Assemblies
Multimeric state:
hetero trimer
Accessible surface area:
19254.07 Å2
Buried surface area:
4706.5 Å2
Dissociation area:
1,221.11
Å2
Dissociation energy (ΔGdiss):
11.74
kcal/mol
Dissociation entropy (TΔSdiss):
12.05
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-137735
Macromolecules
Chain: A
Length: 275 amino acids
Theoretical weight: 31.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt: Gene names: HLA-A, HLAA
Pfam:
InterPro:
SCOP:
Length: 275 amino acids
Theoretical weight: 31.86 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt: Gene names: HLA-A, HLAA
Pfam:
InterPro:
- MHC class I-like antigen recognition-like
- MHC class I-like antigen recognition-like superfamily
- MHC classes I/II-like antigen recognition protein
- MHC class I alpha chain, alpha1 alpha2 domains
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
SCOP:
Chain: B
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Immunoglobulin C1-set domain
InterPro:
SCOP: C1 set domains (antibody constant domain-like)
Length: 99 amino acids
Theoretical weight: 11.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Pfam: Immunoglobulin C1-set domain
InterPro:
- Immunoglobulin-like fold
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like domain
- Immunoglobulin C1-set
- Immunoglobulin/major histocompatibility complex, conserved site
- Beta-2-Microglobulin
SCOP: C1 set domains (antibody constant domain-like)