Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with precursor tRNA in 1 mM Ca2+

N4 Full Virion C6 Tail

Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with the precursor tRNA with loop-back 5' leader (sub-conformation 1 of tRNA anticodon arm tilted)

Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with mature tRNA in 5 mM Ca2+

Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with the precursor tRNA with loop-back 5' leader (sub-conformation 2 of tRNA anticodon arm tilted)

N4 Bacteriophage Asymmetric Tail Gating Complex

S. aureus YhaM D193A, 4 N-terminal domains, 2 RNA substrates

S. aureus YhaM D193A hexamer, D3 refinement

S. aureus YhaM D193A hexamer, 2 NTDs, hairpin RNA substrate

Cryo-EM structure of the human beta2-adrenergic receptor in complex with a novel antagonist

S. aureus YhaM D193A hexamer, 3 NTDs, hairpin RNA substrate

Chlorophyll f-containing monomeric far-red Photosystem II from Calothrix sp. NIES-3974

Chlorophyll f-containing dimeric far-red Photosystem II from Chroococcidiopsis thermalis PCC 7203

Composite map of Type II-A CRISPR integrase prespacer catching complex, State II

Subtomogram average of E. scolopes ribosome

Cryo-EM structure of P. urativorans 70S ribosome after 72h acute stress - State 1: Rotated with E-tRNA/P-tRNA

Cryo-EM structure of P. urativorans 70S ribosome after 24h acute stress - State 4: E-tRNA/RaiA/Balon

Cryo-EM (200kV) structure of pyruvate decarboxylase from Neoasaia chiangmaiensis

Cryo-EM structure of P. urativorans 70S ribosome after 72h acute stress - State 2: E-tRNA/P-tRNA/A-tRNA

Cryo-EM structure of P. urativorans 70S ribosome after 24h acute stress - State 3: E-tRNA/P-tRNA/Balon

Cryo-EM structure of human TRPM4 channel in complex with calcium and CBA at 37 degrees Celsius (monomeric TMD-focused map with best-resolved CBA density)

Structural basis of influenza A virus neutralization by broadly active single-domain antibody G2.3 recognizing glycosylated epitope within hemagglutinin stem

Cryo-EM structure of human TRPM4 channel in complex with calcium and NBA at 37 degrees Celsius (monomeric TMD-focused map with best-resolved NBA density)

Cryo-EM structure of the parainfluenza virus hemagglutinin-neuraminidase protein in complex with the human antibodies 5217-2 and PIV3HN-09

Cryo-EM structure of human TRPM4 channel in complex with EGTA and TPPO at 37 degrees Celsius (consensus)

Cryo-EM structure of human TRPM4 channel in complex with calcium and TPPO at 37 degrees Celsius (consensus)

Cryo-EM structure of the parainfluenza virus hemagglutinin-neuraminidase protein in complex with the human antibodies PIV3HN-09 and PIV3HN-13

Cryo-EM structure of human TRPM4 channel in complex with calcium and NBA at 37 degrees Celsius (consensus)

Cryo-EM structure of human TRPM4 channel in complex with calcium and CBA at 37 degrees Celsius (consensus)

Cryo-EM structure of human TRPM4 channel in complex with calcium and CBA and DVT at 37 degrees Celsius (consensus)

Cryo-EM structure of the parainfluenza virus hemagglutinin-neuraminidase protein in complex with the human antibodies PIV3HN-05 and PIV3HN-13

MscS in Glyco-DIBMA Native Nanodiscs (C1 symmetry)

AM12-340 Fab in complex with HIV-1 Env 5MUT-3fill SOSIP

Cryo-EM structure of HCoV-OC43-C2 Spike glycoprotein in complex with 9O-acetyl GD3 sialoglycan

Cryo-EM Structure of the MgtA Tetramer at 2.7 A Resolution

Cryo-EM structure of MgtA with bound AMPPCP and magnesium

Heparin-induced trans tetrameric complex of VEGF, VEGFR2 and Neuropilin 1

Heparin-induced cis tetrameric complex of VEGF, VEGFR2 and Neuropilin 1

Dimeric complex of VEGF, VEGFR2 and Neuropilin 1

Cryo-EM Structure of MgtA in the E2-P State at 2.7 A Resolution

Cryo-EM structure of human TRPM4 channel in complex with EGTA and NC1 at 37 degrees Celsius (consensus)

Consensus map of full-length human VPS13C in complex with calmodulin

Cryo-EM structure of human TRPM4 channel in complex with calcium and TPPO at 18 degrees Celsius (consensus)

Cryo-EM structure of human TRPM4 channel in complex with calcium and NC1 at 37 degrees Celsius (consensus)

Cryo-EM structure of SULTR-like phosphate distribution transporter

Neuraminidase NA isolated from the H1N1 strain A/Victoria/2570/2019 propagated in eggs in complex with zanamivir

Cryo-EM structure of SULTR-like phosphate distribution transporter with phosphate

VPS13A central bridge domain

VPS13A/Nt-CaM

VPS13A/Ct-XKR1

Cryo-EM of arabidopsis non-translatin ribosome structure

Cryo-EM structure of arabidopsis translating ribosome

focused refined map; map for 40S body from human 48S PIC on Kozak mRNA (Kozak_1)

focused refined map; human eIF3 in 48S PIC on Kozak mRNA (Kozak_2)

consensus map; human 48S PIC on Kozak mRNA with eIF1A W70A mutant

Cryo-EM structure of the Arabidopsis thaliana 40S ribosomal subunit (Head)

Cryo-EM structure of the Arabidopsis thaliana 60S ribosomal subunit

focused refined map; 40S head with TC from human 48S PIC on mRNA (non-Kozak)

Cryo-EM structure of the Arabidopsis thaliana 40S ribosomal subunit

focused refined map; 40S head with TC from human 48S PIC on Kozak mRNA (Kozak_2)

human 48S PIC with mRNA (Kozak_2)

human 48S PIC with mRNA (Kozak_1)

focused refined map; 40S body with eIF1A from human 48S PIC with eIF1A W70A mutant on Kozak mRNA

human 48S PIC with Kozak mRNA and eIF1A W70A mutant

focused refined map; 40S body with eIF1A from human 48S PIC on Kozak mRNA (Kozak_2)

consensus map; human 48S PIC on mRNA (non-Kozak)

focused refined map; 40S head with TC from human 48S PIC with eIF1A W70A mutant on Kozak mRNA

focused refined map; 40S body with eIF1A from human 48S PIC on mRNA (non-Kozak)

human 48S PIC with mRNA (non-Kozak)

consensus map; human 48S PIC on Kozak mRNA (Kozak_2)

focused refined map; 40S head with TC from human 48S PIC on Kozak mRNA (Kozak_1)

focused refined map; human eIF3 in 48S PIC on Kozak mRNA (Kozak_1)

consensus map; human 48S PIC on Kozak mRNA (Kozak_1)

Human Cullin-4 in complex with CAND2

Heimdallarchaeales alpha/beta tubulin microtubule with three seams

Heimdallarchaeales alpha/beta tubulin microtubule with a single seam

P2Y13R-Gq complex bound to ADP (consensus)

Calcium coordinated ABPX fibers from Pyrodictium abyssi

P2Y13R-Gq complex bound to ADP (receptor-focused)

P2Y13R-Gq complex bound to ADP (G protein-focused)

P2Y14R-Gi complex bound to UDP (receptor-focused)

P2Y14R-Gi complex bound to UDP (G protein-focused)

P2Y14R-Gi complex bound to UDP (consensus)

Cryo-EM Structure of Human Protease-Activated Receptor 4 in complex with Gq heterotrimers and ScFv16 bound to Tethered Ligand

P2Y14R-Gi complex bound to UDP

P2Y13R-Gq complex bound to ADP

T-ring-PomB complex in Vibrio cholerae

6-Helix Bundle - with a Clasp (6HB-C)-dimer with 2'-Fluoro-modified pyrimidines (FY RNA)

Composite structure of the sheathed flagellar motor in Vibrio cholerae adopting a lower FOMC conformation

Light chain amyloidosis amyloid fibril - IGLV6-57

Composite structure of the sheathed flagellar motor in Vibrio cholerae adopting a higher FOMC conformation

Flagellar outer membrane complex in Vibrio cholerae at disassembled, closed state

Rod-hook protein in Vibrio cholerae at assembled, opened state

H-ring subunit FlgO and FlgP in Vibrio cholerae at assembled, opened state

10-23 DNAzyme in complex with T7 RNA Polymerase

RBM3 domain of FliF protein in MS-ring of flagellar motor in Vibrio cholerae

GRM1-Acc State Conformation 1 (Consensus Map)

HRV14 3C in complex with single chain antibody YDF and cloverleafRNA-conformation2 splitRNA

Cryo-EM structure of AtubAB mini microtubules from Heimdallarchaeia

Cryo-EM structure of AtubAB heterodimer from Heimdallarchaeia

Integrin AlphaIIbBeta3 bound to Fab of the anti-HPA-1a antibody 26.4

cryo-EM structure of human organic solute transporter in complex with DHEAS

cryo-EM structure of human organic solute transporter in complex with TLCA

cryo-EM structure of human organic solute transporter in complex with fidaxomicin

cryo-EM structure of human organic solute transporter in apo state

cryo-EM structure of human organic solute transporter in complex with ethinylestradiol

Cryo-EM structure of AccA3/AccD4/AccD5/AccE5 in complex with Propionyl-CoA

cryo-EM structure of AccA3/AccD4/AccD5/AccE5 complex from Mycobacterium smegmatis

cryo-EM structure of AccA3-AccE5 complex in the presence of Arachidyl-CoA

AtubAB mini microtubule in situ in E. coli by subtomogram averaging

Cryo-EM structure of human FcRL4 bound to IgA-Fc/J

Constituent EM map: local refinement of putative MUC2 binding domain of rEatAp and Fab G12 from best Fab-containing 2D classes

Cryo-EM structure of BAM from P. aeruginosa PAO1 in complex with Pyocin L1

Raw consensus map of rEatAp complexed with Fab G12

Cryo-EM structure of apo BAM from P. aeruginosa PAO1

Constituent EM map: local refinement of putative MUC2 binding domain of rEatAp and Fv domain of Fab G12

Cryo-EM structure of BAM from P. aeruginosa P28 in complex with Pyocin L2

LPHT-ring in Vibrio cholerae at disassembled, closed state

Cryo-EM structure of the VPS13C N-terminal region in complex with Calmodulin

CryoEM structure of H5N1 A/Texas/37/2024 HA bound to Fab H20

LPHT-ring in Vibrio cholerae at disassembled, closed state

Cryo-EM structure of NRAS(Q61K)-BRIL fusion in complex with Fab(BAG2) and Monobody(Mb24)

Cryo-EM structure of the VPS13C C-terminal region

LPHT-ring subunit with C13 MotX in Vibrio cholerae at assembled state

LPHT-ring in Vibrio cholerae at assembled, opened state

Full-length human VPS13C in complex with calmodulin from the CryoEM composite map

A cryo-EM structure of native C3 protein in a compact conformation.

VgrG1 from Pseudomonas aeruginosa (PA0091)

Tobacco Mosaic Virus (TMV)

Human Mortalin (mitochondrial Hsp70) in complex with GrpE1 phosphorylated at Ser-47

Cryo-EM structure of Yadonushi Virus 1

Human Mortalin (mitochondrial Hsp70) in complex with wild-type GrpE1

RecA 12-monomer mini-filament bound to dsDNA with 7-nt homology at 250ms using time-resolved cryo-EM

Cryo-electron microscopy structure of nanofibers formed by reverse azobenzene peptides.

ALFA-tag-FtnA from E.Coli isolated from in vitro translation reaction

Cryo-EM structure of the aspartate:alanine antiporter AspT WT_TM_Local Refinment

Beta-galactosidase from E.Coli

ALFA-tag-FtnA from E.Coli

Cryo-EM structure of the aspartate:alanine antiporter AspT WT Consensus map

Cryo-EM structure of the aspartate:alanine antiporter AspT WT_SD_Local refinement

SpyTag-FtnA from E.Coli

Choline transporter BetT with C-terminal 142-amino acid deletion

Structure of choline transporter BetT with C-terminal deletion(residues 514-677 deleted)

Choline transporter BetT with C-terminal 18-amino acid deletion

Escherichia coli transcription-translation loosely coupled complex complex (TTC-LC^walked) containing mRNA with a 39 nt long spacer, NusG, NusA, and fMet-tRNAs in E-site and P-site - Map 1

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP5

Focused refinement of Macrocystis pyrifera PSI-FCP around PSI

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP6

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP4

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP1

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP2

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP3

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP10

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP9

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP8

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP13

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP7

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP11

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP15

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP17

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP16

Focused refinement of Macrocystis pyrifera PSI-FCP around FCP19

Focused refinement of Macrocystis pyrifera PSI-FCP around FCPB

Focused refinement of Macrocystis pyrifera PSI-FCP around FCPA

Consensus map of Macrocystis pyrifera PSI-FCP supercomplex

Composite map of Macrocystis pyrifera PSI-FCP supercomplex

Cryo-EM structure of avadomide-organized CRL4-DDB1-CRBN-IKZF3(ZF2-ZF3)-UbcH5a-Ub ubiquitylation assembly

Structure of SB290157 bound to human C3aR in complex with Go (Receptor Ligand Focused map)

Cryo-EM structure of two cPRC1 complexes bound to opposite faces of an endogenous 147-bp mono-nucleosome

Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) in C14 symmetry

Cryo-EM structure of pomalidomide-organized CRL4-DDB1-CRBN-IKZF3(ZF2-ZF3)-UbcH5a-Ub ubiquitylation assembly

Cryo-EM structure of cemsidomide-organized CRL4-DDB1-CRBN-IKZF3(ZF2-ZF3)-UbcH5a-Ub ubiquitylation assembly

Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) with SlkB in C14 symmetry

Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) with SlkA in C14 symmetry

Cryo-EM structure of a single cPRC1 complex engaged on one face of an endogenous 147-bp mononucleosome

Cryo-EM structure of mezigdomide-organized CRL4-DDB1-CRBN-IKZF3(ZF2-ZF3)-UbcH5a-Ub ubiquitylation assembly

Cryo-EM structure of the cPRC1-UbcH5c E3-E2 complex bound to the H2BK120ub-modified nucleosome

Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) with SlkA in C1 symmetry

Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) in C1 symmetry

Pseudomonas aeruginosa (PAO1) Outer membrane PilQ (Secretin) with SlkB in C1 symmetry

Cryo-EM structure of oat globulin fibril, Type 1

Constituent EM map: Focused refinement of NCP_1 in the cPRC1-di-nucleosome(loose) complex.

Cryo-EM structure of Borna disease virus RNA-directed RNA polymerase in complex with Suramin

Cryo-EM structure of Borna disease virus RNA polymerase L protein

Cryo-EM structure of the ncPRC1.1-UbcH5c E3-E2 complex bound to the H2BK120ub-modified nucleosome

Cryo-EM structure of the ncPRC1.6 complex bound to the H2AK119ubH2BK120ub-modified nucleosome

Cryo-EM structure of the ncPRC1.1 complex bound to the H2AK119ubH2BK120ub-modified nucleosome

Cryo-EM structure of the cPRC1 complex bound to an endogenous 184-bp mono-nucleosome

Cryo-EM structure of Borna disease virus RNA polymerase complex

Cryo-EM structure of the ncPRC1.4 complex containing two RNF2-BMI1 bound to the H2AK119ubH2BK120ub-modified nucleosome

Constituent EM map: Focused refinement of NCP_1 in the cPRC1-di-nucleosome (tight) complex

Constituent EM map: Focused refinement of NCP_2 in the cPRC1-di-nucleosome (loose) complex

Low-resolution EM map of the cPRC1-di-nucleosome (loose) complex, used as a template for fitting high-resolution cPRC1-bound nucleosome density maps.

Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_1 in the cPRC1-di-nucleosome (tight) complex

Cryo-EM structure of the cPRC1-di-nucleosome (loose) complex

Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_1 in the cPRC1-di-nucleosome(loose) complex

Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_2 in the cPRC1-di-nucleosome (CBX7) complex

Constituent EM map: Focused refinement of NCP_1 in the cPRC1-di-nucleosome (CBX7) complex

Low-resolution EM map of the cPRC1-di-nucleosome (CBX7) complex, used as a template for fitting high-resolution cPRC1-bound nucleosome density maps

Constituent EM map: Focused refinement of NCP_2 in the cPRC1-di-nucleosome (tight) complex

Cryo-EM structure of the cPRC1-di-nucleosome (CBX7) complex

Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_2 in the cPRC1-di-nucleosome (tight) complex

Cryo-EM structure of the cPRC1-di-nucleosome (tight) complex

Constituent EM map: Focused refinement of RNF2&BMI1 bounded NCP_1 in the cPRC1-di-nucleosome (CBX7) complex

Constituent EM map: Focused refinement of NCP_2 in the cPRC1-di-nucleosome (CBX7) complex

Low-resolution EM map of the cPRC1-di-nucleosome (tight) complex, used as a template for fitting high-resolution cPRC1-bound nucleosome density maps

Cryo-EM structure of the ncPRC1.4 complex containing one RNF2-BMI1 and one RYBP bound to the H2AK119ubH2BK120ub-modified nucleosome

Cryo-EM structure of the ncPRC1.4 complex containing one RNF2-BMI1 and one RYBP bound to the H2AK119ub-modified nucleosome

Cryo-EM structure of the ncPRC1.4 complex containing two RYBP bound to the H2AK119ub-modified nucleosome

Cryo-EM structure of the ncPRC1.4 complex containing one RYBP bound to the H2AK119ub-modified nucleosome

Cryo-EM structure of the ncPRC1.4 complex containing one RNF2-BMI1 bound to the H2AK119ub-modified nucleosome

Cryo-EM structure of yeast ribosome solved with EasyGrid

CryoEM structure of guanidinase from Nitrospira inopinata

Cryo-EM structure of P. urativorans 70S ribosome after 2h acute stress - State 3: E-tRNA/P-tRNA/Balon

SARS-CoV-2 Ancestral strain spike S-cred

Cryo-EM structure of P. urativorans 70S ribosome after 24h acute stress - State 1: Rotated with E-tRNA/P-tRNA

C.t. INO80 chromatin remodeler bound to nucleosome

Cyro-EM structure of the ACT-451840-bound PfMDR1

Cryo-EM map of influenza hemagglutinin (A/Hong Kong/1/1968, H3N2) plunged control sample

Cryo-EM map of influenza hemagglutinin (A/Hong Kong/1/1968, H3N2) following ultrasonic excitation during plunging

Cryo-EM structure of human PRMT5:MEP50 in complex with SAH and compounds 16-19F and HJL-1

XBP1u-stalled RPL4 RNC in complex with NAC

Insulin Receptor bound to Ins-AC-S2

Insulin receptor bound to S961

Novel site 1 interaction of the IR/Ins-AC-S2 complex

E.coli 50S ribosomal subunit bound to compound 48a

Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Composite map

Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Focused map B

Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Focused map A

Cryo-EM structure of human Wntless in its apo state

Cryo-EM structure of human Wntless-Wnt5a 2:2 complex - Consensus map

Escherichia coli transcription-translation loosely coupled complex (TTC-LC^walked) containing mRNA with a 39 nt long spacer, NusG, NusA, and fMet-tRNAs in E-site and P-site

Structure of the T6SS effector protein PdpC

Cryo-EM structure of human Wntless in complex with Wnt5a at 1:1 stoichiometry

The complex of HSV-1 proteins UL9 and ICP8 with forked DNA

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structural determination of lipid-bound Factor VIII

Structure of Geobacillus stearothermophilus RNase P holoenzyme in 5 mM Mg2+

Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with precursor tRNA in 5 mM Ca2+

Structure of Geobacillus stearothermophilus RNase P ribozyme in complex with precursor tRNA with non-complementary 5' leader (sub-conformation 2 of tRNA anticodon arm tilted)

Structure of Geobacillus stearothermophilus RNase P ribozyme in complex with precursor tRNA with non-complementary 5' leader (sub-conformation 1 of tRNA anticodon arm tilted)

Consensus map of E. coli clamp loader DnaX-complex loading beta-clamp onto 10-nt gapped DNA in state 1 the DNA recognition state

cryoEM structure of COMMD-like protein S4Y171 octamer

cryoEM structure of COMMD-like protein S4Y171 octamer

Spermine-blocked open-state cryo-EM structure of human TRPV6 channel in cNW30 nanodiscs

N4 Periplasmic Tunnel Fragment

Focus refined map of E. coli clamp loader sub-complex Psi-Chi

Structure of Geobacillus stearothermophilus RNase P holoenzyme in complex with the precursor tRNA with non-complementary 5' leader

N4 Empty Particle Portal