› › Structure analysis

C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE)

X-ray diffraction
2.2Å resolution
PDB entry 1a07 coloured by chain, front view.
PDB entry 1a07 coloured by chain, side view.
PDB entry 1a07 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Proto-oncogene tyrosine-protein kinase Src and peptide
hide full assembly name
Multimeric state: hetero tetramer
Accessible surface area: 10907.52 Å2
Buried surface area: 3052.31 Å2
Dissociation area: 1,250.31 Å2
Dissociation energy (ΔGdiss): -14.32 kcal/mol
Dissociation entropy (TΔSdiss): 21.08 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-146389

Macromolecules

Proto-oncogene tyrosine-protein kinase Src
Chains: A, B
Length: 107 amino acids
Theoretical weight: 12.3 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P12931 (Residues: 144-249; Coverage: 20%)
Gene names: SRC, SRC1
Pfam: SH2 domain
InterPro:
CATH: SH2 domain
SCOP: SH2 domain
Proto-oncogene tyrosine-protein kinase Src in PDB entry 1a07, assembly 1, front view.
Proto-oncogene tyrosine-protein kinase Src in PDB entry 1a07, assembly 1, side view.
Proto-oncogene tyrosine-protein kinase Src in PDB entry 1a07, assembly 1, top view.
Molecule details ›

Search similar proteins

ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE)
Chains: C, D
Length: 4 amino acids
Theoretical weight: 556 Da
Source organism: Homo sapiens
Expression system: Not provided
ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE) in PDB entry 1a07, assembly 1, front view.
ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE) in PDB entry 1a07, assembly 1, side view.
ACE-MALONYL TYR-GLU-(N,N-DIPENTYL AMINE) in PDB entry 1a07, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links