› › Structure analysis

ESTROGENIC 17-BETA HYDROXYSTEROID DEHYDROGENASE COMPLEXED DEHYDROEPIANDROSTERONE

X-ray diffraction
2.3Å resolution
PDB entry 3dhe coloured by chain, front view.
PDB entry 3dhe coloured by chain, side view.
PDB entry 3dhe coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: 17-beta-hydroxysteroid dehydrogenase type 1
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 22228.42 Å2
Buried surface area: 6731.8 Å2
Dissociation area: 2,693.55 Å2
Dissociation energy (ΔGdiss): 45.21 kcal/mol
Dissociation entropy (TΔSdiss): 13.92 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-146840

Macromolecules

17-beta-hydroxysteroid dehydrogenase type 1
Chain: A
Length: 327 amino acids
Theoretical weight: 34.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P14061 (Residues: 2-328; Coverage: 100%)
Gene names: E17KSR, EDH17B1, EDH17B2, EDHB17, HSD17B1, SDR28C1
Pfam: short chain dehydrogenase
InterPro:
CATH: NAD(P)-binding Rossmann-like Domain
SCOP: Tyrosine-dependent oxidoreductases
17-beta-hydroxysteroid dehydrogenase type 1 in PDB entry 3dhe, assembly 1, front view.
17-beta-hydroxysteroid dehydrogenase type 1 in PDB entry 3dhe, assembly 1, side view.
17-beta-hydroxysteroid dehydrogenase type 1 in PDB entry 3dhe, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links