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CRYSTAL STRUCTURE OF A SMAD MH1 DOMAIN BOUND TO DNA

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: regulation of DNA-templated transcription
Cellular component: transcription regulator complex

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF03165
Domain description: MH1 domain
Occurring in:
  1. Mothers against decapentaplegic homolog 3
The deposited structure of PDB entry 1mhd contains 2 copies of Pfam domain PF03165 (MH1 domain) in Mothers against decapentaplegic homolog 3. Showing 1 copy in chain C [auth A].

InterPro InterPro annotations
IPR003619
Domain description: MAD homology 1, Dwarfin-type
Occurring in:
  1. Mothers against decapentaplegic homolog 3
IPR036578
Domain description: SMAD MH1 domain superfamily
Occurring in:
  1. Mothers against decapentaplegic homolog 3
IPR013019
Domain description: MAD homology, MH1
Occurring in:
  1. Mothers against decapentaplegic homolog 3
IPR013790
Domain description: Dwarfin
Occurring in:
  1. Mothers against decapentaplegic homolog 3

Structure domain

CATH CATH domain
3.90.520.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Smad3; Chain A
Homology: SMAD MH1 domain
Occurring in:
  1. Mothers against decapentaplegic homolog 3
The deposited structure of PDB entry 1mhd contains 2 copies of CATH domain 3.90.520.10 (Smad3; Chain A) in Mothers against decapentaplegic homolog 3. Showing 1 copy in chain C [auth A].
SCOP SCOP annotation
56367
Class: Alpha and beta proteins (a+b)
Fold: SMAD MH1 domain
Superfamily: SMAD MH1 domain
Occurring in:
  1. Mothers against decapentaplegic homolog 3
The deposited structure of PDB entry 1mhd contains 2 copies of SCOP domain 56367 (SMAD MH1 domain) in Mothers against decapentaplegic homolog 3. Showing 1 copy in chain C [auth A].

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