSGEGTLSQDGKVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNGD--YTVRPEG--NQTWVGGGIIVNDGHRVDWMVNGLAGDALHKTGKGTLVVAGSGENPGTLNTGDGTVILAQKADAAGRVRAFSEVRIVSGRPVVVLQDSHQIEG----DRIRWGYRGGTLDINGNDMTFHRLAAADEGAVLTS-------RAGSATVRLDFSPSGQ---------------------------------------------------------------------------------------------KAVMWHGHFTGNLSVLNNTSSAVDFIMDGGADMSGSFTQQGGGLYIQGHPVVHAVSSEAVAAALRKQGDNSVLTRPVSFTQKDWESRTFSIGQLKLKEASFSLSRN-ATLTGDIDADN-ATMVLGSDSLYLDMKDGTGSSSAPVKGTSAAGGASGTSTFRGNVNMRHSSLTV----- 97 98 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGRNGAVGGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGVKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAG-------------AYAWKTGGT----VGSPLISD--WS---LVSN---PGYLYQ----------SVNGPLASYGTPGDSGSPLFAWDAVKKQWVLVAVLNGY----------AGEKGKT-NWFTVIPAGDVNNTIKQDSSGTVVPAVAGG-DI-VW-----NYNKGSGEGTLSQDGKVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNGD--YTVRPEG--NQTWVGGGIIVNDGHRVDWMVNGLAGDALHKTGKGTLVVAGSGENPGTLNTGDGTVILAQKADAAGRVRAFSEVRIVSGRPVVVLQDSHQIEG----DRIRWGYRGGTLDINGNDMTFHRLAAADEGAVLTS-------R--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 98 99 SVVGNTLPWQTYRDFAENKGAFHAGATNIPLYGRNGAVGGRL--DKAPMMDFSV---VD---QILGVATLI-SPQYVAGVKH---NGS--Y--NTVRFG-----------------YADDTTYRLVDRNE---------------------HW-------RDFHTPRLNKLVTEVAPVSVTDAGTGKGV---------YQNRSRYPVFYRMGSGTQYTG-----------AASGALTRIAG-------------AYAWKTGGT----VGSPLISD--WS---LVSN---PGYLYQ----------SVNGPLASYGTPGDSGSPLFAWDAVKKQWVLVAVLNGY----------AGEKGKT-NWFTVIPAGDVNNTIKQDSSGTVVPAVAGG-DI-VW-----NYNKGSGEGTLSQDGKVWK----MNGFRG-----------------G----SLNDGK-------DITFGGK--G----TVVLKDDVVQGAGSLTFNGD--YTVRPEG--NQTWVGGGIIVNDGHRVDWMVNGLAGDALHKTGKGTLVVAGSGENPGTLNTGDGTVILAQKADAAGRVRAFSEVRIVSGRPVVVLQDSHQIEG----DRIRWGYRGGTLDINGNDMTFHRLAAADEGAVLTS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 99 100 -----------------------------------------L--DKAPMADFSS---VS---S-NGVATLV-SPQYIVSVKH---NGG--Y--QSVSFG-----------------NGKN-TYSLVDRNN---------------------HS----S--VDFHAPRLNKLVTEVIPSAITSEGTKANA---------YKDTERYTAFYRVGSGTQYTK-----------DKDGNLVKVAG-------------GYAFKTGGT----TGVPLISD--AT---IVSN---PGQTYN----------PVNGPLPDYGAPGDSGSPLFAYDEQQKKWVIVAVLRAY----------AGINGAT-NWWNVIPTDYLNQVMQDDFDAPVDFVSGLP-PL-NW-----TYDKTSGTGTLSQGSKNWT----MHGQKD-----------------N----DLNAGK-------NLVFSGQ-NG----AIVLKDSVTQGAGYLEFKDS--YTVSAES--GKTWTGAGIITDKGTNVTWKVNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGTVVLNQQADTAGNVQAFSSVNLASGRPTVVLGDARQVNP----DNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITNNA-QQKSRLLLDLKAQDTNVSVP-IGSISP----FG-----------GTGTPGNLYSMILNGQTRFYILKSASYGNTLWGNSLNDPAQWEFVGTDKNKAVQTVKDRILAGRAKQPVIFHGQLTGNMDVTIPQLPGGRKV-ILDGSVNLPEGTLSEDSGTLIFQGHPVIHASVSGSA---------------PVSLNQKDWENRQFIMKTLSLKDADFHLSRN-ASLNSDIKSDN-SHITLGSDRVFVDKNDGTGNYVILEEG------------------------------- 100 101 -IVRSDIAYQIYRDFAENKGLFVPGANDIPVYDKDGKLVGRL--GKAPMADFSS---VS---S-NGVATLV-SPQYIVSVKH---NGG--Y--RSVSFG-----------------NGKN-TYSLVDRNN---------------------HP----S--IDFHAPRLNKLVTEVIPSAVTSEGTKANA---------YKYTERYTAFYRVGSGTQYTK-----------DKDGNLVKVAG-------------GYAFKTGGT----TGVPLISD--AT---IVSN---PGQTYN----------PVNGPLPDYGAPGDSGSPLFAYDKQQKKWVIVAVLRAY----------AGINGAT-NWWNVIPTDYLNQVMQDDFDAPVDFVSGLG-PL-NW-----TYDKTSGTGTLSQGSKNWT----MHGQKD-----------------N----DLNAGK-------NLVFSGQ-NG----AIILKDSVTQGAGYLEFKDS--YTVSAES--GKTWTGAGIITDKGTNVTWKVNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGIVVLNQQADTAGNIQAFSSVNLASGRPTVVLGDARQVNP----DNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITNNA-QQKSQLLLDLKAQDTNVSEPTIGNISP----FG-----------GTGTPGNLYSMILNSQTRFYILKSASYGNTLWGNSLNDPAQWEFVGMNKNKAVQTVKDRILAGRAKQPVIFHGQLTGNMDVAIPQVPGGRKV-IFDGSVNLPEGTLSQDSGTLIFQGHPVIHASISGSA---------------PVSLNQKDWENRQFTMKTLSLKDADFHLSRN-ASLNSDIKSDN-SHITLG---------------------------------------------------- 101 102 GIVRSDIAYQIYRDFAENKGLFVPGANDIPVYDKDGKLVGRL--GKAPMADFSS---VS---S-NGVATLV-SPQYIVSVKH---NGG--Y--RSVSFG-----------------NGKN-TYSLVDRNN---------------------HP----S--IDFHAPRLNKLVTEVIPSAVTSEGTKANA---------YKYTERYTAFYRVGSGTQYTK-----------DKDGNLVKVAG-------------GYAFKTGGT----TGVPLISD--AT---IVSN---PGQTYN----------PVNGPLPDYGAPGDSGSPLFAYDKQQKKWVIVAVLRAY----------AGINGAT-NWWNVIPTDYLNQVMQDDFDAPVDFVSGLG-PL-NW-----TYDKTSGTGTLSQGSKNWT----MHGQKD-----------------N----DLNAGK-------NLVFSGQ-NG----AIILKDSVTQGAGYLEFKDS--YTVSAES--GKTWTGAGIITDKGTNVTWKVNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGIVVLNQQADTAGNIQAFSSVNLASGRPTVVLGDARQVNP----DNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITNNA-QQKSQLLLDLKAQDTNVSEPTIGNISP----FG-----------GTGTPGNLYSMILNSQTRFYILKSASYGNTLWGNSLNDPAQWEFVGMNKNKAVQTVKDRILAGRAKQPVIFHGQLTGNMDVAIPQVPGGRKV-IFDGSVNLPEGTLSQDSGTLIFQGHPVIHASISGSA---------------PVSLNQKDWENRQFTMKTLSLKDADFHLSRN-ASLNSDIKSDN-SHITLGSDRAFVDKNDGTGNYVIPEEGTSVPDTVNDRSQYEGNITLNHNSALDIG--- 102 103 GIVRSDIAYQIYRDFAENKGLFVPGANDIPVYDKDGKLVGRL--GKAPMADFSS---VS---S-NGVATLV-SPQYIVSVKH---NGG--Y--RSVSFG-----------------NGKN-TYSLVDRNN---------------------HP----S--IDFHAPRLNKLVTEVIPSAVTSEGTKANA---------YKYTERYTAFYRVGSGTQYTK-----------DKDGNLVKVAG-------------GYAFKTGGT----TGVPLISD--AT---IVSN---PGQTYN----------PVNGPLPDYGAPGDSGSPLFAYDKQQKKWVIVAVLRAY----------AGINGAT-NWWNVIPTDYLNQVMQDDFDAPVDFVSGLG-PL-NW-----TYDKTSGTGTLSQGSKNWT----MHGQKD-----------------N----DLNAGK-------NLVFSGQ-NG----AIILKDSVTQGAGYLEFKDS--YTVSAES--GKTWTGAGIITDKGTNVTWKVNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGIVVLNQQADTAGNIQAFSSVNLASGRPTVVLGDARQVNP----DNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITNNA-QQKSQLLLDLKAQDTNVSEPTIGNISP----FG-----------GTGTPGNLYSMILNSQTRFYILKSASYGNTLWGNSLNDPAQWEFVGMNKNKAVQTVKDRILAGRAKQPVIFHGQLTGNMDVAIPQVPGGRKV-IFDGSVNLPEGTLSQDSGTLIFQGHPVIHASISGSA---------------PVSLNQKDWENRQFTMKTLSLKDADFHLSRN-ASLNSDIKSDN-SHITLGSDRAFVDKNDGTGNYVIPEEGTSVPDTVNDRSQYEGNITLNHNSALDIG--- 103 104 -IVRSDISYQIYRDFAENKGLFVPGATDIPVYDKNGKLVGRL--DKAPVTDFSS---VS---S-NGVATLV-SPQYIVSVKH---NGG--Y--QSVGFG-----------------NGKN-SYSLVDRNN---------------------HP----Y--VDFHAPRLNKLVTEVIPSAVTDEGTKSNA---------YKNTERYTAFYRIGSGTQYTK-----------DKDGKLTSIAG-------------GYAFKTGGT----IGIPLISN--TT---IVSN---PGQTYN----------PVNGPLPNYGAPGDSGSPLFAYDALQKKWVIVAVLRAY----------AGPNGAT-NWWDVIPTDYLNQVMLEDFDSPVNLASEQG-PL-NW-----TYDKTSGTGTLSQGNKNWV----MHGQKG-----------------N----DLNAGK-------NLVFSGD-NG----VIVLKDSVTQGAGYLEFKDS--YTVSAES--GKTWTGAGIITDKGAEVTWKVNGVAGDNLHKLGEGTLVMNGSGVNPGGLKTGDGTVVLNQQEDAAGNVQAFSSVNLASGRPTVVLGDARQVNP----DNISWGYRGGTLDLNGNAVTFSRLLAADYGAVITNNA-QQKSRLLLELKAMDTDVSVP-VGNISP----FG-----------GSGTPGNLYSMTLNNQTRFYILKSSTYGNTLWGNSLNDPKQWEFVGTDKNKAIQTVKDRILAERAKQPVIFHGQLTGNMDVTIPQLPGGRKV-IFDGSVNLPEGTLNQDSGTLVFQGHPVIHASVNGSA---------------PVSVTQKDWENRGFTLKTLSLKNADFHLSRN-ATLNGDIQADN-SHIALG---------------------------------------------------- 104 105 -IVRSDISYQIYRDFAENKGLFVPGATDIPVYDKNGKLVGRL--DKAPVTDFSS---VS---S-NGVATLV-SPQYIVSVKH---NGG--Y--QSVGFG-----------------NGKN-SYSLVDRNN---------------------HP----Y--VDFHAPRLNKLVTEVIPSAVTDEGTKSNA---------YKNTERYTAFYRIGSGTQYTK-----------DKDGKLTSIAG-------------GYAFKTGGT----IGIPLISN--TT---IVSN---PGQTYN----------PVNGPLPNYGAPGDSGSPLFAYDALQK----------------------------------------------------------------------------------------------------------------------------------------------NG----LLLL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 105 106 -IVRSDIPYQLFRDFAENKGLFVPGAKDIPVYDKDGKLVGRL--DKVPFADFSS---AS---T-SGFATLV-SPQYIVSVKH---NGG--Y--QSVSFG-----------------NGKN-TYSLVDRNN---------------------HP----S--ADFHVPRLNKLVTEVAPVSVTAEGTKRDA---------YKNTERYTAFYRVGSGTQYTK-----------DKDGNLINIAG-------------GYAFKTGGT----AGVPQISD--AT---IVSA---PGETYN----------PANGLLPNYGMPGDSGSPLFAYDALQKKWVIVAVLGAN----------RGLHGTG-NLWNVIRTDFLSQVMQEDFDSPVKLTSGQG-PL-NW-----TYDTTSGTGTLSQGSQSWA----MHGQKG-----------------N----DLNAGK-------NLVFSGQ-NG----AILLKDSVTQGAGYLEFKDS--YTVSADA--GKTWTGAGIITDKGADVTWKVNGVAGDNLHKLGEGTLTINGIGVNPGGLKTGDGTVVLNQQADAAGNVQAFSSVNLASGRPTVVLGDARQVNP----DNISWGYRGGTLDLNGNTVTFTRLLATDYGAVITNNA-QQKSQLLLDLKALDTNVSSPSIGKISP----FG-----------GSGTPGNLYSTTINNQTRFYILKSASYGNTLWGNSLNDPKQWEFVGTDKNKAIQIIKDRILAERAKQPVIYHGQLTGNMDVTIPPLPGGRKA-IFDGSVNIPEGTLSQDGGTLVFQGHPVIHASVNGSA---------------PVSLTQKDWENREFTLKTLSLKNADFHLSRN-AALNGDIQSDN-SHIALG---------------------------------------------------- 106 107 --VSAEIPYQTFRDFAENKGVFTPGVTGIEINDNNGNKVGVL--D-VPMLDFSS---LS---R-DGHTTLI-HPGYVVSAKH---SGLQSV--SSATFG-----------------YDQ--IYKIV-DNN---------------------LA----G--IDFSAPRLNKLVTEVIPADI----QGKDK---------FNNN-RYTAFYRAGVGSQYIR-----------YANGTDKLLQAYTP----------DKAYLTGGT----VGKPYYTHYNGMKM-ISAN---PGNTFD----------KNQGPLASYGQIGDSGSPLYAWDNIDKKWVLTGVTLHN----------YGVKGAR-NDWLLIPHDFISQKLQDDLKPIIV--ASPEENILRW-----EFDRSRGTGTLSQGEKIFS----MTGSVN-----------------G----NANTGN-------NLVFSGN-EG----KIELVSSVEQGAGYLQFDKD--YTVLTNN--NSTWTGAGIIVGDEANVKWGVNGIAGDYLHKVGSGTLTVNGHGENKGGLKVGDGVVVLEQQPDANQKQQAFSHINIASGRATVKLNGANQVDA----DNISWGYRGGKLDLNGYDFTFSRLQAADYGAEISNDNQTDKSIVTLSLSPLKAEEINVVVNNINI----MG-----------GTGKPGDLYYTT--FDGNYYLLKSNRYGSALFGALNNQSEWQRLGKNKEKAIGLYTQMKMQESD-LLSYIYHGKITGNTSVEIPKLAG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 107 108 --VSAEIPYQTFRDFAENKGVFTPGVTGIEINDNNGNKVGVL--D-VPMLDFSS---LS---R-DGHTTLI-HPGYVVSAKH---SGLQSV--SSATFG-----------------YDQ--IYKIV-DNN---------------------LA----G--IDFSAPRLNKLVTEVIPADI----QGKDK---------FNNN-RYTAFYRAGVGSQYIR-----------YANGTDKLLQAYTP----------DKAYLTGGT----VGKPYYTHYNGMKM-ISAN---PGNTFD----------KNQGPLASYGQIGDSGSPLYAWDNIDKKWVLTGVTLHN----------YGVKGAR-NDWLLIPHDFISQKLQDDLKPIIV--ASPEENILRW-----EFDRSRGTGTLSQGEKIFS----MTGSVN-----------------G----NANTGN-------NLVFSGN-EG----KIELVSSVEQGAGYLQFDKD--YTVLTNN--NSTWTGAGIIVGDEANVKWGVNGIAGDYLHKVGSGTLTVNGHGENKGGLKVGDGVVVLEQQPDANQKQQAFSHINIASGRATVKLNGANQVDA----DNISWGYRGGKLDLNGYDFTFSRLQAADYGAEISNDNQTDKSIVTLSLSPLKAEEINVVVNNINI----MG-----------GTGKPGDLYYTT--FDGNYYLLKSNRYGSALFGALNNQSEWQRLGKNKEKAIGLYTQMKMQESD-LLSYIYHGKITGNTSVEIPKLAG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 108 109 --VSAEIPYQTFRDFAENKGVFTPGVTGIEINDNNGNKVGVL--D-VPMLDFSS---LS---R-DGHTTLI-HPGYVVSAKH---SGLQSV--SSATFG-----------------YDQ--IYKIV-DNN---------------------LA----G--IDFSAPRLNKLVTEVIPADI----QGKDK---------FNNN-RYTAFYRAGVGSQYIR-----------YANGTDKLLQAYTP----------DKAYLTGGT----VGKPYYTHYNGMKM-ISAN---PGNTFD----------KNQGPLASYGQIGDSGSPLYAWDDIDKKWVLTGVTLHN----------YGVKGAR-NDWLLIPHDFISQKLQDDLKPIIV--ASPEENILRW-----EFDRSRGTGTLSQGEKIFS----MTGSVN-----------------G----NANTGN-------NLVFSGN-EG----KIELVSSVEQGAGYLQFDKD--YTVLTNN--NSTWTGAGIIVGDEANVKWGVNGIAGDYLHKVGSGTLTVNGHGENKGGLKVGDGVVVLEQQPDANQKQQAFSHINIASGRATVKLNGANQVDA----DNISWGYRGGKLDLNGYDFTFSRLQAADYGAEISNDNQTDKSIVTLSLSPLKAEEINVVVNNINI----MG-----------GTGKPGDLYYTT--FDGNYYLLKSNRYGSALFGALNNQSEWQRLGKNKEKAIGLYTQMKMQESD-LLSYIYHGKITGNTSVEIPKLAG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 109 110 --VSAEIPYQTFRDFAENKGVFTPGVTGIEINDNNGNKVGVL--D-VPMLDFSS---LS---R-DGHTTLI-HPGYVVSAKH---GGLQSV--SSATFG-----------------YDQ--IYKIV-DNN---------------------LA----G--IDFSAPRLNKLVTEVIPADI----QGKDK---------FNNN-RYTAFYRAGVGSQYIR-----------YANGTDKLLQAYTP----------EKAYLTGGT----VGKPYYTHYNGMKM-ISAN---PGNTFD----------KNQGPLASYGQSGDSGSPLYAWDNIDKKWVLAGVTLHN----------YGVKGAR-NDWLLIPHDFISQKLQDDLKPIIV--ASPEENILRW-----EFDRSRGTGTLSQGEKIFS----MTGSVN-----------------G----NANTGN-------NLVFSGN-EG----KIELVSSVEQGAGYLQFDKD--YTVLTNN--NSTWTGAGIIVGDEANVKWGVNGIAGDNLHKVGSGTLTVNGHGENKGGLKVGDGVVVLEQQPDANQKQQAFSHINIASGRATVKLNGANQVDA----DNISWGYRGGKLDLNGYDFTFSRLQAADYGAEISNDNQTDKSIVTLSLSPL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 110 111 STVSAEIPYQTFRDFAENKGVFTPGVTGIEINDNNGNKVGVL--D-VPMLDFSS---LS---R-DGHTTLI-HPGYVVSAKH---GGLQSV--SSATFG-----------------YDQ--IYKIV-DNN---------------------LA----G--IDFSAPRLNKLVTEVIPADI----QGKDK---------FNNN-RYTAFYRAGVGSQYIR-----------YANGTDKLLQAYTP----------EKAYLTGGT----VGKPYYTHYNGMKM-ISAN---PGNTFD----------KNQGPLASYGQSGDSGSPLYAWDNIDKKWVLAGVTLHN----------YGVKGAR-NDWLLIPHDFISQKLQDDLKPIIV--ASPEENILRW-----EFDRSRGTGTLSQGEKIFS----MTGSVN-----------------G----NANTGN-------NLVFSGN-EG----KIELVSSVEQGAGYLQFDKD--YTVLTNN--NSTWTGAGIIVGDEANVKWGVNGIAGDNLHKVGSGTLTVNGHGENKGGLKVGDGVVVLEQQPDANQKQQAFSHINIASGRATVKLNGANQVDA----DNISWGYRGGKLDLNGYDFTFSRLQAADYGAEISNDNQTDKSIVTLSLSPLKAEEINVVVNNINI----MG-----------GTGKPGDLYYTT--FDGNYYLLKSNRYGSALFGALNNQSEWQRLGKDKEKAIGLYTQMKMQESA-PLSYIYHGKITGNTSVEIPKLAG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTGNDVISVEGKSAAAGTSSYTGHITLEQKSALDIRDN---- 111 112 --VSAEIPYQTFRDFAENKGVFTPGVTGIEINDNNGNKVGVL--D-VPMLDFSS---LS---R-DGHTTLI-HPGYVVSAKH---GGLQSV--SSATFG-----------------YDQ--IYKIV-DNN---------------------LA----G--IDFSAPRLNKLVTEVIPADI----QGKDK---------FNNN-RYTAFYRAGVGSQYIR-----------YANGTDKLLQAYTP----------EKAYLTGGT----VGKPYYTHYNGMKM-ISAN---PGNTFD----------KNQGPLASYGQSGDSGSPLYAWDNIDKKWVLAGVTLHN----------YGVKGAR-NDWLLIPHDFISQKLQDDLKPIIV--ASPEENILRW-----EFDRSRGTGTLSQGEKIFS----MTGSVN-----------------G----NANTGN-------NLVFSGN-EG----KIELVSSVEQGAGYLQFDKD--YTVLTNN--NSTWTGAGIIVGDEANVKWGVNGIAGDNLHKVGSGTLTVNGHGENKGGLKVGDGVVVLEQQPDANQKQQAFSHINIASGRATVKLNGANQVDA----DNISWGYRGGKLDLNGYDFTFSRLQAADYGAEISNDNQTDKSIVTLSLSPLKAEEINVVVNNINI----MG-----------GTGKPGDLYYTT--FDGNYYLLKSNRYGSALFGALNNQSEWQRLGKDKEKAIGLYTQMKMQESA-PLSYIYHGKITGNTSVEIPKLAG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNVDFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 112 113 --VSAEIPYQTFRDFAENKGVFTPGVTGIEIKDNNGNKVGVL--N-APMLDFSS---LS---R-DGHTTLI-HPGYVVSAKH---GGLQSV--SSATFG-----------------YNQ--IYKIV-DNN---------------------LA----G--MDFSVPRLNKLVTEVIPADI----QGKDK---------FNNN-RYTAFYRAGVGSQYIR-----------YANGTDKLLQAYTP----------EKAYLTGGT----VGKPYYTHYNGMKM-ISAN---PGNTFD----------KNQGPLASYGQNGDSGSPLYAWDNIDKKWVLAGVTLHN----------YGVKGAR-NDWLLMPHDFISQKLQDDLKPIIV--ASPEESILRW-----EFDRSRGTGTLSQGEKIFS----MTGSVN-----------------G----NANTGN-------NLVFSGN-EG----KIELVSSVEQGAGYLQFDKD--YTVLTNN--NSTWTGAGIIVGDEANVKWGVNGIAGDNLHKVGSGTLTVNGHGENKGGLKVGDGAVVLEQQPDANQKQQAFSHINIASGRATVKLNGANQVDA----DNISWGYRGGILDLNGYDFTFSRLQAADYGAEISNDNQTDKSIVTLSLSPLKAEEIKVVVNNINI----MG-----------GTGKPGDLYYTT--FDGNYYLLKSNRYGSALFGALNNQSEWQRLGKDKEKAIGLYAQMKMQESA-PLSYIYHGKITGNTSVEIPKLAG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPLIHA--------------------------------------------------------------------------------------------------------------------------- 113 114 ------------------------------------------------MLDFSS---LS---R-DGHTTLI-HPGYVVSAKH---GGLQSV--SSATFG-----------------YNQ--IYKIV-DNN---------------------LA----G--MDFSVPRLNKLVTEVIPADI----QGKDK---------FNNN-RYTAFYRAGVGSQYIR-----------YANGTDKLLQAYTP----------EKAYLTGGT----VGKPYYTHYNGMKM-ISAN---PGNTFD----------KNQGPLASYGQNGDSGSPLYAWDNIDKKWVLAGVTLHN----------YGVKGAR-NDWLLMPHDFISQKLQDDLKPIIV--ASPEESILRW-----EFDRSRGTGTLSQGEKIFS----MTGSVN-----------------G----NANTGN-------NLVFSGN-EG----KIELVSSVEQGAGYLQFDKD--YTVLTNN--NSTWTGAGIIVGDEANVKWGVNGIAGDNLHKVGSGTLTVNGHGENKGGLKVGDGVVVLEQQPDANQKQQAFSHINIASGRATVKLNGANQVDA----DNISWGYRGGILDLNGYDFTFSRLQAADYGAEISNDNQTDKSIVTLSLSPLKAEEIKVVVNNINI----MG-----------GTGKPGDLYYTT--FDGNYYLLKSNRYGSALFGALNNQSEWQRLGKDKEKAIGLYAQMKMQESA-PLSYIYHGKITGNTSVEIPKLAG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 114 115 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 115 116 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDFKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KAKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAIINSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTTFYGPTQYYLLKKPKFGSVLMGSLKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENRAFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 116 117 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNSGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KAKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAIINSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTTFYGPTQYYLLKKPKFGSVLMGSLKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 117 118 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KEKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAIINSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTNFYGPTQYYLLKKPKFGSVLMGALKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 118 119 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KEKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAIINSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTNFYGPTQYYLLKKPKFGSVLMGALKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 119 120 STVSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 120 121 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KAKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAIINSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTTFYGPTQYYLLKKPKFGSVLMGSLKNTSEWQFAGTDLNQAVDMAKNNK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 121 122 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KAKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAIINSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTTFYGPTQYYLLKKPKFGSVLMGSLKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 122 123 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KAKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAIINSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTTFYGPTQYYLLKKPKFGSVLMGSLKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 123 124 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KAKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAIINSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTTFYGPTQYYLLKKPKFGSVLMGSLKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 124 125 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 125 126 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTAFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KEKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGK----------------TQSS-PAYRLLIMGLQLL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 126 127 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTTFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 127 128 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTTFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KEKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAITNSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTNFYGPTQYYLLKKPKFGSVLMGALKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 128 129 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTTFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IIDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KEKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAITNSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTNFYGPTQYYLLKKPKFGSVLMGALKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 129 130 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTTFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IVDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KEKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAITNSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTNFYGPTQYYLLKKPKFGSVLMGALKNTSEWQFAGTDLNQAVDMAKNNK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 130 131 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTTFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IVDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KEKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAITNSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTNFYGPTQYYLLKKPKFGSVLMGALKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 131 132 --VSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNAVGTL--D-VPMIDFSS---VS---R-RGSLTLL-SQGYGVSAKH---GGLGDV--NNASFG-----------------YDKN-NYTVVKNNK---------------------HS----G--LDFSLHRFSKLITEAAPADI----NISGQ---------LSDSSQYTTFYRAGAGTQYIK-----------ERSGKQT----HIP----------GT-FLTGGT----VGTPWY---SGNNL-ISSS---PGDTYN----------KSQGPLASYGQMGDSGSPLFAYDSLSEKWSLAGVTLHN----------NGVNGQK-NNWLLLPEDYIKNIITADFDPIISFNKNSKEHM-SW-----TYDAAKGVGRIQQDDQQFV----MHGNLN-----------------G----NLNAGK-------NLYFTGE-NG----IVDLKDNVNQGAGYLQFADD--YTVTTSN--DSSWSGGGIIVNYGTTVKWGINGVSGDDLHKVGDGTLIINGTGKNEGGLKIGAGTVILEQ-KEKNNDSTAFSSINISGGNSRVKLSGDNQIIP----DNVSWGFRGGYLDINGKNTEFSRLQAVDYGAAITNSS-TDKSLLTLNLSPLKKDEIAVSVKALDMNAIFQG-----------GHGTAGDLYKTNFYGPTQYYLLKKPKFGSVLMGALKNTSEWQFAGTDLNQAVDMAKNNKLTSSA-QASYLYHGKLLGNMDIVIPELTG-NDILTLDGSVSI-SGDMSKQDGALIFQGHPVIHAGQT-------------------VSASQSDWENREFSLNNLNLNNADFSLSRN-AFMNGNIRAVNQSTVIIGGDTVFTDKNDGTG--------------------------------------- 132 133 STVSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNLTGVL--N-TPMLDFSS---LS---R-DGHTTLI-HPGYGVSAKH---GRLQSL--KTATFG-----------------YNA--EYKIV-NNN---------------------HA----S--YDFTAPRYSKLVTEVIPVNT----G-DGK---------YNDSKKYTAFYRAGVGDQYIK-----------DKKGNHTLLNRYAP----------QNAYLTGGT----VGTPYYGRVSNQTV-LISS---PGNTFN----------QTHGPLASYGQPGDSGSPLYAWDNIQNKWVLAGVTLYN----------EGVNGSR-NWWLELPKSFINETIKSDSKEIVV--KNKKEDI-TW-----SFDKTQGTGVINLERKDHI----INGHKN-----------------N----NPDYGD-------NIVFSGE-EG----VINIKNDIAQGAGFIQFNNN--YIVSTQN--NSTWTGSGIIVNDGSEVYWGINGVKDDNLHKLGSGKLIINGNGINTGGLKVGDGTVLLSQHKDAEGRVQAFSSVNISSGRPVVVLSDDKQINP----DNISWGYRGGTLDLNGNNITFTRIQASDYGAIITNNN-DKKSITNLNISTLKDTDINVSVSDVHV----LG-----------GKGKPGDLFYDR--GTGRYLILKKERY-SPFFQDVNNTSVWQYVGKNRNEAIAVVKNEKIKNSS-K-PYLFHGQLNGNMDINIQSGMG-VNTFAIDGSVNIPNGTLSNKLGSLIFQGHPVIHAGVG-------------------VSAEQNDWETRYFTLNTLNLDGSDFHLSRN-AVMTGNIHATNSSKVTLGSSSVYVDRNDGTGESVNSTSGTASD--------------------------- 133 134 STVSAEIPYQTFRDFAENKGVFTPGATGIEIKDKNGNLTGVL--N-TPMLDFSS---LS---R-DGHTTLI-HPGYGVSAKH---GRLQSL--KTATFG-----------------YNA--EYKIV-NNN---------------------HA----S--YDFTAPRYSKLVTEVIPVNT----G-DGK---------YNDSKKYTAFYRTGVGDQYIK-----------DKKGNHTLLNRYAP----------QNAYLTGGT----VGTPYYGRVSNQTV-LISS---PGNTFN----------QTHGPLASYGQSGDSGSPLYAWDNIQNKWVLAGVTLYN----------EGVNGSR-NWWLELPNSFINETIKSDSKEIVV--KNKKEDI-TW-----SFDKTQGTGVINLERKDHI----INGHKN-----------------N----NPDYGD-------NIVFSGE-EG----VINIKNDIAQGAGFIQFNNN--YIVSTQN--NSTWTGSGIIVNDGSEVYWGINGVKDDNLHKLGSGKLIINGNGINTGGLKVGDGTVLLSQHKDAEGRVQAFSSVNISSGRPVVVLSDDKQINP----DNISWGYRGGTLDLNGNNITFTRIQASDYGAIITNNN-DKKSITNLNISTLKDTDINVSVSDVHV----LG-----------GKGKPGDLFYDR--GTGRYLILKKEKY-SPFFQDVNNTSVWQYVGKNRNEAIAVVKSEKIKNSS-K-PYLFHGQLNGNMDINIQSGMG-VNTFAIDGSVNIPNGTLSNKLGSLIFQGHPVIHAGVG-------------------VSAEQNDWETRYFTLNTLNLDGSDFHLSRN-AVMTGNIHATNSSKVTLGSSSVYVDRNDGTGESVNSTSATASDINEKDLSKFTGDITADNSNII------ 134 135 STVSAEIPYQTFRDFAENKGVFTPGAIGIEIKDKNGNLTGVL--N-TPMIDFSS---LS---R-DGHTTLV-HPGYGVSAKH---GRLQSL--KTATFG-----------------YNT--EYKIV-NNN---------------------HA----P--YDFTAPRYNKLVTEVAPAIL----G-DGG---------YNNSKKYTTFYRAGVGEQYIK-----------EKNGTHTLLTKYDP----------TTAYLTGGT----VGQPYYGKANNQTV-LIST---PGNTFD----------KSQGPLASYGQPGDSGSPLYAWDKTQNRWVLAGVTLYN----------SGVNGHQ-NWWLDLPNSFINKTIKDDSKEIVV--KNKKEDI-TW-----SFDKTQGTGVINLERKDHI----INGHKN-----------------N----NPDYGD-------NIVFSGE-EG----VINIKNDIAQGAGFIQFNNN--YIVSTQN--NSTWTGSGIIVNDGSEVYWGINGVKDDNLHKLGSGKLIINGNGINTGGLKVGDGTVLLSQHKDAEGRVQAFSSVNISSGRPVVVLSDDKQINP----DNISWGYRGGTLDLNGNNITFTRIQASDYGAIITNNN-DKKSITNLNISTLKDTDINVSISDVHV----LG-----------GKGKPGDLFYDR--GTGRYLILKKERY-SPFFQDVNNTSVWQYVGKNRNEAIAVVKNEKIKNSS-N-PYLFHGQLNGNMDINIQSGMG-VNTFAIDGSVNIPNGTLSNKLGSLIFQGHPVIHAGVG-------------------VSAEQNDWETRYFTLNTLNLDGSDFHLSRN-AVMTGNIHATNSSKVTLGSSSVYIDRNDGTGESVNSTSGTASD--------------------------- 135 136 ATVSAEIPYQIFRDFAENKGQFTPGSTNISIYDKQGNLVGKL--DKAPMADFSSAT-IATGSLPPGDHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YTKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDVGAVSGA---------YQAGGRFTAFYRLGGGMQCVK-----------DKNGNLTQVYT-------------NGGFLTGGT----VSALSSYN--NGQM-ISAQ---TANIFN----------PANGPLANYLIMGDSGSPLFAYDSWQKKWVLIGVTSSK-------------TDSG-NNWVVTTQDFLGQQPQNDFDKTIAYTSGKG-AL-QW-----KYDAANGTGTLTQGNTSWD----MHGKKG-----------------N----DLNAGK-------NLLFTGN-NG----EVVLLNSVNQGAGYLQFAGD--YKVSALN--GQTWMGGGIITDKGTHVLWQVNGVAGDNLHKIGEGTLTVNGTGVNAGGLKVGDGTVILNQQADANGKVQAFSSVDIASGRPTVVLSDAQQVNP----DNISWGYRGGRLDLNGNNLTFTRLQAADYGAIITNNS-EKKSTVTLDLQTLKASDINVPVNTVNI----FG-----------GKGSPGDLYYDSSTGN--YYILKASS-YSPFFSDLNNSSVWQNVGKDRNKAIDTVKQQKIEASS--QPYMYHGQLNGNMDVNIPQLSG-KDILALDGSVNLPEGSITKKSGTLIFQGHPVIHAGMT-------------------TSASQSDWETRQFTLGKLKLDAATFYLSRN-GQMQGDINATNGSTVILG---------------------------------------------------- 136 137 ATVSAEIPYQIFRDFAENKGQFTPGSTNISIYDKQGNLVGKL--DKAPMADFSSAT-ITSGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDVGAVSGA---------YQAEGRFTAFYRLGGGQQFIK-----------DKNGNLTQIYT-------------SGGFLVGGT----VGALNSYS--NGEM-ITTP---SANIFN----------PSQGPLANYLIMGDSGSPLFAYDSWEKKWVLIGVTSSM-------------THSG-NNWVVTTRDFLSQQSQNDFDKTITYTSGKG-AL-QW-----KYDAANGSGTLTQENSSWD----MHGKKG-----------------N----DLNTGK-------NLLFTGN-NG----EVVLQNSVNQGAGYLQFAGN--YRVSALN--GQTWMGGGIITDKGTHVLWQVNGVASDNLHKTGEGTLTVNGTGVNAGGLKVGDGTVILSQQADADGKVQAFSSVDIASGRPTVVLSDAQQVNP----DNISWGYRGGRLDLNGNNLIFTRLQAADYGAIITNNS-EKKSTVTLDLQTLKASDINVPVNTINI----FG-----------GKGSPGDLYYDSSTGQ--YFILKASS-YSPFFSDLNNSSVWQNVGKDRNKAIDTVKQQKIETSS--QPYMYHGQLNGNMDVNIPQLSG-KDVLALDGSVNLPEGSITKKSGTLIFQGHPVIHAGTT-------------------TSASQSDWENRQFTLGKLKLDAATFHLSRN-GQMQGDINATNGSTVILGSDRVFTDRNDGTG--------------------------------------- 137 138 ATVSAEIPYQIFRDFAENKGQFTPGTTNISIYDKQGNLVGKL--DKAPMADFSSAT-ITTGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYE-NNWVVTTQDFLGQQPQNDFDKTIAYTSGEG-VL-QW-----K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 138 139 ATVSAEIPYQIFRDFAENKGQFTPGTTNISIYDKQGNLVGKL--DKAPMADFSSAT-ITTGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYG-NNWVVTTQGFLGQQPQNDFDKTIAYTSGEG-VL-QW-----K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 139 140 ATVSAEIPYQIFRDFAENKGQFTPGTTNISIYDKQGNLVGKL--DKAPMADFSSAT-ITTGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYG-NNWVVTTQDFLGQQPQNDFDKTIAYTSGEG-VL-QW-----KYDAANGTGTLTQGNTTWD----MHGKKG-----------------N----DLNAGK-------NLLFTGN-NG----EVVLQNSVNQGGGYLQFAGD--YRVSALN--GQTWMGGGIITDKGTHVLWQVNGVAGDNLHKTGEGTLTVNGTGVNAGGLKVGDGTVILNQQADADGKVQAFSSVGIASGRPTVVLSDSQQVNP----DNISWGYRGGRLELNGNNLTFTRLQAADYGAIITNNS-EKKSTVTLDLQTLKASDINVPVNTVSI----FG-----------GRGAPGDLYYDSSTKQ--YFILKASS-YSPFFSDLNNSSVWQNVGKDRNKAIDTVKQQKIEASS--QPYMYHGQLNGNMDVNIPQLSG-KDVLALDGSVNLPEGSITKKSGTLIFQGHPVIHAGTT-------------------TSSSQSDWETRQFTLEKLKLDAATFHLSRN-GKMQGDINATNGSTVILGSSRVFTDRSDGTGNAVSSVEGSATATTVGDQSDYSGNVTLENKSSL------ 140 141 ATVSAEIPYQIFRDFAENKGQFTPGTTNISIYDKQGNLVGKL--DKAPMADFSSAT-ITTGSLPPGDHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTEFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYG-NNWVVTTQDFLGQQPQNDFDKTIAYTSGEG-VL-QW-----KYDAANGTGTLTQGNTTWD----MHGKKG-----------------N----DLNAGK-------NLLFTGN-NG----EVVLQNSVNQGAGYLQFAGD--YRVSALN--GQTWMGGGIITDKGTHVLWQVNGVAGDNLHKTGEGTLTVNGTGVNAGGLKVGDGTVILNQQADADGKVQAFSSVGIASGRPTVVLSDSQQVNP----DNISWGYRGGRLELNGNNLTFTRLQAADYGAIITNNS-EKKSTVTLDLQTLKASDINVPVNTVSI----FG-----------GRGAPGDLYYDSSTKQ--YFILKASS-YSPFFSDLNNSSVWQNVGKDRNKAIDTVKQQKIEASS--QPYMYHGQLNGNMDVNIPQLSG-KDVLALDGSVNLPEGSITKKSGTLIFQGHPVIHAGTT-------------------TSSSQSDWETRQFTLEKLKLDAATFHLSRN-GKMQGDINATNGSTVILGSSRVFTDRSDGTGNAVFSVEGSATATTVGDQSDYSGNVTLENKSSL------ 141 142 ATVSAEIPYQIFRDFAENKGQFTPGTTNISIYDKQGNLVGKL--DKAPMADFSSAT-ITTGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYG-NNWVVTTQDFLGQQPQNDFDKTIAYTSGEG-VL-QW-----KYDAANGTGTLTQGNTTWD----MHGKKG-----------------N----DLNAGK-------NLLFTGN-NG----EVVLQNSVNQGAGYLQFAGD--YRVSALN--GQTWMGGGIITDKGTHVLWQVNGVAGD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 142 143 ATVSAEIPYQIFRDFAENKGQFTPGTTNISIYDKQGNLVGKL--DKAPMADFSSAT-ITTGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYG-NNWVVTTQDFLGQQPQNDFDKTIAYTSGEG-VL-QW-----KYDAANGTGTLTQGNTTWD----MHGKKG-----------------N----DLNAGK-------NLLFTGN-NG----EVVLQNSVNQGAGYLQFAGD--YRVSALN--GQTWMGGGIITDKGTHVLWQVNGVAGDNLHKTGEGTLTVNGTGVN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 143 144 ATVSAEIPYQIFRDFAENKGQFTPGTTNISIYDKQGNLVGKL--DKAPMADFSSAT-ITTGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYG-NNWVVTTQDFLGQQPQNDFDKTIAYTSGEG-VL-QW-----KYDAANGTGTLTQGNTTWD----MHGKKG-----------------N----DLNAGK-------NLLFTGN-NG----EVVLQNSVNQGAGYLQFAGD--YRVSALN--GQTWMGGGIITDKGTHVLWQVNGVAGDNLHKTGEGTLTVNGTGVNAGGLKVGDGTVILNQQADADGKVQAFSSV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 144 145 ------------------------------------------------MADFSSAT-ITTGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKIRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYG-NNWVVTTQGFLGQQPQNDFDKTIAYTSGEG-VL-QW-----K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 145 146 ATVSAEIPYQIFRDFAENKGQFTPGTTNIFIYGKQGHLVGKL--DKAPMTDFSSATIITTGSLPPGNHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTTVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDIGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGQM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSLQKKWVLIGVLSSG-------------TNYE-NNWVVTTQDFLGQQPQNDFDKTIAYTSGEG-VL-QW-----KYDAANGTGTLTQGNTTWD----MHGKKG-----------------N----DLNAGK-------NLLFTGN-NG----EVVLQNSVNQGGGYLQFAGD--YRVSALN--GQTWMGGGIITDKGTHVLWQVNGVAGDNLHKTGEGTLTVNGTGVNIGGLKVGDGTVILNQQADADGKVQAFSSVDIASGRPTVVLSDSQQVNP----DNISWGYRGGRLDLNGNNLTFTRLQAADYGAIITNNS-EKKSTVTLDFQTLKASDINVPVNTV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 146 147 ATVSAEIPYQIFRDFAENKGQFTPESTNISIYDKLGNLVGKL--DKAPMADFSSAT-ITTGSLPPGDHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YAKN-TYTAVGTNN---------------------NS----G--LDIKTRRLSKLVTEVAPAEVSDVGAVSGA---------YQAGGRFTAFYRLGGGMQYVK-----------DKNGNRTQVYT-------------NGGFLVGGT----VSALNSYN--NGHM-ITAQ---TGDIFN----------PANGPLANYLNMGDSGSPLFAYDSWQKKWVLIGVLSSG-------------SDYG-NNWVVTTQDFLGQQPQNDFDKTITYISGGG-AL-QW-----KYDAANGTGTLTQGNTRWD----MHGKKG-----------------N----DLNAGK-------NLLFTGN-NG----EVVLQNSVNQGAGYLQFAGD--YRVSALN--GQTWMGGGIITDKGTHVLWQVNGVAGDNLHKIGEGTLTVNGTGVNAGGLKVGDGSVILSQQADADGKVQAFSSVNIASGRPTVVLSDAQQVNP----DNISWGYRGGRLDLNGNNLTFTRLQAADYGAIITNNS-EKKSTVTLDLQTLKASDINVPINTVNI----FG-----------GKGSPGDLYYDSSTKN--YYILKASS-YSPFFSDMNNSSVWQNVGKDRNKAIDTVKQQKIEASS--QPYMYHGQLNGNMDVNIPQLSG-KDILALDGSVNLPEGSITKKSGTLIFQGHPVIHAGTT-------------------TSASQSDWDTRQFTLGKLKLDAATFHLSRN-GQMQGDINATNGSTVILG---------------------------------------------------- 147 148 ATVSAEIPYQTFRDFAENKGLFTPGATNIAIYDKQGNQVDEL--GKAPMADFSSAT-ITTGSLPPGDHTLY-SPQYVVTAKH---VSG--S--DTMSFG-----------------YARN-TYTAVGTNN---------------------NA----G--LDIKTRRLSKLVTEVAPAEVSDVGALSGA---------YQAGGRFTAFYRLGGGMQYIK-----------DKNGNLTQVYT-------------NGGFLVGGT----VGALNSYH--NGQM-ITAQ---TSDIFN----------PANGPLANYLNMGDSGSPLFAYDSWDEKWVLIGVLSSG-------------SDYG-NNWVVTTQTFLSQQPQNDFDKTITYSAGAG-AL-QW-----KYDAVNGTGSLTQGNTIWD----MHGKKG-----------------N----DLNAGK-------NLLLTGN-NG----EVVLQDSVNQGAGYLQFAND--YKVSALN--GQTWMGGGVITDKGTHVLWQVNGVAGDNLHKLGEGTLMVNGTGVNAGGLKVGDGTVILNQQLDTDGKVQAFSSVDISSGRPTVVLSDSRQVNP----DNISWGYRGGRLDLNGNNLTFTRIQAADYGAIITNTS-EKKSTVTLDLQSLKASDINVPINTINF----LG-----------GRGTPGDLYLVESTGQ--YYILKESS-YSPFFSDLNNPNIWQSVGKDRNKAIDTVKHQKIEASS--QPYMYHGQLNGNMDVNIPQLSG-KDVLTLDGSVNLPEGSITKKSGTLIFQGHPIIHAGTT-------------------TSASQSDWETRQFTLGKLKLDAATFYLSRN-GQMHGDINAVNGSTVILG---------------------------------------------------- 148 149 ATVNADISYQTFRDFAENKGAFIVGSSNINIYDKNGVLVGVL--DKAPMPDFSSAT-MNTGTLPPGDHTLY-SPQYVVTAKH---VNG--S--DIMSFG-----------------HIQN-NYTVVGENK---------------------HN----S--LDIKTRRLNKIVTEVAPAEVSSVGAVNGA---------YQEGGRFTAFYRLGGGLQYIK-----------DKNGNLTPVYT-------------NGGFLTGGT----ISALNSYN--NGQM-ITAP---TGDIFN----------PANGPLANYLNKGDSGSPLFAYDSLEKKWVLVGVLSSG-------------SEHG-NNWVVTTQDFLHQQLKHDFDKTISYDSKKG-SL-QW-----RYDKNAGVGTLSQEGVVWD----MHGKKG-----------------E----DLNAGK-------NLQFTGN-NG----EVILHDSIDQGAGYLQFFDN--YTVTSLT--DQTWTGGGIITEKGVNVLWQVNGVNDDNLHKVGEGTLTVNGKGVNNGGLKVGDGTVILNQRPDDNGHKQAFSSINISSGRATVILSDANQVNP----DKISWGYRGGTLDLNGNNVTFTRLQAADYGAIISNNN-KNKSELTLKLQTLNENDISV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 149 150 ATVNADISYQTFRDFAENKGAFIVGASNINIYDKNGVLVGVL--DKAPMPDFSSAT-MNTGTLPPGDHTLY-SPQYVVTAKH---VNG--S--DIMSFG-----------------HIQN-NYTVVGENN---------------------HN----S--LDIKTRRLNKIVTEVAPAEVSSVGAVNGA---------YQEGGRFTAFYRLGGGLQYIK-----------DKNGNLTPVYT-------------NGGFLTGGT----ISALNSYN--NGQM-ITAP---TGDIFN----------PANGPLANYLNKGDSGSPLFAYDSLEKKWVLVGVLSSG-------------SEHG-NNWVVTTQDFLHQQLKHDFDKTISYDSKKG-SL-QW-----RYDKNAGVGTLSQEGVVWD----MHGKKG-----------------E----DLNAGK-------NLQFTGN-NG----EVILHDSIDQGAGYLQFFDN--YTVTSLT--DQTWTGGGIITEKGVNVLWQVNGVNDDNLHKVGEGTLTVNGKGVNNGGLKVGDGTVILNQRPDDNGHKQAFSSINISSGRATVILSDANQVNP----DKISWGYRGGTLDLNGNNVTFTRLQAADYGAIISNNN-KNKSELTLKLQTLNENDISVDVKTYEV----FG-----------GHGSPGDLYYVSASNT--YFILKSKA-YGPFFSDLDNTNVWQNVGHDRDKAIQIVKQQKIEESS--QPYMFHGQLNGYMDVNIHPLSG-KDVLTLDGSVNLPEGVITKKSGTLIFQGHPVIHAGMT-------------------TSAGQSDWENRQFTMDKLKLDAATFHLSRN-ARMQGDISAANGSTVILG---------------------------------------------------- 150 151 ATVNADISYQTFRDFAENKGAFIVGASNINIYDKNGVLVGVL--DKAPMPDFSSAT-MNTGTLPPGDHTLY-SPQYVVTAKH---VNG--S--DIMSFG-----------------HIQN-NYTVVGENN---------------------HN----S--LDIKTRRLNKIVTEVAPAEVSSVGAVNGA---------YQEGGRFTAFYRLGGGLQYIK-----------DKNGNLTPVYT-------------NGGFLTGGT----ISALNSYN--NGQM-ITAP---TGDIFN----------PANGPLANYLNKGDSGSPLFAYDSLEKKWVLVGVLSSG-------------SEHG-NNWVVTTQDFLHQQLKNDFDKTISYDSKKG-SL-QW-----RYDKNAGVGTLSQEGVVWD----MHGKKG-----------------E----DLNAGK-------NLQFTGN-NG----EVILHDSIDQGAGYLQFFDN--YTVTSLT--DQTWTGGGIITEKGVNVLWQVNGVNDDNLHKVGEGTLTVNGKGVNNGGLKVGDGTVILNQRPDDNGHKQAFSSINISSGRATVILSDANQVNP----DKISWGYRGGTLDLNGNNVT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 151 152 ATVNADISYQTFRDFAENKGAFIVGASNINIYDKNGVLVGVL--DKAPMPDFSSAT-MNTGTLPPGDHTLY-SPQYVVTAKH---VNG--S--DIMSFG-----------------HIQN-NYTVVGENN---------------------HN----S--LDIKTRRLNKIVTEVAPAEVSSVGAVNGA---------YQEGGRFTAFYRLGGGLQYIK-----------DKNGNLTPVYT-------------NGGFLTGGT----ISALSSYN--NGQM-ITAP---TGDIFN----------PANGPLANYLNKGDSGSPLFAYDSLEKKWVLIGVLSSG-------------SEYG-NNWVVTTQDFLNQQPKHDFDKTISYDSKKG-SL-QW-----RYDKDAGVGTLSQEGVVWD----MHGKKG-----------------E----DLNAGK-------NLQFTGN-NG----EVILHDSIDQGAGYLQFFNN--YTVTSLT--DQTWTGGGIITEKGVNVLWQVNGVNNDNLHKVGEGTLTVNGKGVNNGGLKVGDGTVILNQRPDDNGHKQAFSSINISSGRATVILSDANQVNP----DKISWGYRGGTLDLNGNNVTFTRLQAADYGAIISNNN-KNKSELTLKLQTLNENDISV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 152 153 ATVNADISYQTFRDFAENKGAFIVGASNINIYDKNGVLVGVL--DKAPMPDFSSAT-MNTGTLPPGDHTLY-SPQYVVTAKH---VNG--S--DIMSFG-----------------HIQN-NYTVVGENN---------------------HN----S--LDIKIRRLNKIVTEVAPAEISSVGAVNGA---------YQEGGRFKAFYRLGGGLQYIK-----------DKNGNLTPVYT-------------NGGFLTGGT----ISALSSYN--NGQM-ITAP---TGDIFN----------PANGPLANYLNKGDSGSPLFAYDSLDKKWVLVGVLSSG-------------SEHG-NNWVVTTQDFLHQQPKHDFDKTISYDSEKG-SL-QW-----RYNKNSGVGTLSQESVVWD----MHGKKG-----------------G----DLNAGK-------NLQFTGN-NG----EIILHDSIDQGAGYLQFFDN--YTVTSLT--DQTWTGGGIITEKGVNVLWQVNGVNDDNLHKVGEGTLTVNGKGVNNGGLKVGDGTVILNQRPDDNGHKQAFSSINISSGRATVILSDANQVNP----DKISWGYRGGTLDLNGNNVNFTRLQAADYGAIVSNNN-KNKSELTLKLQTLNENDISVDVKTYEV----FG-----------GHGSPGDLYYVPASNT--YFILKSKA-YGPFFSDLDNTNVWQNVGHDRDKAIQIVKQQKIGESS--QPYMFHGQLNGYMDVNIHPLSG-KDVLTLDGSVNLPEGVITKKSGTLIFQGHPVIHAGMT-------------------TSAGQSDWENRQFTMDKLRLDAATFHLSRN-AHMQGDISAANGSTVILGSSRVFTDKNDGTGNAVSSVEGSSIATTAGDQSYYSGNVLLENHSSL------ 153 154 ATVRADIPYQTFRDFAENKGSFFVGNTNIAIKNNAGNIIGYL--DKAPMPDFSSAS-VAATLLVPGEHTLY-SPQYVVTARH---VNGTSFGTTNISFG-----------------YKQN-EYSVIEEHN---------------------HP----SSMADIKTLRLNKLVTEVAPAIVSTSGAVNNA---------YNKNSIYTAFYRLGGGDKNIK-----------NINGTTTHVDG---------------DFLIGGT----IGYLSSYN--NNLM-ISSG---TAQIFNE---------NYQGYLANYLQPGDSGSPLFGYNSKTKEWELIGVTSSM-------------SVNG-NNWAVTSRDFLSQKPKNDFEPVVRHTDTSA-PL-VW-----KY--SSNTGEIKNNQDYYQ----IH-----------------------------SGK-------NLYFTGK-NG----HVDIQSSVNQGAGYLQFTDS--YTVSTTN--GSSWIGGGIIVEDGATVNWGVNGVEGDNLHKVGSGTLVINGIGENKGGLKVGDGLVILAQKKDNDNNIQAASSLDISSGRATVKLTDSNQINP----NNITWGYRGGRLDINGSDIEFSRLNASDYGAIIENGS-SYKSTLTLNLKAINPDDIIVKMNQMDF----RG-----------GNGTPGELYLDK--DTGRYYILKKNTYSPTFFG--INSNEWTFAGNNKTQAIAFYKNIKVASSS--TPYMYHGQLNGYMDVHVPSLSG-SNILALDGSVDI-SGDFEKETGTLIFQGHPVLHAGKR-------------------PSPSQNDWEVRQFNLNVLKLDGAEFHLSRN-STMKGDIHANN-SVVILGSNKVYTDNNDGTGNTIESVAGESTPDNDKDISTLSGYIYSDN---------- 154 155 --IRGDIDLQTYKDFAENKGQFLPGTENIKIYDKSGNLVGTL--DSAPMPDFSAVGRKFAVIG-SGEATLF-HPAYMITANHVVTNGMKNNQKQIVVFG----------------SDASNESYQIVETRA---------------------HA-------SDTNTMRLSKLVTDVAPTPVGNSNGGVGA---------FGKNGIYSAFYRVGSGKKAII-----------NKNGSTQTLSG---------------DFLVGGP----LPSLSDG---GSQW-INAN---INNIFNA---------NKNGPLPTVPQLGDSGSPIYAYNT----------------------------------------------------------------------------------------------------------------------------QKNAGK-------LL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 155 156 --MSDSFDVQTYRDFAENRGIFDVNAKDVAIYDKDGNYVGTI--PK--MMNFDGVADAH-----AGEAALVGGPGFIATVSHDYNNQTITF---TKRFGATQG-----------TPFYD--AYRSVVIKN---------------------AWGNQTNYTYDYRVQRLSKIVTEAEYAPYLTDPE-------------YLDNMKGRLVLRAGSGTQAIA-----------TGNGKQDTVNG-------------AYSYLTGGT----LVFEGQASAPGTGEPDPEN---AKTYPAYRFWYNFKKPTESNPLPTGVLAGDSGSPSYVFNENSGQWEWVGAGQSQ-----------GGSGYG-EFSQMRSGNQWASDYVDSFNRTVSVSEGGGDLL--W-----NVTDAEGNGTFVQGDISTDYIGLASGVRG-----------------DTSTQGTRATDAQIGACSNLVFDGS-GG----TIVLQGSVDTGAGSLTFNRD--YVLSDGGDSSRRLNTAGFVVNKGATVTTLLTGASGDEWRKIGEGDLIVSGHGNNAADINVGGGGLLVLDRDG-----YAARNVKLNGGGVMVRLAGENQVSG-----EFIFGHRGGVVDMYGH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 156 157 -----------YLDLAQNKGVFQPGAYGVKTPLKNGGEF-SF--PEVTIPDFSP---VS---A-KGATTAI-GDAYSVTASH---NGTIHHAVKTQTWG--------------------QSDYHYVDR-V---------------------TK-------GDFAVQRLDKFVVETAGATEHVDFNLSAAEALERYGIDF-NGKKQLIGFRVGAGATGV----------------TSYGVGQ-AY----------NPLLRSASM----FQL-NWNNM------LATN-------------------NT-GGFYNEVTGGDSGSGFYLYDNQRKKWVILG--TTY-----------G-KAFS-SKDTWAFFARYDQNTVDTLKN-------------TF-----TQEVNLNGQKMTVNNKNIT----VNGNTT-----------------AIELTKNN--KNK-----DLKFHGG--G----NIQLTDNLNSGSGGLIFDEGQYYSITGKD---KTYKGAGIDIGKDTVVDWSVKGEANDNLHKTGSGTLNVNVA--QGNNLKMGDGTVVLNAA-------KAFNAIYVASGRGTVKLGQADALDKNSDYRGIYFTSRGGTLDLNGFSQSFKKIAATDVGTIITNTS-DKTATLSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 157 158 QMDTRNFWIRDYLDLAQNKGAFQPGAYGVKTPLKNGGEF-SF--PEVTIPDFSP---VS---A-KGATTAI-GNAYSVTASH---NGTIHHAIKTQTWG--------------------QSDYHYVDR-M---------------------TK-------GDFAVQRLDKFVVETAGATEHVDFGLSAAEALERYGVEF-NGKKQIIGFRVGSGATGV----------------TSYGVGQ-AY----------NPLLRSASM----FQL-NWNNM------YASN-------------------NT-GGFYNEVTGGDSGSGFYLYDNQKKKWVILG--TLT-----------G-KVFS-SKDSWAFFARYDQNTVDTLKN-------------TF-----TQEVNLKGQKMTVNNKNIT----VNGNTT-----------------AIELTKNN--KNK-----DLKFHGG--G----SIELTDNLNSGAGGLIFDEGQHYSITGKD---KTYKGAGIDIGKDTVVDWSVKGEANDNLHKTGAGALNVNVA--QGNNLKMGDGTVVLNAA-------KAFNAIYVASGRGTVKLGQADAMDKNSDYRGIYFTTRGGTLDLNGFSQSFKKIAATDVGTIITNTS-DKTATLSLQNPSSYVYHGNITGNTNIE-------------------------------------------------------------------------H---TGTQKSADSSLIIDGNIDTHNDIFIRNSQLRLQGHATTHAIFRDGPQFCYVPGVLCDKDYVTDFARLESEANKKNNSAYKTNNQVASFDQPDWENRHFRFKTLNLENAEFTTARN-SVVEGDIVASNSTLKLGG-DVPVFIDMYDGINITGNGFGFRQDVREGRSADDGSSSYTGNITLQKGSTLD 158 159 -----------YLDLAQNKGAFQPGAYGVKTPLKNGGEF-SF--PEVTIPDFSP---VS---A-KGATTAI-GNAYSVTASH---NGTIHHAVKTQTWG--------------------QSDYHYVDR-V---------------------TK-------GDFAVQRLDKFVVETAGATEHADFNLSAAEALERYGIEF-NGKKQIIGFRVGSGATGV----------------GPYRVGQ-AY----------NPLLRSASM----FQL-NWNNM------LATN-------------------NT-GGFYNEVTGGDSGSGFYLYDNQRKKWVILG--TTY-----------G-KAFS-SKDTWAFFARYDQNTVDTLKN-------------TF-----TQEVNLNGQKMTANNKNIT----VNGNTT-----------------AIELTRNN--KNK-----DLKFHGG--G----SIELTDNLNSGTGGLIFDEGQHYSVIGKD---KTYKGAGIEIGKGTVVDWSVKGVANDNLHKTGAGTLNVNVA--QGNNLKTGDGTVFLNAE-------KAFNAIYVASGRGTVKLGQADALDKNSDYRGIYFTSRGGTLDLNGFSQSFKKIAATDVGTIITNTS-DKTATLSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 159 160 -----------YLDLAQNKGVFQPGAYGVKTPLKNGGEF-SF--PEVTIPDFSP---VS---A-KGATTAI-GDAYSVTASH---NGTIHHAVKTQTWG--------------------QSDYHYVDR-V---------------------TK-------GDFAVQRLDKFVVETAGATEHADFNLSAAEALERYGIEF-NGKKQIIGFRVGSGATGV----------------GPYRVGQ-AY----------NPLLRSASM----FQL-NWNNM------LATN-------------------NT-GGFYNEVTGGDSGSGFYLYDNQRKKWVILG--TTY-----------G-KAFS-SKDTWAFFARYDQNTVDTLKN-------------TF-----TQEVNLNGQKMTINNKNIT----VNGNTT-----------------AIELTRNN--KNK-----DLKFHGG--G----SIELTDNLNSGTGGLIFDERQHYSVIGKD---KNYKGAGVEIGKGTVVDWSVKGVANDNLHKTGAGTLNVNVA--QGNNLKTGDGTVFLNAE-------KAFNAIYVASGRGTVKLGQADALDKNSDYRGIYFTSRGGTLDLNGFSQSFKKIAATDVGTIITNTS-DKTATLSL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 160 161 ----DNVWARDYLDLAQNKGVFKAGATNVSIQLKNGQTF-NF--PNVPIPDFSP---AS---N-KGATTSI-GGAYSVTATH---NGTTHHAISTQNWG--------------------QSSYKYIDR-M---------------------TN-------GDFAVTRLDKFVVETTGVKNSVDFSLNSHDALERYGVEI-NGEKKIIGFRVGAGTTYTV------------QNGNTYSTGQ-VY----------NPLLLSASM----FQL-NWDNK------RPYN-------------------NT-TPFYNETTGGDSGSGFYLYDNVKKEWVMLG--TLF-----------G-IASS-GADVWSILNQYDENTVNGLKN-------------KF-----TQKVQLNNNTMSL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 161 162 ----DNVWARDYLDLAQNKGVFKAGATNVSIQLKNGQTF-NF--PNVPIPDFSP---AS---N-KGATTSI-GGAYSVTATH---NGTTHHAISTQNWG--------------------QSSYKYIDR-M---------------------TN-------GDFAVTRLDKFVVETTGVKNSVDFSLNSHDALERYGVEI-NGEKKIIGFRVGAGTTYTV------------QNGNTYSTGQ-VY----------NPLLLSASM----FQL-NWDNK------RPYN-------------------NT-TPFYNETTGGDSGSGFYLYDNVKKEWVMLG--TLF-----------G-IASS-GADVWSILNQYDENTVNGLKN-------------KF-----TQKVQLNNNTMSLNSDSFT----LAGNNT-----------------AVE-KNNN--NYK-----DLSFSGG--G----SINFDNDVNIGSGGLIFDAGHHYTVTGNN---KTFKGAGLDIGDNTTVDWNVKGVVGDNLHKIGAGTLNVNVS--QGNNLKTGDGLVVLNSA-------NAFDNIYMASGHGVVKINHSAALNQNNDYRGIFFTENGGTLDLNGYDQSFNKIAATDIGALITN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 162 163 QLNIDNVWARDYLDLAQNKGVFKAGATNVSIQLKNGQTF-NF--PNVPIPDFSP---AS---N-KGATTSI-GGAYSVTATH---NGTTHHAISTQNWG--------------------QSSYKYIDR-M---------------------TN-------GDFAVTRLDKFVVETTGVKNSVDFSLNSHDALERYGVEI-NGEKKIIGFRVGAGTTYTV------------QNGNTYSTGQ-VY----------NPLLLSASM----FQL-NWDNK------RPYN-------------------NT-TPFYNETTGGDSGSGFYLYDNVKKEWVMLG--TLF-----------G-IASS-GADVWSILNQYDENTVNGLKN-------------KF-----TQKVQLNNNTMSLNSDSFT----LAGNNT-----------------AVE-KNNN--NYK-----DLSFSGG--G----SINFDNDVNIGSGGLIFDAGHHYTVTGNN---KTFKGAGLDIGDNTTVDWNVKGVVGDNLHKIGAGTLNVNVS--QGNNLKTGDGLVVLNSA-------NAFDNIYMASGHGVVKINHSAALNQNNDYRGIFFTENGGTLDLNGYDQSFNKIAATDIGALITNSA-VQKAVLSVNNQSNYMYHGSVSGNTEIN-------------------------------------------------------------------------H---QFDTQKNNSRLILDGNVDITNDINIKNSQLTMQGHATSHAVFREGGVTCMLPGVICEKDYVSGIQQQENSANKNNNTDYKTNNQVSSFEQPDWENRLFKFKTLNLINSDFIVGRN-AIVVGDISANNSTLSLSGKDTKVHIDMYDGKNITGDGFGFRQDIKDGVSVSPESSSYFGNVTLNNHSLLD 163 164 -----------YLDLAQNRGEFRPGATNVQLMMKDGKIF-HF--PELPVPDFSA---VS---N-KGATTSI-GGAYSVTATH---NGTQHHAITTQSWD--------------------QTAYKASNR-V---------------------SS-------GDFSVHRLNKFVVETTGVTESADFSLSPEDAMKRYGVNY-NGKEQIIGFRAGAGTTSTI------------LNGKQYLFGQ-NY----------NPDLLSASL----FNL-DWKNKS-----YIYT-------------------NR-TPFKNSPIFGDSGSGSYLYDKEQQKWVFHGVTSTV-----------G-FISS-TNIAWTNYSLFNNILVNNLKK-------------NF-----TNTMQLDGKKQ-------------------------------------ELSSII--KDK-----DLSVSGG--G----VLTLKQDTDLGIGGLIFDKNQTYKVYGKD---KSYKGAGIDIDNNTTVEWNVKGVAGDNLHKIGSGTLDVKIA--QGNNLKIGNGTVILSAE-------KAFNKIYMAGGKGTVKINAKDALSESGNGE-IYFTRNGGTLDLNGYDQSFQKIAATDAGTTVTNSN-VKQSTLSLT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 164 165 -LDINNIWTRDYLDLAQNRGEFRPGATNVQLMMKDGKIF-HF--PELPVPDFSA---VS---N-KGATTSI-GGAYSVTATH---NGTQHHAITTQSWD--------------------QTAYKASNR-V---------------------SS-------GDFSVHRLNKFVVETTGVTESADFSLSPEDAMKRYGVNY-NGKEQIIGFRAGAGTTSTI------------LNGKQYLFGQ-NY----------NPDLLSASL----FNL-DWKNKS-----YIYT-------------------NR-TPFKNSPIFGDSGSGSYLYDKEQQKWVFHGVTSTV-----------G-FISS-TNIAWTNYSLFNNILVNNLKK-------------NF-----TNTMQLDGKKQ-------------------------------------ELSSII--KDK-----DLSVSGG--G----VLTLKQDTDLGIGGLIFDKNQTYKVYGKD---KSYKGAGIDIDNNTTVEWNVKGVAGDNLHKIGSGTLDVKIA--QGNNLKIGNGTVILSAE-------KAFNKIYMAGGKGTVKINAKDALSESGNGE-IYFTRNGGTLDLNGYDQSFQKIAATDAGTTVTNSN-VKQSTLSLTNTDAYMYHGNVSGNISIN-------------------------------------------------------------------------HIINTTQQHNNNANLIFDGSVDIKNDISVRNAQLTLQGHATEHAIFKEGNNNCPIP-FLCQKDYSAAIKDQESTVNKRYNTEYKSNNQIASFSQPDWESRKFNFRKLNLENATLSIGRD-ANVKGHIEAKNSQIVLG--NKTAYIDMFSGRNITGEGFGFRQQLRSGDSAGESSFNGSLSAQNSKITVGD 165 166 -----------FLDLGQNKGQFKAGERNVTVQLKDGSTF-TL--PDLPIPDFSV---AA---K-NAAVTSI-GGAYGISASH---YAGNHYGVATSTWG--------------------QTTYKKIDRIS---------------------SR----T--SDFAAHRFDKFVVETTGVKNSVDFSLSSAEALERYGVMY-YGKKQLAGFRVGNGMMPVV------------QNNTSVSTGG-AY----------VPELVNGGL----IGI-NWGSPT-----NVFT-------------------NK-TAFTAMPQQGDSGSVALLYDNELKEWVALGTLSTL-----------G--FNK-NGYVFTLYGRYDNNSVTQLKD-------------YY-----TQNINTGGQDVKITQDNYT----INDEKT-----------------EFQITDNKTGRK------DLKFTGG--G----NIIFESSLDQGNGGLIFGENEKYNISGEN---TTFRGAGIDIGKDSTVDWNIKYASNDNLHKIGEGVLDVKQT--QNTNLKTGNGTVILSAE-------KAFNNIYMASGNGTVKLNHTNALAG-GDYNGIYFTKNGGTLDLNGYDQTFGKIAATDSGTTITNTNNENSSTLKIT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 166 167 -----------YLDLAQNKGIFQPGATDVTITLKNGDKF-SF--HNLSIPDFSG---AA---A-SGAATAI-GGSYSVTVAH---NKKNPQAAETQVYA--------------------QSSYKVVDRRN---------------------S--------NDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI------------NGESKISTNS-AY----------SHDLLSASL----FEVTQWDSYGM----MIYK-------------------ND-KTFRNLEIFGDSGSGAYLYDNKLEKWVLVG--TTH-----------G-IASV-NGDQLTWITKYNDKLVSELKD-------------TY-----SHKINLNGNNVTIKNTDIT----LHQNNA-----------------DTTGTQEKITKDK-----DIVFTNG--G----NVLFKDNLDFGSGGIIFDEGHEYNINGQG---FTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKK--QGANIKIGEGNVILNEE-------GTFNNIYLASGNGKVILNKDNSLGN-DQYAGIFFTKRGGTLDLNGHNQTFTRIAATDDGTTITNSDTTKEAVLAI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 167 168 -----------YLDLAQNKGIFQPGATDVTITLKNGDKF-SF--HNLSIPDFSG---AA---A-SGAATAI-GGSYSVTVAH---NKKNPQAAETQVYA--------------------QSSYKVVDRRN---------------------S--------NDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI------------NGESKISTNS-AY----------SHDLLSASL----FEVTQWDSYGM----MIYK-------------------ND-KTFRNLEIFGDSGSGAYLYDNKLEKWVLVG--TTH-----------G-IASV-NGDQLTWITKYNDKLVSELKD-------------TY-----SHKINLNGNNVTIKNTDIT----LHQNNA-----------------DTTGTQEKITKDK-----DIVFTNG--G----NVLFKDNLDFGSGGIIFDEGHEYNINGQG---FTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKK--QGANIKIGEGNVILNEE-------GTFNNIYLASGNGKVILNKDNSLGN-DQYAGIFFTKRGGTLDLNGHNQTFTRIAATDDGTTITNSDTTKEAVLAI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 168 169 -----------YLDLAQNKGIFQPGATDVTITLKNGDKF-SF--HNLSIPDFSG---AA---A-SGAATAI-GGSYSVTVAH---NKKNPQAAETQVYA--------------------QSSYKVVDRRN---------------------S--------NDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI------------NGESKISTNS-AY----------SHDLLSASL----FEVTQWDSYGM----MIYK-------------------ND-KTFRNLEIFGDSGSGAYLYDNKLEKWVLVG--TTH-----------G-IASV-NGDQLTWITKYNDKLVSELKD-------------TY-----SHKINLNGNNVTIKNTDIT----LHQNNA-----------------DTTGTQEKITKDK-----DIVFTNG--G----NVLFKDNLDFGSGGIIFDEGHEYNINGQG---FTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKK--QGANIKIGEGNVILNEE-------GTFNNIYLASGNGKVILNKDNSLGN-DQYAGIFFTKRGGTLDLNGHNQTFTRIAATDDGTTITNSDTTKEAVLAI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 169 170 NIDISNVWARDYLDLAQNKGIFQPGATDVTITLKNGDKF-SF--HNLSIPDFSG---AA---A-SGAATAI-GGSYSVTVAH---NKKNPQAAETQVYA--------------------QSSYKVVDRRN---------------------S--------NDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI------------NGESKISTNS-AY----------SHDLLSASL----FEVTQWDSYGM----MIYK-------------------ND-KTFRNLEIFGDSGSGAYLYDNKLEKWVLVG--TTH-----------G-IASV-NGDQLTWITKYNDKLVSELKD-------------TY-----SHKINLNGNNVTIKNTDIT----LHQNNA-----------------DTTGTQEKITKDK-----DIVFTNG--G----NVLFKDNLDFGSGGIIFDEGHEYNINGQG---FTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKK--QGANIKIGEGNVILNEE-------GTFNNIYLASGNGKVILNKDNSLGN-DQYAGIFFTKRGGTLDLNGHNQTFTRIAATDDGTTITNSDTTKEAVLAINNEDSYIYHGNINGNIKLT-------------------------------------------------------------------------H--NINSQDKKTNAKLILDGSVNTKNDVEVSNASLTMQGHATEHAIFRSTANHCSLVFLCGTDWVTVLKETESSYNKKFNSDHKSNNQQTSFDQPDWKTGVFKFDTLHLNNADFSISRN-ANVEGNISANKSAITIG--DKNAYIDNLAGKNITNNGFDFKQTISTNLSIGETKFTGGITAHNSQIAIGD 170 171 --------------------------------------------------DFSG---AA---A-SGAATAI-GGSYSVTVAH---NKKNPQAAETQVYA--------------------QSSYRVVDRRN---------------------S--------NDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI------------NGESKISTNS-AY----------SHDLLSASL----FEVTQWDSYGM----MIYK-------------------ND-KTFRNLEIFGDSGSGAYLYDNKLEKWVLVG--TTH-----------G-IASV-NGDQLTWITKYNDKLVSELKD-------------TY-----SHKINLNGNNVTIKNTDIT----LHQNNA-----------------DTTGTQEKITKDK-----DIVFTNG--G----DVLFKDNLDFGSGGIIFDEGHEYNINGQG---FTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKK--QGANIKIGEGNVILNEE-------GTFNNIYLASGNGKVILNKDNSLGN-DQYAGIFFTKRGGTLDLNGHNQTFTRIAATDDGTTITNSDTTKEAVLAINNEDSYIYHGNINGNIKLT-------------------------------------------------------------------------H--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 171 172 -----------YLDLAQNKGVFQPGATDVTITLKNGDKF-SF--HNLSIPDFSG---AA---A-SGAATAI-GGSYSVTVAH---NKKNPQAAETQVYA--------------------QSSYKVVDRRN---------------------S--------NDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI------------NGESKISTNS-AY----------SHDLLSASL----FEVTQWDSYGM----MIYK-------------------ND-KTFRNLEIFGDSGSGAYLYDNKLEKWVLVG--TTH-----------G-IASV-NGDQLTWITKYNDKLVSELKD-------------TY-----SHKINLNGNNVTIKNTDIT----LHQNNA-----------------DTTGTQENITKDK-----DIVFTNG--G----NVLFKDNLDFGSGGIIFDEGHEYNINGQG---FTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKK--QGANIKIGEGNVILNEE-------GTFNNIYLASGNGKVILNKDNSL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 172 173 -----------YLDLAQNKGIFQPGATDVTITLKNGDKF-SF--HNLSIPDFSG---AA---A-SGAATAI-GGSYSVTVAH---NKKNPQAAETQVYA--------------------QSSYKVVDRRN---------------------S--------NDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI------------NGESKISTNS-AY----------SHDLLSASL----FEVTQWDSYGM----MIYK-------------------ND-KTFRNLEIFGDSGSGAYLYDNKLEKWVLVG--TTH-----------G-IASV-NGDQLTWITKYNDKLVSELKD-------------TY-----SHKINLNGNNVTIKNTDIT----LHQNNA-----------------DTTGTQEKITKDK-----DIVFTNG--G----NVLFKDNLDFGSGGIIFDEGHEYNINGQG---FTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKK--QGANIKIGEGNVILNEE-------GTFNNIYLASGNGKVILNKDNSLGN-DQYAGIFFTKRGGTLDL-GND---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 173 174 -----------YLDLAQNKGIFQPGATDVTITLKNGDKF-SF--HNLSIPDFSG---AA---A-SGAATAI-GGSYSVTVAH---NKKNPQAAETQVYA--------------------QSSYKVVDRRN---------------------S--------NDFEIQRLNKFVVETVGATPAETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI------------NGESKISTNS-AY----------SHDLLSASL----FEVTQWDSYGM----MIYK-------------------ND-KTFRNLEIFGDSGSGAYLYDNKLEKWVLVG--TTH-----------G-IASV-NGDQLTWITKYNDKLVSELKD-------------TY-----SHKINLNGNNVTIKNTDIT----LHQNNA-----------------DTTGTQEKITKDK-----DIVFTNG--G----NVLFKDNLDFGSGGIIFDEGHEYNINGQG---FTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKN--RGQI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 174 175 NMDISKAWARDYLDLAQNKGVFQPGSTHVKIKLKDGTDF-SF--PALPVPDFSS---AT---A-NGAATSI-GGAYAVTVAH---NAKNKSSANYQTYG--------------------STQYTQINRMT---------------------TG-------NDFSIQRLNKYVVETRGADTSFNYNENNQNIIDRYGVDVGNGKKEIIGFRVGSGNTTF----------------SGIKTSQ-TY----------QADLLSASL----FHITNLRANTVGGNKVEYE-------------------ND-SYFTNLTTNGDSGSGVYVFDNKEDKWVLLG--TTH-----------G-IIGN-GKTQKTYVTPFDSKTTNELKQ-------------LF-----IQNVNIDNNTATIGGGKIT----IGNTTQ-----------------DIEKNKNN--QNK-----DLVFSGG--G----KISLKENLDLGYGGFIFDENKKYTVSAEGNNNVTFKGAGIDIGKGSTVDWNIKYASNDALHKIGEGSLNVIQA--QNTNLKTGNGTVILGAQ-------KTFNNIYVAGGPGTVQLNAENALGE-GDYAGIFFTENGGKLDLNGHNQTFKKIAATDSGTTITNSNTTKESVLSVNNQNNYIYHGNVDGNVRLE-------------------------------------------------------------------------H--HLDTKQDNARLILDGDIQANS---ISIKNAPLVMQGHATDHAIFRTTKTNNCPEFLCGVDWVTRIKNAENSVNQKNKTTYKSNNQVSDLSQPDWETRKFRFDNLNIEDSSLSIARN-ADVEGNIQAKNSVINIG--DKTAYIDLYSGKNITGAGFTFRQDIKSGDSIGESKFTGGIMATDGSISIGD 175 176 -----------YMDFAQNKGIFQAGATNIEIVKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKNHHSVATQNWG--------------------NSTYKQTDWNT---------------------SH-------PDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNY-KGEKKLIAFRAGSGVVSVK------------KNGRITPFNEVSY----------KPEMLNGSF----VHIDDWSGWL-----ILTN-------------------NQFDEFNNIASQGDSGSALFVYDNQKKKWVVAG--TVW-----------GIYNYA-NGKNHAAYSKWNQTTIDNLKN-------------KY-----SYNVDMSGAQVATIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----DILLKSSFDNGAGGLVFNDKKTYRVNGDD---FTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGDGTLDV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 176 177 -MDISNFYIRDYMDFAQNKGIFQAGATNIEIVKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKNHHSVATQNWG--------------------NSTYKQTDWNT---------------------SH-------PDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNY-KGEKKLIAFRAGSGVVSVK------------KNGRITPFNEVSY----------KPEMLNGSF----VHIDDWSGWL-----ILTN-------------------NQFDEFNNIASQGDSGSALFVYDNQKKKWVVAG--TVW-----------GIYNYA-NGKNHAAYSKWNQTTIDNLKN-------------KY-----SYNVDMSGAQVATIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----DILLKSSFDNGAGGLVFNDKKTYRVNGDD---FTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGDGTLDVRKT--QNTNLKTGEGLVILGAE-------KTFNNIYITSGDGTVRLNAENALSG-GEYNGIFFAKNGGTLDLNGYNQSFNKIAATDSGAVITNTSTKKSILSLNNTADYIYHGNINGNLDVLQ-------------------------------------------------------------------------H-----HETKKENRRLILDGGVDTTNDISLRNTQLSMQGHATEHAIYRDGAFSCSLPAPMRFLCGSDYVAGMQNTEADAVKQNGNAYKTNNAVSDLSQPDWETGTFRFGTLHLENSDFS-VGRNANVIGDIQASKSNITIGDTTAYIDLHAGKNITGDGFGFRQNIVRGNSQGETLFTGGITAEDSTIVI 177 178 -----------YMDFAQNKGIFQAGATNIEIVKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKNHHSVATQNWG--------------------NSTYKQTDWNT---------------------SH-------PDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNY-KGEKKLIAFRAGSGVVSVK------------KNGRITPFNEVSY----------KPEMLNGSF----VHIDDWSGWL-----ILTN-------------------NQFDEFNNIASQGDSGSALFVYDNQKKKWVVAG--TVW-----------GIYNYA-NGKNHAAYSKWNQTTIDNLKN-------------KY-----SYNVDMSGAQVATIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----DILLKSSFDNGAGGLVFNDKKTYRVNGDD---FTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGDGTLDVRKT--QNTNLKTGEGLVILGAE-------KTFNNIYITSGDGTVRLNAENALSG-GEYNGIFFAKNGGTLDLNGYNQSFNKIAATDSGAVITNTSTKKSNFI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 178 179 -----------YMDFAQNKGIFQAGATNIEIVKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKNHHSVATQNWG--------------------NSTYKQTDWNT---------------------SH-------PDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNY-KGEKKLIAFRAGSGVVSVK------------KNGRITPFNEVSY----------KPEMLNGSF----VHIDDWSGWL-----ILTN-------------------NQFDEFNNIASQGDSGSALFVYDNQKKKWVVAG--TVW-----------GIYNYA-NGKNHAAYSKWNQTTIDNLKN-------------KY-----SYNVDMSGAQVATIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----DILLKSSFDNGAGGLVFNDKKTYRVNGDD---FTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGDGTLDVRKT--QNTNLKTGEGLVILGAE-------KTFNNIYITSGDGTARLNAENALSG-GEYNGIFFAKNGGTLDLNGYNQSFNKIAATDSGAVITNTST-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 179 180 -----------YMDFAQNKGIFQAGATNIEIVKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKNHHSVATQNWG--------------------NSTYKQTDWNT---------------------SH-------PDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNY-KGEKKLIAFRAGSGVVSVK------------KNGRITPFNEVSY----------KPEMLNGSF----VHIDDWSGWL-----ILTN-------------------NQFDEFNNIASQGDSGSALFVYDNQKKKWVVAG--TVW-----------GIYNYA-NGKNHAAYSKWNQTTIDNLKN-------------KF-----SYKVDMSGAQVATIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----DILLKSSFDNGAGG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 180 181 -----------YMDFAQNKGIFQAGATNIEIVKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKNHHSVATQNWG--------------------NSTYKQTDWNT---------------------SH-------PDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNY-KGEKKLIAFRAGSGVVSVK------------KNGRITPFNEVSY----------KPEMLNGSF----VHIDDWSGWL-----ILTN-------------------NQFDEFNNIASQGDSGSALFVYDNQKKKWVVAG--TVW-----------GIYNYA-NGKNHAAYSKWNQTTIDNLKN-------------KF-----SYKVDMSGAQVATIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----DILLKSSFDNGAGGLVFNDKKTYRVNGDD---FTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGDGTLDVRKT--QNTNLKTGEGLVILGAE-------KTFNNIYITSGDGTVRLNAENALSG-GEYNGIFFAKNGGTLDLNGYNQSFNKIAATDSGAVITNTST-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 181 182 -------------DFAQNKGIFQAGATNIEIVKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKNHHSVATQNWG--------------------NSTYKQTDWNT---------------------SH-------PDFAVSRLDKFVVETRGATEGADISLSKQQALERYGVNY-KGEKKLIAFRAGSGVVSVK------------KNGRITPFNEVSY----------KPEMLNGSF----VHIDDWSGWL-----ILTN-------------------NQFDEFNNIASQGDSGSALFVYDNQKKKWVVAG--TVW-----------GIYNYA-NGKNHAAYSKWNQTTIDNLKN-------------KY-----SYNVDMSGAQVATIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----DILLKSSFYNGAGGVFF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 182 183 -----------YMDFAQNKGIFQAGATNIEIEKKDGSSL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKTHHSVAEQNWG--------------------NTTYKQADWHT---------------------SH-------PDFAVSRLDKFVVETRGVTEGADTSLSKQQALERYGINY-KGEKKLIAFRAGSGTIGIK------------KDGKTTPFDEVFY----------KPEMLNGSF----VHIDDWSGWL-----VLTN-------------------NQFDEFNNLATQGDSGSALFVYDNEKKKWVVAG--TAW-----------GVYYYS-NGKTHTAYSKWDQNAVDTIKK-------------TF-----SHNVDMTNQQEVTIENGKL----AGIGTD-----------------TSEIKNK-----------DLIFTGG--G----NILLKSSFDNGAGGLVFNDKKTYQINGND---FTFKGAGIDTRNGSTVEWNIRYDNKDNLHKIGDGTLDVRKS--QNTNLKTGDGLVILGAE-------KTFNNIYMASGDGTVRLNAEKALSD-GEYNGIFFAKNGGTLDLNGHNQSFNKIAATDSGAVITN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 183 184 -----------YLDFAQNKGIFQAGATNIEIIKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKTHHSVAAQNWG--------------------NSTYKQVDWYT---------------------SQ-------PDFAVSRLDKYVVETRGATEGADTSLSTQQALERYGVNY-KGEKKLIAFRAGSGKIGIR------------KDGNLTPLDDISY----------KPEMLNGSF----VHIDNWSGWL-----VLTN-------------------NQFDEFNNLATQGDSGSALFVYDNQKKKWVVVG--TAW-----------GVYNYS-NGKNHTAYSRWDQKAIDNLKK-------------NF-----SYNVDMSGVQQVTIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----NILLKSSFDNGAGGLVFNDKKTYQVNGED---FTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGNGTLDVRKS--QNTNLKIGEGLVILGAE-------KTFNNIYMASGDGTVKLNANNALNG-DDYAGVFFTENGGTLDLNGYDQVFKYIAATDSGTTITNTNKDKPATLSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 184 185 -----------YLDFAQNKGIFQAGATNIEIIKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKTHHSVAAQNWG--------------------NSTYKQVDWYT---------------------SQ-------PDFAVSRLDKYVVETRGATEGADTSLSTQQALERYGVNY-KGEKKLIAFRAGSGKIGIR------------KDGNLTPLDDISY----------KPEMLNGSF----VHIDNWSGWL-----VLTN-------------------NQFDEFNNLATQGDSGSALFVYDNQKKKWVVVG--TAW-----------GVYNYS-NGKNHTAYSRWDQKAIDNLKK-------------NF-----SYNVDMSGVQQVTIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----NILLKSSFDNGAGGLVFNDKKTYQVNGED---FTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGNGTLDVRKS--QNTNLKIGEGLVILGAE-------KTFNNIYMASGDGTVKLNANNALNG-DDYAGVFFTENGGTLDLNGYDQVFKYIAATDSGTTITNTNKDKPATLSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 185 186 -----------YLDFAQNKGIFQAGATNIEIIKKDGSTL-KL--PEVPFPDFSP---VA---N-KGSTTSI-GGAYSITATH---NTKTHHSVAAQNWG--------------------NSTYKQVDWYT---------------------SQ-------PDFAVSRLDKYVVETRGATEGADTSLSTQQALERYGVNY-KGEKKLIAFRAGSGKIGIR------------KDGNLTPLDDISY----------KPEMLNGSF----VHIDNWSGWL-----VLTN-------------------NQFDEFNNLATQGDSGSALFVYDNQKKKWVVVG--TAW-----------GVYNYS-NGKNHTAYSRWDQKAIDNLKK-------------NF-----SYNVDMSGVQQVTIENGKL----TGTGSD-----------------TTDIKNK-----------DLIFTGG--G----NILLKSSFDNGAGGLVFNDKKTYQVNGED---FTFKGAGVDTRNGSTVEWNIRYDNKDNLHKIGNGTLDVRKS--QNTNLKIGEGLVILGAE-------KTFNNIYMASGDGTVKLNANNALNG-DDYAGVFFTENGGTLDLNGYDQVFKYIAATDSGTTITNTNKDKPATLSI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 186 187 -----------YLDFAQNKGKFTAGNENISFIKKDGSVY-KL--PEVPFPDFSP---VA---N-KGATTSI-GGAYSVTATH---NKTSHHAIATQSWG--------------------QTNYKYVDRNT---------------------SN--------DFAVTRLNKYVVETQGIFSGADTSLTKAQALERYGVNF-KGEKKLIAFRAGSGYLALQ------------SNGKSINYKDISY----------IPELLNGSF----VLVENWSSGV-----IQTN-------------------NLFDEFGNRTTAGDSGSPFLLYDNIDKKWVVLG--TLL-----------GEYYYP-NNIVRSAVNVWHQRSVEDLKN-------------KY-----THDVSANGKNI----------------SQ-----------------TSLVNNK-----------DNVIHGG--G----ALNIEGSLNLGNGGLVFDTNQKYSVKGNN---VTYTGAGVDIGENTTVDWYLKGVTNDNLHKIGAGTLDVKVT--QGGNLKTGNGTVVLSAE-------KSFNNIYMASGNGTVKLNADKALGS-GDYAGIFFTENGGTLDLNGHDQAFKYIAATDLGTTITNTNKDKIATLSV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 187 188 ---------QDFFDFAQNKGAFKPGAKNITILKKDGSTL-EL--PDVPFPDFSS---VS---N-KGSTTAI-GGSYTVTATH---NNISHHSISTQGFG--------------------QTNYSYIDR-M---------------------SK-------GDFAVTRVNKFIVEGIGDIESADINLSQSEALEKYGVMY-KGKKQLIGFRAGAGSLIFE------------KNGKLTNNQNVSY----------APDIRNGSF----VLIDGWEGER-----ITTN-------------------NLFDEFKNRTTGGDSGSSLFVYDNEKNKWVILG--TLF-----------GEYHYS-NGQIRSAFNKYDQSLVNKLKD-------------YF-----TQQINLSGKSAVIKNDNIT----INSSSD-----------------SIKVVNQL--KNNKTVQMDLSFNGG--G----TINLEQDLHTGSGGLIFDDSSVYEINGNN---YSYKGAGINTGNSSVVNWNVKGIKGNDLHKIGEGTLNIKAM--QDGNLKIGDGKVVLQAE-------KSFDNIYITSGKATVVIDKNNALNNENEFSGLYFSKNGGVLDLNGYDQFFKKIAATDNGATITNTS-EKTATLSLSSTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 188 189 -MDLTNFYSQDFFDFAQNKGAFKPGAKNITILKKDGSTL-EL--PDVPFPDFSS---VS---N-KGSTTAI-GGSYTVTATH---NNISHHSISTQGFG--------------------QTNYSYIDR-M---------------------SK-------GDFAVTRVNKFIVEGIGDIESADINLSQSEALEKYGVMY-KGKKQLIGFRAGAGSLIFE------------KNGKLTNNQNVSY----------APDIRNGSF----VLIDGWEGER-----ITTN-------------------NLFDEFKNRTTGGDSGSSLFVYDNEKNKWVILG--TLF-----------GEYHYS-NGQIRSAFNKYDQSLVNKLKD-------------YF-----TQQINLSGKSAVIKNDNIT----INSSSD-----------------SIKVVNQL--KNNKTVQMDLSFNGG--G----TINLEQDLHTGSGGLIFDDSSVYEINGNN---YSYKGAGINTGNSSVVNWNVKGIKGNDLHKIGEGTLNIKAM--QDGNLKIGDGKVVLQAE-------KSFDNIYITSGKATVVIDKNNALNNENEFSGLYFSKNGGVLDLNGYDQFFKKIAATDNGATITNTS-EKTATLSLSSTSDYLYHGNISNNIQIR-------------------------------------------------------------------------H-----EHTGKKSDSLLILDGDININNDIHIKNAQVVMQGHATSHTVVKNQACGLPSFLCPVTTTAHLSNLEKNDALKNGVAYKANNQSASFEQPDWEDRQFSFRTMILDNSVFTTSRN-SFLKGDIISSGSDIYFGSKNDVYIDTLAGENITGNGFSFSQNIKKGVSAGDSGFSGGIYSTDGSIRIGDK 189