$VAR1 = undef;

Summary for XT01.001

Summary Substrates

 

Names
MEROPS Name20S constitutive proteasome peptidase complex (eukaryote)
MEROPS Classification
Activity
Catalytic typeThreonine
NC-IUBMBNot yet included in IUBMB recommendations.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/-Scissile bond-/-/-/- (based on 950 cleavages)
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Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 77 54 71 50 65 71 63 70
Pro 66 41 22 11 62 43 48 57
Ala 89 64 78 80 95 63 67 63
Val 79 92 89 92 55 61 66 75
Leu 87 96 84 139 83 129 103 89
Ile 55 53 29 36 19 52 44 53
Met 21 16 20 29 24 14 15 17
Phe 50 39 34 53 32 45 32 35
Tyr 34 25 29 39 33 30 31 20
Trp 22 22 9 29 18 10 18 10
Ser 70 60 71 59 99 54 74 79
Thr 39 46 68 30 52 40 42 55
Cys 5 6 5 4 5 4 6 10
Asn 26 39 43 26 38 34 37 39
Gln 32 31 58 35 35 42 39 28
Asp 22 38 26 62 33 65 53 44
Glu 62 82 69 77 74 77 87 63
Lys 35 62 63 24 59 46 45 57
Arg 39 58 51 48 46 41 47 43
His 24 23 29 27 23 26 21 21