Assemblies
Assembly Name:
DNA topoisomerase 2-alpha
Multimeric state:
homo dimer
Accessible surface area:
30590.1 Å2
Buried surface area:
6523.81 Å2
Dissociation area:
2,301.45
Å2
Dissociation energy (ΔGdiss):
14.86
kcal/mol
Dissociation entropy (TΔSdiss):
14.53
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-145812
Macromolecules
Chains: A, B
Length: 400 amino acids
Theoretical weight: 45.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam:
InterPro:
Length: 400 amino acids
Theoretical weight: 45.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P11388 (Residues: 29-428; Coverage: 26%)
Pfam:
InterPro:
- Histidine kinase/HSP90-like ATPase superfamily
- Histidine kinase/HSP90-like ATPase domain
- DNA topoisomerase, type IIA
- Ribosomal protein uS5 domain 2-type superfamily
- DNA topoisomerase, type IIA, subunit B, domain 2
- Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
