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Crystal Structure of Plasmodium falciparum antioxidant protein (1-Cys peroxiredoxin)

X-ray diffraction
1.8Å resolution
PDB entry 1xiy coloured by chain, front view.
PDB entry 1xiy coloured by chain, side view.
PDB entry 1xiy coloured by chain, top view.
Source organism: Plasmodium falciparum
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Redoxin domain-containing protein
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Multimeric state: monomeric
Accessible surface area: 8473.77 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-177624
Assembly 2
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Assembly Name: Redoxin domain-containing protein
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Multimeric state: monomeric
Accessible surface area: 8770.48 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-177624

Macromolecules

Redoxin domain-containing protein
Chains: A, B
Length: 182 amino acids
Theoretical weight: 21.36 KDa
Source organism: Plasmodium falciparum
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5MYR6 (Residues: 59-240; Coverage: 83%)
Gene names: PF3D7_0729200, prx
Pfam: Redoxin
InterPro:
CATH: Glutaredoxin
SCOP: Glutathione peroxidase-like
Redoxin domain-containing protein in PDB entry 1xiy, assembly 1, front view.
Redoxin domain-containing protein in PDB entry 1xiy, assembly 1, side view.
Redoxin domain-containing protein in PDB entry 1xiy, assembly 1, top view.
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