Assemblies
Assembly Name:
DNA-directed RNA polymerase
Multimeric state:
hetero tridecamer
Accessible surface area:
137238.52 Å2
Buried surface area:
64518.16 Å2
Dissociation area:
1,203.23
Å2
Dissociation energy (ΔGdiss):
-6.29
kcal/mol
Dissociation entropy (TΔSdiss):
11.21
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-157657
Assembly Name:
DNA-directed RNA polymerase
Multimeric state:
hetero tridecamer
Accessible surface area:
137878.61 Å2
Buried surface area:
63898.95 Å2
Dissociation area:
983.42
Å2
Dissociation energy (ΔGdiss):
-4.66
kcal/mol
Dissociation entropy (TΔSdiss):
11.15
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-157657
Macromolecules
Chains: A, I
Length: 880 amino acids
Theoretical weight: 99.82 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam:
Length: 880 amino acids
Theoretical weight: 99.82 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q980R2 (Residues: 1-880; Coverage: 100%)
Pfam:
- RNA polymerase Rpb1, domain 1
- RNA polymerase Rpb1, domain 2
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
- RNA polymerase Rpb1, clamp domain superfamily
- RNA polymerase Rpb1, domain 1
- DNA-directed RNA polymerase subunit Rpo1N
- DNA-directed RNA polymerase, subunit beta-prime
- RNA polymerase, N-terminal
- RNA polymerase, alpha subunit
- RNA polymerase Rpb1, domain 3
- RNA polymerase Rpb1, funnel domain superfamily
- RNA polymerase Rpb1, domain 4
- RNA polymerase Rpb1, domain 5
Chains: C, M
Length: 395 amino acids
Theoretical weight: 43.87 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam: RNA polymerase Rpb1, domain 5
InterPro:
Length: 395 amino acids
Theoretical weight: 43.87 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: P58192 (Residues: 1-392; Coverage: 100%)
Pfam: RNA polymerase Rpb1, domain 5
InterPro:
- DNA-directed RNA polymerase, subunit beta-prime
- RNA polymerase Rpb1, domain 5
- DNA-directed RNA polymerase subunit Rpo1C
Chains: B, J
Length: 1124 amino acids
Theoretical weight: 126.72 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam:
Length: 1124 amino acids
Theoretical weight: 126.72 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q980R1 (Residues: 1-1124; Coverage: 100%)
Pfam:
- RNA polymerase beta subunit
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 3
- RNA polymerase Rpb2, domain 4
- RNA polymerase Rpb2, domain 5
- RNA polymerase Rpb2, domain 6
- RNA polymerase Rpb2, domain 7
- DNA-directed RNA polymerase, subunit 2
- RNA polymerase, beta subunit, protrusion
- RNA polymerase Rpb2, domain 2
- RNA polymerase Rpb2, domain 2 superfamily
- RNA polymerase Rpb2, domain 3
- RNA polymerase Rpb2, domain 4
- DNA-directed RNA polymerase subunit Rpo2
- RNA polymerase Rpb2, domain 5
- DNA-directed RNA polymerase, subunit 2, hybrid-binding domain
- DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily
- RNA polymerase Rpb2, OB-fold
- RNA polymerase, beta subunit, conserved site
- RNA polymerase Rpb2, domain 7
Chains: D, O
Length: 265 amino acids
Theoretical weight: 30.33 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam:
InterPro:
Length: 265 amino acids
Theoretical weight: 30.33 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: P95989 (Residues: 1-265; Coverage: 100%)
Pfam:
InterPro:
- DNA-directed RNA polymerase subunit Rpo3/Rpb3/RPAC1
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase, RpoA/D/Rpb3-type
- DNA-directed RNA polymerase, 30-40kDa subunit, conserved site
- DNA-directed RNA polymerase, insert domain superfamily
- DNA-directed RNA polymerase, insert domain
Chains: E, Q
Length: 180 amino acids
Theoretical weight: 20.35 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam:
InterPro:
Length: 180 amino acids
Theoretical weight: 20.35 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q980A3 (Residues: 1-180; Coverage: 100%)
Pfam:
InterPro:
- DNA-directed RNA polymerase, subunit E/RPC8
- RNA polymerase Rpb7-like, N-terminal domain superfamily
- RNA polymerase subunit Rpb7-like
- DNA-directed RNA polymerase subunit Rpo7
- RNA polymerase Rpb7-like , N-terminal
- Nucleic acid-binding, OB-fold
- S1 domain
Chains: F, R
Length: 113 amino acids
Theoretical weight: 12.83 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam: RNA polymerase Rpb4
InterPro:
Length: 113 amino acids
Theoretical weight: 12.83 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q7LXK4 (Residues: 1-113; Coverage: 100%)
Pfam: RNA polymerase Rpb4
InterPro:
- DNA-directed RNA polymerase subunit Rpo4
- HRDC-like superfamily
- RNA polymerase subunit Rpb4/RPC9
- HRDC domain superfamily
Chains: G, S
Length: 132 amino acids
Theoretical weight: 14.99 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam: DNA-directed RNA polymerase, subunit G
InterPro:
CATH: Nucleic acid-binding proteins
Length: 132 amino acids
Theoretical weight: 14.99 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q980L5 (Residues: 1-132; Coverage: 100%)
Pfam: DNA-directed RNA polymerase, subunit G
InterPro:
CATH: Nucleic acid-binding proteins
Chains: H, T
Length: 84 amino acids
Theoretical weight: 9.69 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam: RNA polymerase Rpb5, C-terminal domain
InterPro:
Length: 84 amino acids
Theoretical weight: 9.69 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q980Q9 (Residues: 1-84; Coverage: 100%)
Pfam: RNA polymerase Rpb5, C-terminal domain
InterPro:
- RPB5-like RNA polymerase subunit superfamily
- DNA-directed RNA polymerase subunit Rpo5/Rpb5
- RNA polymerase, subunit H/Rpb5 C-terminal
- RNA polymerase, subunit H/Rpb5, conserved site
Chains: K, U
Length: 95 amino acids
Theoretical weight: 10.87 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam: RNA polymerase Rpb6
InterPro:
Length: 95 amino acids
Theoretical weight: 10.87 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q97ZJ9 (Residues: 1-95; Coverage: 100%)
Pfam: RNA polymerase Rpb6
InterPro:
- RPB6/omega subunit-like superfamily
- RNA polymerase, subunit omega/Rpo6/RPB6
- Archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit
- DNA-directed RNA polymerase, 14-18kDa subunit, conserved site
Chains: L, V
Length: 92 amino acids
Theoretical weight: 10.3 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam: RNA polymerase Rpb3/Rpb11 dimerisation domain
InterPro:
Length: 92 amino acids
Theoretical weight: 10.3 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q980K0 (Residues: 1-92; Coverage: 100%)
Pfam: RNA polymerase Rpb3/Rpb11 dimerisation domain
InterPro:
- RNA polymerase, RBP11-like subunit
- DNA-directed RNA polymerase subunit Rpo11-like
- DNA-directed RNA polymerase, RBP11-like dimerisation domain
- DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site
Chains: N, W
Length: 66 amino acids
Theoretical weight: 7.6 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam: RNA polymerases N / 8 kDa subunit
InterPro:
Length: 66 amino acids
Theoretical weight: 7.6 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q980Z8 (Residues: 1-66; Coverage: 100%)
Pfam: RNA polymerases N / 8 kDa subunit
InterPro:
- DNA-directed RNA polymerase subunit RPABC5/Rpb10
- RNA polymerase subunit RPB10
- RNA polymerases, subunit N, zinc binding site
Chains: P, X
Length: 48 amino acids
Theoretical weight: 5.61 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
InterPro:
Length: 48 amino acids
Theoretical weight: 5.61 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q97ZX7 (Residues: 1-48; Coverage: 100%)
InterPro:
- RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4
- RNA polymerase subunit RPABC4/transcription elongation factor Spt4
- DNA-directed RNA polymerase subunit Rpo12
Chains: Y, Z
Length: 104 amino acids
Theoretical weight: 12.2 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
Pfam: RNA polymerase Rpo13 subunit HTH domain
InterPro: RNA polymerase Rpo13 subunit HTH domain
CATH: DNA Excision Repair, Uvrb; Chain A
Length: 104 amino acids
Theoretical weight: 12.2 KDa
Source organism: Saccharolobus solfataricus P2
UniProt:
- Canonical: Q980B8 (Residues: 1-104; Coverage: 100%)
Pfam: RNA polymerase Rpo13 subunit HTH domain
InterPro: RNA polymerase Rpo13 subunit HTH domain
CATH: DNA Excision Repair, Uvrb; Chain A