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Crystal structure of E53QbsSHMT with glycine

X-ray diffraction
1.86Å resolution
PDB entry 2vgt coloured by chain, front view.
PDB entry 2vgt coloured by chain, side view.
PDB entry 2vgt coloured by chain, top view.
Source organism: Geobacillus stearothermophilus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Serine hydroxymethyltransferase
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Multimeric state: homo dimer
Accessible surface area: 27192.14 Å2
Buried surface area: 9374.98 Å2
Dissociation area: 3,807.77 Å2
Dissociation energy (ΔGdiss): 50.75 kcal/mol
Dissociation entropy (TΔSdiss): 14.92 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-181944

Macromolecules

Serine hydroxymethyltransferase
Chain: A
Length: 407 amino acids
Theoretical weight: 44.39 KDa
Source organism: Geobacillus stearothermophilus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q7SIB6 (Residues: 1-405; Coverage: 97%)
Gene name: glyA
Pfam: Serine hydroxymethyltransferase
InterPro:
CATH:
Serine hydroxymethyltransferase in PDB entry 2vgt, assembly 1, front view.
Serine hydroxymethyltransferase in PDB entry 2vgt, assembly 1, side view.
Serine hydroxymethyltransferase in PDB entry 2vgt, assembly 1, top view.
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