Assemblies
Assembly Name:
Heat-labile enterotoxin
Multimeric state:
hetero heptamer
Accessible surface area:
27568.24 Å2
Buried surface area:
23258.37 Å2
Dissociation area:
2,260.97
Å2
Dissociation energy (ΔGdiss):
-3.7
kcal/mol
Dissociation entropy (TΔSdiss):
12.9
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-139157
Macromolecules
Chains: D, E, F, G, H
Length: 103 amino acids
Theoretical weight: 11.81 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Pfam: Heat-labile enterotoxin beta chain
InterPro:
CATH: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
SCOP: Bacterial AB5 toxins, B-subunits
Length: 103 amino acids
Theoretical weight: 11.81 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P32890 (Residues: 22-124; Coverage: 100%)
Pfam: Heat-labile enterotoxin beta chain
InterPro:
CATH: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
SCOP: Bacterial AB5 toxins, B-subunits
Chain: A
Length: 185 amino acids
Theoretical weight: 21.35 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Pfam: Heat-labile enterotoxin alpha chain
InterPro: Heat-labile enterotoxin, A chain
CATH: Heat-Labile Enterotoxin, subunit A
SCOP: ADP-ribosylating toxins
Length: 185 amino acids
Theoretical weight: 21.35 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P06717 (Residues: 22-206; Coverage: 77%)
Pfam: Heat-labile enterotoxin alpha chain
InterPro: Heat-labile enterotoxin, A chain
CATH: Heat-Labile Enterotoxin, subunit A
SCOP: ADP-ribosylating toxins
Chain: C
Length: 41 amino acids
Theoretical weight: 4.95 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
InterPro: Heat-labile enterotoxin, A chain
CATH: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
SCOP: ADP-ribosylating toxins
Length: 41 amino acids
Theoretical weight: 4.95 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P06717 (Residues: 214-254; Coverage: 17%)
InterPro: Heat-labile enterotoxin, A chain
CATH: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
SCOP: ADP-ribosylating toxins