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Nidogen-1 G2/Perlecan IG3 Complex

X-ray diffraction
2Å resolution
PDB entry 1gl4 coloured by chain, front view.
PDB entry 1gl4 coloured by chain, side view.
PDB entry 1gl4 coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Basement membrane-specific heparan sulfate proteoglycan core protein and Nidogen-1
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Multimeric state: hetero dimer
Accessible surface area: 17159.27 Å2
Buried surface area: 2423.07 Å2
Dissociation area: 1,005.12 Å2
Dissociation energy (ΔGdiss): 8.08 kcal/mol
Dissociation entropy (TΔSdiss): 11.5 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-145322

Macromolecules

Nidogen-1
Chain: A
Length: 285 amino acids
Theoretical weight: 31.35 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: P10493 (Residues: 384-665; Coverage: 23%)
Gene names: Ent, Nid1
Pfam: G2F domain
InterPro:
CATH: Green fluorescent protein
SCOP:
Nidogen-1 in PDB entry 1gl4, assembly 1, front view.
Nidogen-1 in PDB entry 1gl4, assembly 1, side view.
Nidogen-1 in PDB entry 1gl4, assembly 1, top view.
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Basement membrane-specific heparan sulfate proteoglycan core protein
Chain: B
Length: 98 amino acids
Theoretical weight: 10.56 KDa
Source organism: Mus musculus
Expression system: Homo sapiens
UniProt:
  • Canonical: Q05793 (Residues: 1765-1858; Coverage: 3%)
Gene name: Hspg2
Pfam: Immunoglobulin domain
InterPro:
CATH: Immunoglobulins
SCOP: I set domains
Basement membrane-specific heparan sulfate proteoglycan core protein in PDB entry 1gl4, assembly 1, front view.
Basement membrane-specific heparan sulfate proteoglycan core protein in PDB entry 1gl4, assembly 1, side view.
Basement membrane-specific heparan sulfate proteoglycan core protein in PDB entry 1gl4, assembly 1, top view.
Molecule details ›

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