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CRYSTAL STRUCTURE OF THE MEXR REPRESSOR OF THE MEXAB-OPRM MULTIDRUG EFFLUX OPERON OF PSEUDOMONAS AERUGINOSA

Source organism: Pseudomonas aeruginosa
Biochemical function: identical protein binding
Biological process: negative regulation of protein secretion
Cellular component: protein-DNA complex

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF01047
Domain description: MarR family
Occurring in:
  1. Multidrug resistance operon repressor
The deposited structure of PDB entry 1lnw contains 8 copies of Pfam domain PF01047 (MarR family) in Multidrug resistance operon repressor. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000835
Domain description: MarR-type HTH domain
Occurring in:
  1. Multidrug resistance operon repressor
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. Multidrug resistance operon repressor
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. Multidrug resistance operon repressor

Structure domain

CATH CATH domain
1.10.10.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Arc Repressor Mutant, subunit A
Homology: Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Occurring in:
  1. Multidrug resistance operon repressor
The deposited structure of PDB entry 1lnw contains 8 copies of CATH domain 1.10.10.10 (Arc Repressor Mutant, subunit A) in Multidrug resistance operon repressor. Showing 1 copy in chain A.
SCOP SCOP annotation
63379
Class: All alpha proteins
Fold: DNA/RNA-binding 3-helical bundle
Superfamily: "Winged helix" DNA-binding domain
Occurring in:
  1. Multidrug resistance operon repressor
The deposited structure of PDB entry 1lnw contains 8 copies of SCOP domain 63379 (MarR-like transcriptional regulators) in Multidrug resistance operon repressor. Showing 1 copy in chain A.

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