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STRUCTURAL STUDIES OF THE ENGRAILED HOMEODOMAIN

X-ray diffraction
2.1Å resolution
PDB entry 1enh coloured by chain, front view.
PDB entry 1enh coloured by chain, side view.
PDB entry 1enh coloured by chain, top view.
Source organism: Drosophila melanogaster
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Segmentation polarity homeobox protein engrailed
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Multimeric state: monomeric
Accessible surface area: 3889.07 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-136264
Monomeric assembly 1 of PDB entry 1enh coloured by chemically distinct molecules, front view.
Monomeric assembly 1 of PDB entry 1enh coloured by chemically distinct molecules, side view.
Monomeric assembly 1 of PDB entry 1enh coloured by chemically distinct molecules, top view.
    Assembly 1
Confidence : 95%
No. subunits : 1
Symmetry : None
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3DComplex & QSbio predictionx
No. subunits : 1
Symmetry : None
Evidence : This biological assembly agrees with the prediction of both PISA & EPPIC

Macromolecules

Segmentation polarity homeobox protein engrailed
Chain: A
Length: 54 amino acids
Theoretical weight: 6.62 KDa
Source organism: Drosophila melanogaster
Expression system: Not provided
UniProt:
  • Canonical: P02836 (Residues: 456-509; Coverage: 10%)
Gene names: CG9015, en
Pfam: Homeodomain
InterPro:
CATH: Homeodomain-like
SCOP: Homeodomain
Segmentation polarity homeobox protein engrailed in PDB entry 1enh, assembly 1, front view.
Segmentation polarity homeobox protein engrailed in PDB entry 1enh, assembly 1, side view.
Segmentation polarity homeobox protein engrailed in PDB entry 1enh, assembly 1, top view.
PDBe-KB: UniProt Coverage View: P02836  
1545101520253035404550
 
2040RPRTAFSSEQLARLKREFNENRYLTERRRQQLSSELGLNEAQIKIWFQNKRAKI
UniProt
P02836
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Molecule details ›

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