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Crystal structure of T4 Lysozyme V131C synthetic dimer

X-ray diffraction
2Å resolution
PDB entry 2huk coloured by chain, front view.
PDB entry 2huk coloured by chain, side view.
PDB entry 2huk coloured by chain, top view.
Source organism: Escherichia virus T4
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Endolysin
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Multimeric state: homo dimer
Accessible surface area: 17277.29 Å2
Buried surface area: 1733.34 Å2
Dissociation area: 189.44 Å2
Dissociation energy (ΔGdiss): -8.98 kcal/mol
Dissociation entropy (TΔSdiss): 11.98 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-133029

Macromolecules

Endolysin
Chain: A
Length: 164 amino acids
Theoretical weight: 18.63 KDa
Source organism: Escherichia virus T4
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00720 (Residues: 1-164; Coverage: 100%)
Gene name: E
Pfam: Phage lysozyme
InterPro:
CATH: Lysozyme
Endolysin in PDB entry 2huk, assembly 1, front view.
Endolysin in PDB entry 2huk, assembly 1, side view.
Endolysin in PDB entry 2huk, assembly 1, top view.
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